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Mitochondrial dysfunction drives age-related degeneration of the thoracic aorta.

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Title: Mitochondrial dysfunction drives age-related degeneration of the thoracic aorta.
Authors: Dhanekula AS; Division of Cardiothoracic Surgery, University of Washington, Seattle, WA, USA. adhaneku@uw.edu., Harrison BR; Department of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA, USA., Pharaoh G; Department of Radiology, University of Washington, Seattle, WA, USA.; Currently at Gordian Biotechnologies, San Francisco, CA, USA., Mattson-Hughes A; Department of Radiology, University of Washington, Seattle, WA, USA., Tarantini S; Vascular Cognitive Impairment, Neurodegeneration and Healthy Brain Aging Program, Department of Neurosurgery, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA., Stuppard R; Department of Radiology, University of Washington, Seattle, WA, USA., DeRoo SC; Division of Cardiothoracic Surgery, University of Washington, Seattle, WA, USA., Burke CR; Division of Cardiothoracic Surgery, University of Washington, Seattle, WA, USA., Hwang B; Division of Cardiothoracic Surgery, University of Washington, Seattle, WA, USA., Pal JD; Division of Cardiothoracic Surgery, University of Washington, Seattle, WA, USA., Mulligan MS; Division of Cardiothoracic Surgery, University of Washington, Seattle, WA, USA., Marcinek DJ; Department of Radiology, University of Washington, Seattle, WA, USA.; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA.; Institute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA, USA.
Source: GeroScience [Geroscience] 2025 Nov 13. Date of Electronic Publication: 2025 Nov 13.
Publication Type: Journal Article
Journal Info: Publisher: Springer International Publishing Country of Publication: Switzerland NLM ID: 101686284 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2509-2723 (Electronic) Linking ISSN: 25092723 NLM ISO Abbreviation: Geroscience Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Mitochondrial dysfunction drives age-related degeneration of the thoracic aorta.
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  Data: <searchLink fieldCode="AU" term="%22Dhanekula+AS%22">Dhanekula AS</searchLink>; Division of Cardiothoracic Surgery, University of Washington, Seattle, WA, USA. adhaneku@uw.edu.<br /><searchLink fieldCode="AU" term="%22Harrison+BR%22">Harrison BR</searchLink>; Department of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Pharaoh+G%22">Pharaoh G</searchLink>; Department of Radiology, University of Washington, Seattle, WA, USA.; Currently at Gordian Biotechnologies, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Mattson-Hughes+A%22">Mattson-Hughes A</searchLink>; Department of Radiology, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Tarantini+S%22">Tarantini S</searchLink>; Vascular Cognitive Impairment, Neurodegeneration and Healthy Brain Aging Program, Department of Neurosurgery, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.<br /><searchLink fieldCode="AU" term="%22Stuppard+R%22">Stuppard R</searchLink>; Department of Radiology, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22DeRoo+SC%22">DeRoo SC</searchLink>; Division of Cardiothoracic Surgery, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Burke+CR%22">Burke CR</searchLink>; Division of Cardiothoracic Surgery, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Hwang+B%22">Hwang B</searchLink>; Division of Cardiothoracic Surgery, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Pal+JD%22">Pal JD</searchLink>; Division of Cardiothoracic Surgery, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Mulligan+MS%22">Mulligan MS</searchLink>; Division of Cardiothoracic Surgery, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Marcinek+DJ%22">Marcinek DJ</searchLink>; Department of Radiology, University of Washington, Seattle, WA, USA.; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA.; Institute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA, USA.
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  Data: <searchLink fieldCode="JN" term="%22101686284%22">GeroScience</searchLink> [Geroscience] 2025 Nov 13. <i>Date of Electronic Publication: </i>2025 Nov 13.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+International+Publishing%22">Springer International Publishing </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101686284 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2509-2723 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2225092723%22">25092723 </searchLink><i>NLM ISO Abbreviation: </i>Geroscience <i>Subsets: </i>MEDLINE
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              Text: 2025 Nov 13
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