CD21 primes extrafollicular differentiation of autoreactive B cells in a TLR7-driven lupus model.
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| Title: | CD21 primes extrafollicular differentiation of autoreactive B cells in a TLR7-driven lupus model. |
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| Authors: | Zhu DY; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Harvard Medical School, Boston, USA.; Harvard Graduate Program in Virology, Boston, USA.; Department of Microbiology, Harvard Medical School, Boston, USA., Maurer DP; Harvard Graduate Program in Virology, Boston, USA.; Department of Microbiology, Harvard Medical School, Boston, USA.; Ragon Institute of Mass General, MIT, and Harvard, Cambridge, USA., Castrillon C; Department of Medicine, Emory University School of Medicine, Atlanta, USA., Deng Y; Ragon Institute of Mass General, MIT, and Harvard, Cambridge, USA., Mohamed FAN; Ragon Institute of Mass General, MIT, and Harvard, Cambridge, USA., Ma M; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Harvard Medical School, Boston, USA., Tang D; Pfizer Centers for Therapeutic Innovation, Boston, USA., Min-Debartolo J; Pfizer Centers for Therapeutic Innovation, Boston, USA., Higginson-Scott N; Pfizer Centers for Therapeutic Innovation, Boston, USA., Buhlmann J; Pfizer Centers for Therapeutic Innovation, Boston, USA., Schmidt AG; Department of Microbiology, Harvard Medical School, Boston, USA.; Ragon Institute of Mass General, MIT, and Harvard, Cambridge, USA., Lingwood D; Ragon Institute of Mass General, MIT, and Harvard, Cambridge, USA., Carroll MC; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Harvard Medical School, Boston, USA.; Department of Pediatrics, Harvard Medical School, Boston, USA. |
| Source: | Science immunology [Sci Immunol] 2025 Nov 14; Vol. 10 (113), pp. eads8226. Date of Electronic Publication: 2025 Nov 14. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101688624 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2470-9468 (Electronic) Linking ISSN: 24709468 NLM ISO Abbreviation: Sci Immunol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2470-9468 |
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| DOI: | 10.1126/sciimmunol.ads8226 |
