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Integrating Pharmacogenomic Insights in GLP-1 Receptor Agonist Therapy: Direct GLP1R and ARRB1 Variants and Indirect CYP2D6 Influences in Personalized Obesity Management.

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Title: Integrating Pharmacogenomic Insights in GLP-1 Receptor Agonist Therapy: Direct GLP1R and ARRB1 Variants and Indirect CYP2D6 Influences in Personalized Obesity Management.
Authors: Jayathilaka NS; Department of Pharmacy and Pharmaceutical Sciences, University of Sri Jayewardenepura, Gangodawila, Nugegoda, Sri Lanka., Weththasinghe AV; Department of Biomedical Sciences, Faculty of Health Sciences, KIU, Battaramulla, Sri Lanka., Ganamurali N; Helix Research Lab, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai, Tamil Nadu, India., Sabarathinam S; Helix Research Lab, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai, Tamil Nadu, India.
Source: Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2026 Mar; Vol. 15 (3), pp. e1624. Date of Electronic Publication: 2025 Nov 14.
Publication Type: Journal Article; Review; Systematic Review
Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 101572899 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2160-7648 (Electronic) Linking ISSN: 2160763X NLM ISO Abbreviation: Clin Pharmacol Drug Dev Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Integrating Pharmacogenomic Insights in GLP-1 Receptor Agonist Therapy: Direct GLP1R and ARRB1 Variants and Indirect CYP2D6 Influences in Personalized Obesity Management.
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  Data: <searchLink fieldCode="AU" term="%22Jayathilaka+NS%22">Jayathilaka NS</searchLink>; Department of Pharmacy and Pharmaceutical Sciences, University of Sri Jayewardenepura, Gangodawila, Nugegoda, Sri Lanka.<br /><searchLink fieldCode="AU" term="%22Weththasinghe+AV%22">Weththasinghe AV</searchLink>; Department of Biomedical Sciences, Faculty of Health Sciences, KIU, Battaramulla, Sri Lanka.<br /><searchLink fieldCode="AU" term="%22Ganamurali+N%22">Ganamurali N</searchLink>; Helix Research Lab, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai, Tamil Nadu, India.<br /><searchLink fieldCode="AU" term="%22Sabarathinam+S%22">Sabarathinam S</searchLink>; Helix Research Lab, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai, Tamil Nadu, India.
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  Data: <searchLink fieldCode="JN" term="%22101572899%22">Clinical pharmacology in drug development</searchLink> [Clin Pharmacol Drug Dev] 2026 Mar; Vol. 15 (3), pp. e1624. <i>Date of Electronic Publication: </i>2025 Nov 14.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley%22">Wiley </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101572899 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2160-7648 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%222160763X%22">2160763X </searchLink><i>NLM ISO Abbreviation: </i>Clin Pharmacol Drug Dev <i>Subsets: </i>MEDLINE
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        Value: 10.1002/cpdd.1624
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      – Code: eng
        Text: English
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      – TitleFull: Integrating Pharmacogenomic Insights in GLP-1 Receptor Agonist Therapy: Direct GLP1R and ARRB1 Variants and Indirect CYP2D6 Influences in Personalized Obesity Management.
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              Text: 2026 Mar
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