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CD21 primes extrafollicular differentiation of autoreactive B cells in a TLR7-driven lupus model.

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Title: CD21 primes extrafollicular differentiation of autoreactive B cells in a TLR7-driven lupus model.
Authors: Zhu DY; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Harvard Medical School, Boston, USA.; Harvard Graduate Program in Virology, Boston, USA.; Department of Microbiology, Harvard Medical School, Boston, USA., Maurer DP; Harvard Graduate Program in Virology, Boston, USA.; Department of Microbiology, Harvard Medical School, Boston, USA.; Ragon Institute of Mass General, MIT, and Harvard, Cambridge, USA., Castrillon C; Department of Medicine, Emory University School of Medicine, Atlanta, USA., Deng Y; Ragon Institute of Mass General, MIT, and Harvard, Cambridge, USA., Mohamed FAN; Ragon Institute of Mass General, MIT, and Harvard, Cambridge, USA., Ma M; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Harvard Medical School, Boston, USA., Tang D; Pfizer Centers for Therapeutic Innovation, Boston, USA., Min-Debartolo J; Pfizer Centers for Therapeutic Innovation, Boston, USA., Higginson-Scott N; Pfizer Centers for Therapeutic Innovation, Boston, USA., Buhlmann J; Pfizer Centers for Therapeutic Innovation, Boston, USA., Schmidt AG; Department of Microbiology, Harvard Medical School, Boston, USA.; Ragon Institute of Mass General, MIT, and Harvard, Cambridge, USA., Lingwood D; Ragon Institute of Mass General, MIT, and Harvard, Cambridge, USA., Carroll MC; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Harvard Medical School, Boston, USA.; Department of Pediatrics, Harvard Medical School, Boston, USA.
Source: Science immunology [Sci Immunol] 2025 Nov 14; Vol. 10 (113), pp. eads8226. Date of Electronic Publication: 2025 Nov 14.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101688624 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2470-9468 (Electronic) Linking ISSN: 24709468 NLM ISO Abbreviation: Sci Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: CD21 primes extrafollicular differentiation of autoreactive B cells in a TLR7-driven lupus model.
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  Data: <searchLink fieldCode="AU" term="%22Zhu+DY%22">Zhu DY</searchLink>; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Harvard Medical School, Boston, USA.; Harvard Graduate Program in Virology, Boston, USA.; Department of Microbiology, Harvard Medical School, Boston, USA.<br /><searchLink fieldCode="AU" term="%22Maurer+DP%22">Maurer DP</searchLink>; Harvard Graduate Program in Virology, Boston, USA.; Department of Microbiology, Harvard Medical School, Boston, USA.; Ragon Institute of Mass General, MIT, and Harvard, Cambridge, USA.<br /><searchLink fieldCode="AU" term="%22Castrillon+C%22">Castrillon C</searchLink>; Department of Medicine, Emory University School of Medicine, Atlanta, USA.<br /><searchLink fieldCode="AU" term="%22Deng+Y%22">Deng Y</searchLink>; Ragon Institute of Mass General, MIT, and Harvard, Cambridge, USA.<br /><searchLink fieldCode="AU" term="%22Mohamed+FAN%22">Mohamed FAN</searchLink>; Ragon Institute of Mass General, MIT, and Harvard, Cambridge, USA.<br /><searchLink fieldCode="AU" term="%22Ma+M%22">Ma M</searchLink>; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Harvard Medical School, Boston, USA.<br /><searchLink fieldCode="AU" term="%22Tang+D%22">Tang D</searchLink>; Pfizer Centers for Therapeutic Innovation, Boston, USA.<br /><searchLink fieldCode="AU" term="%22Min-Debartolo+J%22">Min-Debartolo J</searchLink>; Pfizer Centers for Therapeutic Innovation, Boston, USA.<br /><searchLink fieldCode="AU" term="%22Higginson-Scott+N%22">Higginson-Scott N</searchLink>; Pfizer Centers for Therapeutic Innovation, Boston, USA.<br /><searchLink fieldCode="AU" term="%22Buhlmann+J%22">Buhlmann J</searchLink>; Pfizer Centers for Therapeutic Innovation, Boston, USA.<br /><searchLink fieldCode="AU" term="%22Schmidt+AG%22">Schmidt AG</searchLink>; Department of Microbiology, Harvard Medical School, Boston, USA.; Ragon Institute of Mass General, MIT, and Harvard, Cambridge, USA.<br /><searchLink fieldCode="AU" term="%22Lingwood+D%22">Lingwood D</searchLink>; Ragon Institute of Mass General, MIT, and Harvard, Cambridge, USA.<br /><searchLink fieldCode="AU" term="%22Carroll+MC%22">Carroll MC</searchLink>; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Harvard Medical School, Boston, USA.; Department of Pediatrics, Harvard Medical School, Boston, USA.
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  Data: <searchLink fieldCode="JN" term="%22101688624%22">Science immunology</searchLink> [Sci Immunol] 2025 Nov 14; Vol. 10 (113), pp. eads8226. <i>Date of Electronic Publication: </i>2025 Nov 14.
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