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Identification of a novel MIPEP splice variant with altered substrate-binding properties.

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Title: Identification of a novel MIPEP splice variant with altered substrate-binding properties.
Authors: Otani Y; Laboratory of Molecular Pathology and Metabolic Disease, Faculty of Pharmaceutical Sciences, Tokyo University of Science, 6-3-1 Niijuku, Katsushika-ku, Tokyo, 125-8585, Japan., Kawarai M; Laboratory of Molecular Pathology and Metabolic Disease, Faculty of Pharmaceutical Sciences, Tokyo University of Science, 6-3-1 Niijuku, Katsushika-ku, Tokyo, 125-8585, Japan., Kobayashi M; Department of Nutrition and Food Science, Graduate School of Humanities and Sciences, Ochanomizu University, 2-1-1 Otsuka, Bunkyo-ku, Tokyo, 112-8610, Japan.; Institute for Human Life Science, Ochanomizu University, Japan., Nozaki Y; Laboratory of Molecular Pathology and Metabolic Disease, Faculty of Pharmaceutical Sciences, Tokyo University of Science, 6-3-1 Niijuku, Katsushika-ku, Tokyo, 125-8585, Japan., Uchida R; Laboratory of Molecular Pathology and Metabolic Disease, Faculty of Pharmaceutical Sciences, Tokyo University of Science, 6-3-1 Niijuku, Katsushika-ku, Tokyo, 125-8585, Japan., Tezuka K; Laboratory of Molecular Pathology and Metabolic Disease, Faculty of Pharmaceutical Sciences, Tokyo University of Science, 6-3-1 Niijuku, Katsushika-ku, Tokyo, 125-8585, Japan., Yokoyama M; Laboratory of Molecular Pathology and Metabolic Disease, Faculty of Pharmaceutical Sciences, Tokyo University of Science, 6-3-1 Niijuku, Katsushika-ku, Tokyo, 125-8585, Japan., Mizunoe Y; Laboratory of Molecular Pathology and Metabolic Disease, Faculty of Pharmaceutical Sciences, Tokyo University of Science, 6-3-1 Niijuku, Katsushika-ku, Tokyo, 125-8585, Japan., Narita T; Clinical Research Support Center Mie University Hospital, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan., Haeno H; Research Institute for Biomedical Sciences (RIBS), Tokyo University of Science, 2641 Yamazaki, Noda, Chiba, 278-8510, Japan., Miyano K; Laboratory of Pharmacotherapeutics, Faculty of Pharmacy, Juntendo University, Urayasu, Chiba, 279-0013, Japan., Uezono Y; Department of Pain Control Research, The Jikei University School of Medicine, Tokyo, 105-8461, Japan.; Supportive and Palliative Care Research Support Office, National Cancer Center Hospital East, Chiba, 277-8577, Japan., Higami Y; Laboratory of Molecular Pathology and Metabolic Disease, Faculty of Pharmaceutical Sciences, Tokyo University of Science, 6-3-1 Niijuku, Katsushika-ku, Tokyo, 125-8585, Japan.; Research Institute for Biomedical Sciences (RIBS), Tokyo University of Science, 2641 Yamazaki, Noda, Chiba, 278-8510, Japan.
Source: Biochemistry and biophysics reports [Biochem Biophys Rep] 2025 Oct 29; Vol. 44, pp. 102329. Date of Electronic Publication: 2025 Oct 29 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101660999 Publication Model: eCollection Cited Medium: Internet ISSN: 2405-5808 (Electronic) Linking ISSN: 24055808 NLM ISO Abbreviation: Biochem Biophys Rep Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Identification of a novel MIPEP splice variant with altered substrate-binding properties.
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  Data: <searchLink fieldCode="AU" term="%22Otani+Y%22">Otani Y</searchLink>; Laboratory of Molecular Pathology and Metabolic Disease, Faculty of Pharmaceutical Sciences, Tokyo University of Science, 6-3-1 Niijuku, Katsushika-ku, Tokyo, 125-8585, Japan.<br /><searchLink fieldCode="AU" term="%22Kawarai+M%22">Kawarai M</searchLink>; Laboratory of Molecular Pathology and Metabolic Disease, Faculty of Pharmaceutical Sciences, Tokyo University of Science, 6-3-1 Niijuku, Katsushika-ku, Tokyo, 125-8585, Japan.<br /><searchLink fieldCode="AU" term="%22Kobayashi+M%22">Kobayashi M</searchLink>; Department of Nutrition and Food Science, Graduate School of Humanities and Sciences, Ochanomizu University, 2-1-1 Otsuka, Bunkyo-ku, Tokyo, 112-8610, Japan.; Institute for Human Life Science, Ochanomizu University, Japan.<br /><searchLink fieldCode="AU" term="%22Nozaki+Y%22">Nozaki Y</searchLink>; Laboratory of Molecular Pathology and Metabolic Disease, Faculty of Pharmaceutical Sciences, Tokyo University of Science, 6-3-1 Niijuku, Katsushika-ku, Tokyo, 125-8585, Japan.<br /><searchLink fieldCode="AU" term="%22Uchida+R%22">Uchida R</searchLink>; Laboratory of Molecular Pathology and Metabolic Disease, Faculty of Pharmaceutical Sciences, Tokyo University of Science, 6-3-1 Niijuku, Katsushika-ku, Tokyo, 125-8585, Japan.<br /><searchLink fieldCode="AU" term="%22Tezuka+K%22">Tezuka K</searchLink>; Laboratory of Molecular Pathology and Metabolic Disease, Faculty of Pharmaceutical Sciences, Tokyo University of Science, 6-3-1 Niijuku, Katsushika-ku, Tokyo, 125-8585, Japan.<br /><searchLink fieldCode="AU" term="%22Yokoyama+M%22">Yokoyama M</searchLink>; Laboratory of Molecular Pathology and Metabolic Disease, Faculty of Pharmaceutical Sciences, Tokyo University of Science, 6-3-1 Niijuku, Katsushika-ku, Tokyo, 125-8585, Japan.<br /><searchLink fieldCode="AU" term="%22Mizunoe+Y%22">Mizunoe Y</searchLink>; Laboratory of Molecular Pathology and Metabolic Disease, Faculty of Pharmaceutical Sciences, Tokyo University of Science, 6-3-1 Niijuku, Katsushika-ku, Tokyo, 125-8585, Japan.<br /><searchLink fieldCode="AU" term="%22Narita+T%22">Narita T</searchLink>; Clinical Research Support Center Mie University Hospital, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan.<br /><searchLink fieldCode="AU" term="%22Haeno+H%22">Haeno H</searchLink>; Research Institute for Biomedical Sciences (RIBS), Tokyo University of Science, 2641 Yamazaki, Noda, Chiba, 278-8510, Japan.<br /><searchLink fieldCode="AU" term="%22Miyano+K%22">Miyano K</searchLink>; Laboratory of Pharmacotherapeutics, Faculty of Pharmacy, Juntendo University, Urayasu, Chiba, 279-0013, Japan.<br /><searchLink fieldCode="AU" term="%22Uezono+Y%22">Uezono Y</searchLink>; Department of Pain Control Research, The Jikei University School of Medicine, Tokyo, 105-8461, Japan.; Supportive and Palliative Care Research Support Office, National Cancer Center Hospital East, Chiba, 277-8577, Japan.<br /><searchLink fieldCode="AU" term="%22Higami+Y%22">Higami Y</searchLink>; Laboratory of Molecular Pathology and Metabolic Disease, Faculty of Pharmaceutical Sciences, Tokyo University of Science, 6-3-1 Niijuku, Katsushika-ku, Tokyo, 125-8585, Japan.; Research Institute for Biomedical Sciences (RIBS), Tokyo University of Science, 2641 Yamazaki, Noda, Chiba, 278-8510, Japan.
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  Data: <searchLink fieldCode="JN" term="%22101660999%22">Biochemistry and biophysics reports</searchLink> [Biochem Biophys Rep] 2025 Oct 29; Vol. 44, pp. 102329. <i>Date of Electronic Publication: </i>2025 Oct 29 (<i>Print Publication: </i>2025).
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