Genetic regulation of the metabolome differs by sex, Alzheimer's disease stage, and plasma biomarker status.

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Title: Genetic regulation of the metabolome differs by sex, Alzheimer's disease stage, and plasma biomarker status.
Authors: Eissman JM; The Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, New York, USA.; Gertrude H. Sergievsky Center, Columbia University, New York, New York, USA., Qiao M; The Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, New York, USA.; Gertrude H. Sergievsky Center, Columbia University, New York, New York, USA., Kalia V; Mailman School of Public Health, Columbia University, New York, New York, USA., Zerlin-Esteves M; Gertrude H. Sergievsky Center, Columbia University, New York, New York, USA., Reyes-Dumeyer D; The Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, New York, USA.; Gertrude H. Sergievsky Center, Columbia University, New York, New York, USA., Piriz A; The Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, New York, USA.; Gertrude H. Sergievsky Center, Columbia University, New York, New York, USA., Dubey S; Mailman School of Public Health, Columbia University, New York, New York, USA., Nandakumar R; Mailman School of Public Health, Columbia University, New York, New York, USA., Lee AJ; The Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, New York, USA.; Gertrude H. Sergievsky Center, Columbia University, New York, New York, USA., Lantigua RA; Vagelos College of Physicians and Surgeons, Columbia University, New York, New York, USA., Medrano M; Pontificia Universidad Católica Madre y Maestra, Santiago, República Dominicana., Mejia DR; CEDIMAT, Plaza de la Salud, Dr. Juan Manuel Taveras Rodríguez C/Pepillo Salcedo esq. Arturo Logroño, Santo Domingo, República Dominicana.; Universidad Nacional Pedro Henriquez Ureña, Santo Domingo, República Dominicana., Honig LS; The Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, New York, USA.; Gertrude H. Sergievsky Center, Columbia University, New York, New York, USA.; Vagelos College of Physicians and Surgeons, Columbia University, New York, New York, USA., Dalgard CL; Department of Anatomy, Physiology and Genetics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.; The American Genome Center, Center for Military Precision Health, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA., Miller GW; Mailman School of Public Health, Columbia University, New York, New York, USA., Mayeux R; The Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, New York, USA.; Gertrude H. Sergievsky Center, Columbia University, New York, New York, USA.; Vagelos College of Physicians and Surgeons, Columbia University, New York, New York, USA., Vardarajan BN; The Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, New York, USA.; Gertrude H. Sergievsky Center, Columbia University, New York, New York, USA.; Vagelos College of Physicians and Surgeons, Columbia University, New York, New York, USA.
Source: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2025 Nov; Vol. 21 (11), pp. e70898.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE
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  Data: Genetic regulation of the metabolome differs by sex, Alzheimer's disease stage, and plasma biomarker status.
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  Data: <searchLink fieldCode="AU" term="%22Eissman+JM%22">Eissman JM</searchLink>; The Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, New York, USA.; Gertrude H. Sergievsky Center, Columbia University, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Qiao+M%22">Qiao M</searchLink>; The Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, New York, USA.; Gertrude H. Sergievsky Center, Columbia University, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Kalia+V%22">Kalia V</searchLink>; Mailman School of Public Health, Columbia University, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Zerlin-Esteves+M%22">Zerlin-Esteves M</searchLink>; Gertrude H. Sergievsky Center, Columbia University, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Reyes-Dumeyer+D%22">Reyes-Dumeyer D</searchLink>; The Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, New York, USA.; Gertrude H. Sergievsky Center, Columbia University, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Piriz+A%22">Piriz A</searchLink>; The Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, New York, USA.; Gertrude H. Sergievsky Center, Columbia University, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Dubey+S%22">Dubey S</searchLink>; Mailman School of Public Health, Columbia University, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Nandakumar+R%22">Nandakumar R</searchLink>; Mailman School of Public Health, Columbia University, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Lee+AJ%22">Lee AJ</searchLink>; The Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, New York, USA.; Gertrude H. Sergievsky Center, Columbia University, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Lantigua+RA%22">Lantigua RA</searchLink>; Vagelos College of Physicians and Surgeons, Columbia University, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Medrano+M%22">Medrano M</searchLink>; Pontificia Universidad Católica Madre y Maestra, Santiago, República Dominicana.<br /><searchLink fieldCode="AU" term="%22Mejia+DR%22">Mejia DR</searchLink>; CEDIMAT, Plaza de la Salud, Dr. Juan Manuel Taveras Rodríguez C/Pepillo Salcedo esq. Arturo Logroño, Santo Domingo, República Dominicana.; Universidad Nacional Pedro Henriquez Ureña, Santo Domingo, República Dominicana.<br /><searchLink fieldCode="AU" term="%22Honig+LS%22">Honig LS</searchLink>; The Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, New York, USA.; Gertrude H. Sergievsky Center, Columbia University, New York, New York, USA.; Vagelos College of Physicians and Surgeons, Columbia University, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Dalgard+CL%22">Dalgard CL</searchLink>; Department of Anatomy, Physiology and Genetics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.; The American Genome Center, Center for Military Precision Health, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Miller+GW%22">Miller GW</searchLink>; Mailman School of Public Health, Columbia University, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Mayeux+R%22">Mayeux R</searchLink>; The Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, New York, USA.; Gertrude H. Sergievsky Center, Columbia University, New York, New York, USA.; Vagelos College of Physicians and Surgeons, Columbia University, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Vardarajan+BN%22">Vardarajan BN</searchLink>; The Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, New York, USA.; Gertrude H. Sergievsky Center, Columbia University, New York, New York, USA.; Vagelos College of Physicians and Surgeons, Columbia University, New York, New York, USA.
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