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Exploiting Metabolic Vulnerabilities in Cancer with a Dual-Transporter-Targeted 2-Deoxyglucose Analogue for Low-Dose, Potent Antitumor Activity.

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Title: Exploiting Metabolic Vulnerabilities in Cancer with a Dual-Transporter-Targeted 2-Deoxyglucose Analogue for Low-Dose, Potent Antitumor Activity.
Authors: Jeon S; Department of Chemistry, The University of Texas at Austin, Austin, Texas 78703, United States., Qin X; Department of Chemistry, The University of Texas at Austin, Austin, Texas 78703, United States., Hildebrand MA; Department of Chemistry, The University of Texas at Austin, Austin, Texas 78703, United States., Odom TL; Department of Chemistry, The University of Texas at Austin, Austin, Texas 78703, United States., Zamborini I; Department of Chemistry, The University of Texas at Austin, Austin, Texas 78703, United States., Patel R; Department of Chemistry, The University of Texas at Austin, Austin, Texas 78703, United States., Liu X; Department of Chemistry, The University of Texas at Austin, Austin, Texas 78703, United States., Seo C; Department of Chemistry, The University of Texas at Austin, Austin, Texas 78703, United States., Callmann CE; Department of Chemistry, The University of Texas at Austin, Austin, Texas 78703, United States.
Source: Journal of the American Chemical Society [J Am Chem Soc] 2025 Nov 26; Vol. 147 (47), pp. 43267-43272. Date of Electronic Publication: 2025 Nov 17.
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5126 (Electronic) Linking ISSN: 00027863 NLM ISO Abbreviation: J Am Chem Soc Subsets: MEDLINE
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              Text: 2025 Nov 26
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