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Multi-omics analysis of a pig-to-human decedent kidney xenotransplant.

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Title: Multi-omics analysis of a pig-to-human decedent kidney xenotransplant.
Authors: Schmauch E; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA., Piening BD; Earle A. Chiles Research Institute, Providence Cancer Institute, Portland, OR, USA.; Providence Institute for Clinical Innovation, Providence Health, Portland, OR, USA., Dowdell AK; Earle A. Chiles Research Institute, Providence Cancer Institute, Portland, OR, USA.; Providence Institute for Clinical Innovation, Providence Health, Portland, OR, USA., Mohebnasab M; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Williams SH; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Stukalov A; Seer, Redwood City, CA, USA., Robinson FL; Earle A. Chiles Research Institute, Providence Cancer Institute, Portland, OR, USA., Bombardi R; Illumina, San Diego, CA, USA., Jaffe I; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Khalil K; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Kim J; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Aljabban I; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Eitan T; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., O'Brien DP; Nuffield Department of Medicine, University of Oxford, Oxford, UK., Rophina M; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Wang C; Department of Population Health, NYU Grossman School of Medicine, New York, NY, USA., Bartlett AQ; Earle A. Chiles Research Institute, Providence Cancer Institute, Portland, OR, USA., Zanoni F; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA.; Unit of Nephrology, Dialysis, and Kidney Transplantation, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Albay J; Department of Medicine, NYU Grossman School of Medicine, New York, NY, USA., Andrijevic D; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Maden B; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Mauduit V; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Vikman S; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Argibay D; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Zayas Z; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Wu L; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Moi K; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Lau B; Department of Medicine, Division of Oncology, Stanford University, Stanford, CA, USA., Zhang W; Institute for Systems Genetics, NYU Langone Health, New York, NY, USA., Gragert L; Department of Pathology and Laboratory Medicine, Tulane University, New Orleans, LA, USA., Weldon E; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Gao H; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Hamilton L; Earle A. Chiles Research Institute, Providence Cancer Institute, Portland, OR, USA., Kagermazova L; Institute for Systems Genetics, NYU Langone Health, New York, NY, USA., Camellato BR; Institute for Systems Genetics, NYU Langone Health, New York, NY, USA., Gandla D; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Bhatt R; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Gao S; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Al-Ali RA; Department of Internal Medicine, King Fahd Hospital of the University, Alkhobar, Saudi Arabia., Habara AH; Department of Clinical Biochemistry, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia., Chang A; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Ferdosi S; Seer, Redwood City, CA, USA., Chen HM; Department of Medicine, NYU Grossman School of Medicine, New York, NY, USA., Motter JD; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Thomas SC; Department of Molecular Pathobiology, New York University College of Dentistry, New York, NY, USA., Saxena D; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA.; Department of Molecular Pathobiology, New York University College of Dentistry, New York, NY, USA., Fairchild RL; Department of Immunology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA., Loupy A; Paris Transplant Group, INSERM, Paris, France., Heguy A; Genome Technology center, NYU Langone Health, New York, NY, USA., Crawford A; Illumina, San Diego, CA, USA., Batzoglou S; Seer, Redwood City, CA, USA., Snyder MP; Department of Medicine, Division of Oncology, Stanford University, Stanford, CA, USA., Siddiqui A; Seer, Redwood City, CA, USA., Holmes MV; Medical Research Council, Integrative Epidemiology Unit, University of Bristol, Bristol, UK., Chong AS; Department of Surgery, The University of Chicago, Chicago, IL, USA., Kaikkonen MU; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland., Linna-Kuosmanen S; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Ayares D; Revivicor, Blacksburg, VA, USA., Lorber M; United Therapeutics, Silver Spring, MD, USA., Nellore A; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA., Skolnik EY; Department of Medicine, NYU Grossman School of Medicine, New York, NY, USA., Mattoo A; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA., Tatapudi VS; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Taft R; Illumina, San Diego, CA, USA., Mangiola M; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Guo Q; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Herati RS; Department of Medicine, NYU Grossman School of Medicine, New York, NY, USA., Stern J; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Griesemer A; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Kellis M; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; MIT Computer Science and Artificial Intelligence Laboratory, Cambridge, MA, USA., Boeke JD; Institute for Systems Genetics, NYU Langone Health, New York, NY, USA., Montgomery RA; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Keating BJ; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA. brendan.keating@nyulangone.org.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA. brendan.keating@nyulangone.org.; Institute for Systems Genetics, NYU Langone Health, New York, NY, USA. brendan.keating@nyulangone.org.
Source: Nature [Nature] 2026 Feb; Vol. 650 (8100), pp. 205-217. Date of Electronic Publication: 2025 Nov 13.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
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  Data: Multi-omics analysis of a pig-to-human decedent kidney xenotransplant.
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  Data: <searchLink fieldCode="AU" term="%22Schmauch+E%22">Schmauch E</searchLink>; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Piening+BD%22">Piening BD</searchLink>; Earle A. Chiles Research Institute, Providence Cancer Institute, Portland, OR, USA.; Providence Institute for Clinical Innovation, Providence Health, Portland, OR, USA.<br /><searchLink fieldCode="AU" term="%22Dowdell+AK%22">Dowdell AK</searchLink>; Earle A. Chiles Research Institute, Providence Cancer Institute, Portland, OR, USA.; Providence Institute for Clinical Innovation, Providence Health, Portland, OR, USA.<br /><searchLink fieldCode="AU" term="%22Mohebnasab+M%22">Mohebnasab M</searchLink>; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Williams+SH%22">Williams SH</searchLink>; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Stukalov+A%22">Stukalov A</searchLink>; Seer, Redwood City, CA, USA.<br /><searchLink fieldCode="AU" term="%22Robinson+FL%22">Robinson FL</searchLink>; Earle A. Chiles Research Institute, Providence Cancer Institute, Portland, OR, USA.<br /><searchLink fieldCode="AU" term="%22Bombardi+R%22">Bombardi R</searchLink>; Illumina, San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Jaffe+I%22">Jaffe I</searchLink>; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Khalil+K%22">Khalil K</searchLink>; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Kim+J%22">Kim J</searchLink>; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Aljabban+I%22">Aljabban I</searchLink>; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Eitan+T%22">Eitan T</searchLink>; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22O'Brien+DP%22">O'Brien DP</searchLink>; Nuffield Department of Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Rophina+M%22">Rophina M</searchLink>; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Wang+C%22">Wang C</searchLink>; Department of Population Health, NYU Grossman School of Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Bartlett+AQ%22">Bartlett AQ</searchLink>; Earle A. 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Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland.<br /><searchLink fieldCode="AU" term="%22Linna-Kuosmanen+S%22">Linna-Kuosmanen S</searchLink>; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Ayares+D%22">Ayares D</searchLink>; Revivicor, Blacksburg, VA, USA.<br /><searchLink fieldCode="AU" term="%22Lorber+M%22">Lorber M</searchLink>; United Therapeutics, Silver Spring, MD, USA.<br /><searchLink fieldCode="AU" term="%22Nellore+A%22">Nellore A</searchLink>; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Skolnik+EY%22">Skolnik EY</searchLink>; Department of Medicine, NYU Grossman School of Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Mattoo+A%22">Mattoo A</searchLink>; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Tatapudi+VS%22">Tatapudi VS</searchLink>; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Taft+R%22">Taft R</searchLink>; Illumina, San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Mangiola+M%22">Mangiola M</searchLink>; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Guo+Q%22">Guo Q</searchLink>; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Herati+RS%22">Herati RS</searchLink>; Department of Medicine, NYU Grossman School of Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Stern+J%22">Stern J</searchLink>; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Griesemer+A%22">Griesemer A</searchLink>; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Kellis+M%22">Kellis M</searchLink>; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; MIT Computer Science and Artificial Intelligence Laboratory, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Boeke+JD%22">Boeke JD</searchLink>; Institute for Systems Genetics, NYU Langone Health, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Montgomery+RA%22">Montgomery RA</searchLink>; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Keating+BJ%22">Keating BJ</searchLink>; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA. brendan.keating@nyulangone.org.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA. brendan.keating@nyulangone.org.; Institute for Systems Genetics, NYU Langone Health, New York, NY, USA. brendan.keating@nyulangone.org.
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  Data: <searchLink fieldCode="JN" term="%220410462%22">Nature</searchLink> [Nature] 2026 Feb; Vol. 650 (8100), pp. 205-217. <i>Date of Electronic Publication: </i>2025 Nov 13.
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      – TitleFull: Multi-omics analysis of a pig-to-human decedent kidney xenotransplant.
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            – D: 01
              M: 02
              Text: 2026 Feb
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1476-4687
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              Value: 650
            – Type: issue
              Value: 8100
          Titles:
            – TitleFull: Nature
              Type: main
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