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Safety and efficacy of low intensity transcranial ultrasound stimulation for depression: A single-blind randomized controlled clinical study.

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Title: Safety and efficacy of low intensity transcranial ultrasound stimulation for depression: A single-blind randomized controlled clinical study.
Authors: Cai X; Department of Neurology, Shenzhen Samii Medical Center, 1 Jinniu West Road, Shenzhen, Guangdong, 518118, China., Sun W; Department of Neurology, Shenzhen Samii Medical Center, 1 Jinniu West Road, Shenzhen, Guangdong, 518118, China., Zheng X; Department of Neurology, Shenzhen Samii Medical Center, 1 Jinniu West Road, Shenzhen, Guangdong, 518118, China., Ding N; Department of Neuroelectrophysiology, Shenzhen Samii Medical Center, 1 Jinniu West Road, Shenzhen, Guangdong, 518118, China., Luo M; Department of Neuroelectrophysiology, Shenzhen Samii Medical Center, 1 Jinniu West Road, Shenzhen, Guangdong, 518118, China., Tu Y; Department of Neurology, Shenzhen Samii Medical Center, 1 Jinniu West Road, Shenzhen, Guangdong, 518118, China., Meng; GreenValley BrainTech (Shenzhen) Medical Technology Co., Ltd., 1008 Songbai Road, Shenzhen, Guangdong, 518000, China., Liu Y; Research centers for Medical AI, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, 1068 Xueyuan Blvd., Shenzhen, Guangdong, 518055, China., Ding S; GreenValley BrainTech (Shenzhen) Medical Technology Co., Ltd., 1008 Songbai Road, Shenzhen, Guangdong, 518000, China., Yuan B; Department of Neurology, Shenzhen Samii Medical Center, 1 Jinniu West Road, Shenzhen, Guangdong, 518118, China. Electronic address: 13825258808@163.com., Long X; Research centers for Medical AI, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, 1068 Xueyuan Blvd., Shenzhen, Guangdong, 518055, China; State Key Laboratory of Biomedical Imaging Science and System, 1068 Xueyuan Blvd., Shenzhen, Guangdong, 518055, China; Guangdong Provincial Key Laboratory of Multimodality Non-Invasive Brain-Computer Interfaces, 1068 Xueyuan Blvd., Shenzhen, Guangdong, 518055, China. Electronic address: xj.long@siat.ac.cn.
Source: Journal of affective disorders [J Affect Disord] 2026 Feb 01; Vol. 394 (Pt B), pp. 120666. Date of Electronic Publication: 2025 Nov 11.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7906073 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-2517 (Electronic) Linking ISSN: 01650327 NLM ISO Abbreviation: J Affect Disord Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
PubTypeId: academicJournal
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  Data: Safety and efficacy of low intensity transcranial ultrasound stimulation for depression: A single-blind randomized controlled clinical study.
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  Data: <searchLink fieldCode="AU" term="%22Cai+X%22">Cai X</searchLink>; Department of Neurology, Shenzhen Samii Medical Center, 1 Jinniu West Road, Shenzhen, Guangdong, 518118, China.<br /><searchLink fieldCode="AU" term="%22Sun+W%22">Sun W</searchLink>; Department of Neurology, Shenzhen Samii Medical Center, 1 Jinniu West Road, Shenzhen, Guangdong, 518118, China.<br /><searchLink fieldCode="AU" term="%22Zheng+X%22">Zheng X</searchLink>; Department of Neurology, Shenzhen Samii Medical Center, 1 Jinniu West Road, Shenzhen, Guangdong, 518118, China.<br /><searchLink fieldCode="AU" term="%22Ding+N%22">Ding N</searchLink>; Department of Neuroelectrophysiology, Shenzhen Samii Medical Center, 1 Jinniu West Road, Shenzhen, Guangdong, 518118, China.<br /><searchLink fieldCode="AU" term="%22Luo+M%22">Luo M</searchLink>; Department of Neuroelectrophysiology, Shenzhen Samii Medical Center, 1 Jinniu West Road, Shenzhen, Guangdong, 518118, China.<br /><searchLink fieldCode="AU" term="%22Tu+Y%22">Tu Y</searchLink>; Department of Neurology, Shenzhen Samii Medical Center, 1 Jinniu West Road, Shenzhen, Guangdong, 518118, China.<br /><searchLink fieldCode="AU" term="%22Meng%22">Meng</searchLink>; GreenValley BrainTech (Shenzhen) Medical Technology Co., Ltd., 1008 Songbai Road, Shenzhen, Guangdong, 518000, China.<br /><searchLink fieldCode="AU" term="%22Liu+Y%22">Liu Y</searchLink>; Research centers for Medical AI, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, 1068 Xueyuan Blvd., Shenzhen, Guangdong, 518055, China.<br /><searchLink fieldCode="AU" term="%22Ding+S%22">Ding S</searchLink>; GreenValley BrainTech (Shenzhen) Medical Technology Co., Ltd., 1008 Songbai Road, Shenzhen, Guangdong, 518000, China.<br /><searchLink fieldCode="AU" term="%22Yuan+B%22">Yuan B</searchLink>; Department of Neurology, Shenzhen Samii Medical Center, 1 Jinniu West Road, Shenzhen, Guangdong, 518118, China. Electronic address: 13825258808@163.com.<br /><searchLink fieldCode="AU" term="%22Long+X%22">Long X</searchLink>; Research centers for Medical AI, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, 1068 Xueyuan Blvd., Shenzhen, Guangdong, 518055, China; State Key Laboratory of Biomedical Imaging Science and System, 1068 Xueyuan Blvd., Shenzhen, Guangdong, 518055, China; Guangdong Provincial Key Laboratory of Multimodality Non-Invasive Brain-Computer Interfaces, 1068 Xueyuan Blvd., Shenzhen, Guangdong, 518055, China. Electronic address: xj.long@siat.ac.cn.
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  Data: <searchLink fieldCode="JN" term="%227906073%22">Journal of affective disorders</searchLink> [J Affect Disord] 2026 Feb 01; Vol. 394 (Pt B), pp. 120666. <i>Date of Electronic Publication: </i>2025 Nov 11.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%2FNorth-Holland+Biomedical+Press%22">Elsevier/North-Holland Biomedical Press </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>7906073 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1573-2517 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201650327%22">01650327 </searchLink><i>NLM ISO Abbreviation: </i>J Affect Disord <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.jad.2025.120666
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      – Code: eng
        Text: English
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        StartPage: 120666
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      – TitleFull: Safety and efficacy of low intensity transcranial ultrasound stimulation for depression: A single-blind randomized controlled clinical study.
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            – D: 01
              M: 02
              Text: 2026 Feb 01
              Type: published
              Y: 2026
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              Value: 394
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            – TitleFull: Journal of affective disorders
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