Sex-dependent modulation of PCB-mediated toxicity from a proteomic and microbiome perspective.

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Title: Sex-dependent modulation of PCB-mediated toxicity from a proteomic and microbiome perspective.
Authors: Singhal R; Center for Cardiometabolic Science, University of Louisville, Louisville, KY, 40202, USA.; KY INBRE Bioinformatics Core, University of Louisville, Louisville, KY, 40202, USA., Qaissi Z; Department of Medicine, Division of Gastroenterology,, University of Louisville School of, Medicine Hepatology & Nutrition, Kosair Charities Clinical and Translational Research Building, 505 S. Hancock St., Louisville, KY, 40202, USA., Zheng H; Center for Integrative Environmental Health Sciences, University of Louisville, Louisville, KY, 40202, USA., Hua Y; Department of Medicine, Division of Gastroenterology,, University of Louisville School of, Medicine Hepatology & Nutrition, Kosair Charities Clinical and Translational Research Building, 505 S. Hancock St., Louisville, KY, 40202, USA., Hardesty JE; Department of Pharmacology & Toxicology, School of Medicine, University of Louisville, Louisville, KY, 40202, USA.; The Hepatobiology and Toxicology Center, University of Louisville, Louisville, KY, 40202, USA., Rouchka EC; KY INBRE Bioinformatics Core, University of Louisville, Louisville, KY, 40202, USA., Merchant ML; Center for Integrative Environmental Health Sciences, University of Louisville, Louisville, KY, 40202, USA.; Kidney Disease Program and Clinical Proteomics Center, University of Louisville, Louisville, KY, 40202, USA., Kong M; Center for Integrative Environmental Health Sciences, University of Louisville, Louisville, KY, 40202, USA.; Department of Bioinformatics and Biostatistics, School of Public Health and Information Sciences, University of Louisville, Louisville, KY, 40202, USA.; Biostatistics Shared Facility, James Graham Brown Cancer Center, School of Medicine, University of Louisville, Louisville, KY, 40202, USA., Wahlang B; Department of Medicine, Division of Gastroenterology,, University of Louisville School of, Medicine Hepatology & Nutrition, Kosair Charities Clinical and Translational Research Building, 505 S. Hancock St., Louisville, KY, 40202, USA. banrida.wahlang@louisville.edu.; Center for Integrative Environmental Health Sciences, University of Louisville, Louisville, KY, 40202, USA. banrida.wahlang@louisville.edu.; Department of Pharmacology & Toxicology, School of Medicine, University of Louisville, Louisville, KY, 40202, USA. banrida.wahlang@louisville.edu.; The Hepatobiology and Toxicology Center, University of Louisville, Louisville, KY, 40202, USA. banrida.wahlang@louisville.edu.; Superfund Research Center, University of Louisville, Louisville, KY, 40202, USA. banrida.wahlang@louisville.edu.
Source: Scientific reports [Sci Rep] 2025 Nov 14; Vol. 15 (1), pp. 39903. Date of Electronic Publication: 2025 Nov 14.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Singhal+R%22">Singhal R</searchLink>; Center for Cardiometabolic Science, University of Louisville, Louisville, KY, 40202, USA.; KY INBRE Bioinformatics Core, University of Louisville, Louisville, KY, 40202, USA.<br /><searchLink fieldCode="AU" term="%22Qaissi+Z%22">Qaissi Z</searchLink>; Department of Medicine, Division of Gastroenterology,, University of Louisville School of, Medicine Hepatology & Nutrition, Kosair Charities Clinical and Translational Research Building, 505 S. Hancock St., Louisville, KY, 40202, USA.<br /><searchLink fieldCode="AU" term="%22Zheng+H%22">Zheng H</searchLink>; Center for Integrative Environmental Health Sciences, University of Louisville, Louisville, KY, 40202, USA.<br /><searchLink fieldCode="AU" term="%22Hua+Y%22">Hua Y</searchLink>; Department of Medicine, Division of Gastroenterology,, University of Louisville School of, Medicine Hepatology & Nutrition, Kosair Charities Clinical and Translational Research Building, 505 S. Hancock St., Louisville, KY, 40202, USA.<br /><searchLink fieldCode="AU" term="%22Hardesty+JE%22">Hardesty JE</searchLink>; Department of Pharmacology & Toxicology, School of Medicine, University of Louisville, Louisville, KY, 40202, USA.; The Hepatobiology and Toxicology Center, University of Louisville, Louisville, KY, 40202, USA.<br /><searchLink fieldCode="AU" term="%22Rouchka+EC%22">Rouchka EC</searchLink>; KY INBRE Bioinformatics Core, University of Louisville, Louisville, KY, 40202, USA.<br /><searchLink fieldCode="AU" term="%22Merchant+ML%22">Merchant ML</searchLink>; Center for Integrative Environmental Health Sciences, University of Louisville, Louisville, KY, 40202, USA.; Kidney Disease Program and Clinical Proteomics Center, University of Louisville, Louisville, KY, 40202, USA.<br /><searchLink fieldCode="AU" term="%22Kong+M%22">Kong M</searchLink>; Center for Integrative Environmental Health Sciences, University of Louisville, Louisville, KY, 40202, USA.; Department of Bioinformatics and Biostatistics, School of Public Health and Information Sciences, University of Louisville, Louisville, KY, 40202, USA.; Biostatistics Shared Facility, James Graham Brown Cancer Center, School of Medicine, University of Louisville, Louisville, KY, 40202, USA.<br /><searchLink fieldCode="AU" term="%22Wahlang+B%22">Wahlang B</searchLink>; Department of Medicine, Division of Gastroenterology,, University of Louisville School of, Medicine Hepatology & Nutrition, Kosair Charities Clinical and Translational Research Building, 505 S. Hancock St., Louisville, KY, 40202, USA. banrida.wahlang@louisville.edu.; Center for Integrative Environmental Health Sciences, University of Louisville, Louisville, KY, 40202, USA. banrida.wahlang@louisville.edu.; Department of Pharmacology & Toxicology, School of Medicine, University of Louisville, Louisville, KY, 40202, USA. banrida.wahlang@louisville.edu.; The Hepatobiology and Toxicology Center, University of Louisville, Louisville, KY, 40202, USA. banrida.wahlang@louisville.edu.; Superfund Research Center, University of Louisville, Louisville, KY, 40202, USA. banrida.wahlang@louisville.edu.
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