First-line treatment efficacy of anti-EGFR versus anti-VEGF antibodies in BRAFV600E-mutated metastatic colorectal cancer according to primary tumor sidedness: A pooled analysis of seven clinical trials performed in the first-line treatment of mCRC (German AIO Study Group).
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| Title: | First-line treatment efficacy of anti-EGFR versus anti-VEGF antibodies in BRAFV600E-mutated metastatic colorectal cancer according to primary tumor sidedness: A pooled analysis of seven clinical trials performed in the first-line treatment of mCRC (German AIO Study Group). |
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| Authors: | Weiss L; Department of Medicine III and Comprehensive Cancer Center (CCC Munich LMU), University Hospital, LMU Munich, Munich, Germany. Electronic address: Lena.Weiss@med.uni-muenchen.de., Stintzing S; Department of Hematology, Oncology and Cancer Immunology (CCM), Charité-Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany; DKTK Heidelberg, Partner Site Berlin, Germany., Modest DP; Department of Hematology, Oncology and Cancer Immunology (CCM), Charité-Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany., Stahler A; Department of Hematology, Oncology and Cancer Immunology (CCM), Charité-Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany., von Weikersthal LF; MVZ Gesundheitszentrum St. Marien GmbH, Amberg, Germany., Reinacher-Schick A; Department of Hematology, Oncology and Palliative Care, St. Josef-Hospital, Ruhr-University Bochum, Bochum, Germany., Decker T; Onkologie Ravensburg, Ravensburg, Germany., Probst V; Department of Medicine III and Comprehensive Cancer Center (CCC Munich LMU), University Hospital, LMU Munich, Munich, Germany., Heinrich K; Department of Medicine III and Comprehensive Cancer Center (CCC Munich LMU), University Hospital, LMU Munich, Munich, Germany., Schwaner I; Onkologische Schwerpunktpraxis Kurfürstendamm, Berlin, Germany., Kaiser F; VK&K Oncology GmbH, Landshut, Germany., Pihusch R; MVZ Praxis Pihusch, Rosenheim, Germany., Fuchs M; München Klinik Bogenhausen, Department of Gastroenterology, Hepatology and Gastrointestinal Oncology, Munich, Germany., Held S; ClinAssess GmbH, Leverkusen, Germany., Alig A; Department of Hematology, Oncology and Cancer Immunology (CCM), Charité-Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany., Gruenberger B; Universitätsklinikum Wiener Neustadt, Wiener Neustadt, Austria., Prager GW; Medical University of Vienna, Department of Medicine I, Vienna, Austria., Tougeron D; Department of Hepato-Gastroenterology, Poitiers University Hospital and University of Poitiers, Poitiers, France., Taieb J; CARPEM comprehensive cancer center, University Paris-Cité, department of Gastroenterology and GI Oncology, Hôpital Européen Georges Pompidou, Paris, France., Heinemann V; Department of Medicine III and Comprehensive Cancer Center (CCC Munich LMU), University Hospital, LMU Munich, Munich, Germany. |
| Source: | European journal of cancer (Oxford, England : 1990) [Eur J Cancer] 2026 Jan; Vol. 232, pp. 116105. Date of Electronic Publication: 2025 Nov 13. |
| Publication Type: | Comparative Study; Journal Article; Meta-Analysis; Comparative Study |
| Journal Info: | Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9005373 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0852 (Electronic) Linking ISSN: 09598049 NLM ISO Abbreviation: Eur J Cancer Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41240527 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: First-line treatment efficacy of anti-EGFR versus anti-VEGF antibodies in BRAF<superscript>V600E</superscript>-mutated metastatic colorectal cancer according to primary tumor sidedness: A pooled analysis of seven clinical trials performed in the first-line treatment of mCRC (German AIO Study Group). – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Weiss+L%22">Weiss L</searchLink>; Department of Medicine III and Comprehensive Cancer Center (CCC Munich LMU), University Hospital, LMU Munich, Munich, Germany. Electronic address: Lena.Weiss@med.uni-muenchen.de.<br /><searchLink fieldCode="AU" term="%22Stintzing+S%22">Stintzing S</searchLink>; Department of Hematology, Oncology and Cancer Immunology (CCM), Charité-Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany; DKTK Heidelberg, Partner Site Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Modest+DP%22">Modest DP</searchLink>; Department of Hematology, Oncology and Cancer Immunology (CCM), Charité-Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Stahler+A%22">Stahler A</searchLink>; Department of Hematology, Oncology and Cancer Immunology (CCM), Charité-Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22von+Weikersthal+LF%22">von Weikersthal LF</searchLink>; MVZ Gesundheitszentrum St. Marien GmbH, Amberg, Germany.<br /><searchLink fieldCode="AU" term="%22Reinacher-Schick+A%22">Reinacher-Schick A</searchLink>; Department of Hematology, Oncology and Palliative Care, St. Josef-Hospital, Ruhr-University Bochum, Bochum, Germany.<br /><searchLink fieldCode="AU" term="%22Decker+T%22">Decker T</searchLink>; Onkologie Ravensburg, Ravensburg, Germany.<br /><searchLink fieldCode="AU" term="%22Probst+V%22">Probst V</searchLink>; Department of Medicine III and Comprehensive Cancer Center (CCC Munich LMU), University Hospital, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Heinrich+K%22">Heinrich K</searchLink>; Department of Medicine III and Comprehensive Cancer Center (CCC Munich LMU), University Hospital, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Schwaner+I%22">Schwaner I</searchLink>; Onkologische Schwerpunktpraxis Kurfürstendamm, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Kaiser+F%22">Kaiser F</searchLink>; VK&K Oncology GmbH, Landshut, Germany.<br /><searchLink fieldCode="AU" term="%22Pihusch+R%22">Pihusch R</searchLink>; MVZ Praxis Pihusch, Rosenheim, Germany.<br /><searchLink fieldCode="AU" term="%22Fuchs+M%22">Fuchs M</searchLink>; München Klinik Bogenhausen, Department of Gastroenterology, Hepatology and Gastrointestinal Oncology, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Held+S%22">Held S</searchLink>; ClinAssess GmbH, Leverkusen, Germany.<br /><searchLink fieldCode="AU" term="%22Alig+A%22">Alig A</searchLink>; Department of Hematology, Oncology and Cancer Immunology (CCM), Charité-Universitätsmedizin Berlin, Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Gruenberger+B%22">Gruenberger B</searchLink>; Universitätsklinikum Wiener Neustadt, Wiener Neustadt, Austria.<br /><searchLink fieldCode="AU" term="%22Prager+GW%22">Prager GW</searchLink>; Medical University of Vienna, Department of Medicine I, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Tougeron+D%22">Tougeron D</searchLink>; Department of Hepato-Gastroenterology, Poitiers University Hospital and University of Poitiers, Poitiers, France.<br /><searchLink fieldCode="AU" term="%22Taieb+J%22">Taieb J</searchLink>; CARPEM comprehensive cancer center, University Paris-Cité, department of Gastroenterology and GI Oncology, Hôpital Européen Georges Pompidou, Paris, France.<br /><searchLink fieldCode="AU" term="%22Heinemann+V%22">Heinemann V</searchLink>; Department of Medicine III and Comprehensive Cancer Center (CCC Munich LMU), University Hospital, LMU Munich, Munich, Germany. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%229005373%22">European journal of cancer (Oxford, England : 1990)</searchLink> [Eur J Cancer] 2026 Jan; Vol. 232, pp. 116105. <i>Date of Electronic Publication: </i>2025 Nov 13. – Name: TypePub Label: Publication Type Group: TypPub Data: Comparative Study; Journal Article; Meta-Analysis; Comparative Study – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science+Ltd%22">Elsevier Science Ltd </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9005373 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1879-0852 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209598049%22">09598049 </searchLink><i>NLM ISO Abbreviation: </i>Eur J Cancer <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41240527 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.ejca.2025.116105 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 116105 Titles: – TitleFull: First-line treatment efficacy of anti-EGFR versus anti-VEGF antibodies in BRAFV600E-mutated metastatic colorectal cancer according to primary tumor sidedness: A pooled analysis of seven clinical trials performed in the first-line treatment of mCRC (German AIO Study Group). Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Weiss L – PersonEntity: Name: NameFull: Stintzing S – PersonEntity: Name: NameFull: Modest DP – PersonEntity: Name: NameFull: Stahler A – PersonEntity: Name: NameFull: von Weikersthal LF – PersonEntity: Name: NameFull: Reinacher-Schick A – PersonEntity: Name: NameFull: Decker T – PersonEntity: Name: NameFull: Probst V – PersonEntity: Name: NameFull: Heinrich K – PersonEntity: Name: NameFull: Schwaner I – PersonEntity: Name: NameFull: Kaiser F – PersonEntity: Name: NameFull: Pihusch R – PersonEntity: Name: NameFull: Fuchs M – PersonEntity: Name: NameFull: Held S – PersonEntity: Name: NameFull: Alig A – PersonEntity: Name: NameFull: Gruenberger B – PersonEntity: Name: NameFull: Prager GW – PersonEntity: Name: NameFull: Tougeron D – PersonEntity: Name: NameFull: Taieb J – PersonEntity: Name: NameFull: Heinemann V IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 01 Text: 2026 Jan Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1879-0852 Numbering: – Type: volume Value: 232 Titles: – TitleFull: European journal of cancer (Oxford, England : 1990) Type: main |
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