Bimekizumab demonstrated a favorable safety profile and high levels of efficacy with up to 2 years of treatment in patients with moderate to severe hidradenitis suppurativa: Pooled results from two phase 3 randomized, controlled trials and their open-label extension.
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| Title: | Bimekizumab demonstrated a favorable safety profile and high levels of efficacy with up to 2 years of treatment in patients with moderate to severe hidradenitis suppurativa: Pooled results from two phase 3 randomized, controlled trials and their open-label extension. |
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| Authors: | Sayed CJ; Department of Dermatology, University of North Carolina School of Medicine, Chapel Hill, North Carolina; European Hidradenitis Suppurativa Foundation (EHSF) e.V., Dessau, Germany. Electronic address: christopher_sayed@med.unc.edu., Kirby B; European Hidradenitis Suppurativa Foundation (EHSF) e.V., Dessau, Germany; St Vincent's University Hospital, Elm Park and the Charles Institute, University College Dublin, Dublin, Republic of Ireland., Garg A; Department of Dermatology, Northwell, New Hyde Park, New York., Naik HB; Department of Dermatology, University of California, San Francisco, California., Kimball AB; Department of Dermatology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts., Zouboulis CC; European Hidradenitis Suppurativa Foundation (EHSF) e.V., Dessau, Germany; Departments of Dermatology, Venereology, Allergology and Immunology, Staedtisches Klinikum Dessau, Brandenburg Medical School Theodor Fontane and Faculty of Health Sciences Brandenburg, Dessau, Germany., Jemec GBE; European Hidradenitis Suppurativa Foundation (EHSF) e.V., Dessau, Germany; Department of Dermatology, Herlev-Gentofte Hospital, University Hospital, Herlev, Denmark; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Kokolakis G; Psoriasis Research and Treatment Center, Clinic of Dermatology, Venereology, and Allergology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany., Ingram JR; European Hidradenitis Suppurativa Foundation (EHSF) e.V., Dessau, Germany; Department of Dermatology & Academic Wound Healing, Division of Infection and Immunity, Cardiff University, Cardiff, UK., Morita A; Department of Geriatric and Environmental Dermatology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan., Deherder D; UCB, Braine-l'Alleud, Belgium., Crater C; UCB, Morrisville, North Carolina., Rolleri RL; UCB, Morrisville, North Carolina., Vaux T; UCB, Slough, UK., Lambert J; UCB, Colombes, France., Lukowski B; Vedim/UCB, Warsaw, Poland., Bechara FG; Department of Dermatology, Venereology, and Allergology, St. Josef-Hospital, Ruhr-University Bochum, Bochum, Germany; Department of Dermatology, ICH - International Center for Hidradenitis Suppurativa/Acne Inversa, Ruhr-University Bochum, Bochum, Germany. |
| Source: | Journal of the American Academy of Dermatology [J Am Acad Dermatol] 2026 Mar; Vol. 94 (3), pp. 867-878. Date of Electronic Publication: 2025 Nov 15. |
| Publication Type: | Journal Article; Clinical Trial, Phase III; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Mosby Country of Publication: United States NLM ID: 7907132 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6787 (Electronic) Linking ISSN: 01909622 NLM ISO Abbreviation: J Am Acad Dermatol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41248770 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Bimekizumab demonstrated a favorable safety profile and high levels of efficacy with up to 2 years of treatment in patients with moderate to severe hidradenitis suppurativa: Pooled results from two phase 3 randomized, controlled trials and their open-label extension. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Sayed+CJ%22">Sayed CJ</searchLink>; Department of Dermatology, University of North Carolina School of Medicine, Chapel Hill, North Carolina; European Hidradenitis Suppurativa Foundation (EHSF) e.V., Dessau, Germany. Electronic address: christopher&#95;sayed@med.unc.edu.<br /><searchLink fieldCode="AU" term="%22Kirby+B%22">Kirby B</searchLink>; European Hidradenitis Suppurativa Foundation (EHSF) e.V., Dessau, Germany; St Vincent's University Hospital, Elm Park and the Charles Institute, University College Dublin, Dublin, Republic of Ireland.<br /><searchLink fieldCode="AU" term="%22Garg+A%22">Garg A</searchLink>; Department of Dermatology, Northwell, New Hyde Park, New York.<br /><searchLink fieldCode="AU" term="%22Naik+HB%22">Naik HB</searchLink>; Department of Dermatology, University of California, San Francisco, California.<br /><searchLink fieldCode="AU" term="%22Kimball+AB%22">Kimball AB</searchLink>; Department of Dermatology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Zouboulis+CC%22">Zouboulis CC</searchLink>; European Hidradenitis Suppurativa Foundation (EHSF) e.V., Dessau, Germany; Departments of Dermatology, Venereology, Allergology and Immunology, Staedtisches Klinikum Dessau, Brandenburg Medical School Theodor Fontane and Faculty of Health Sciences Brandenburg, Dessau, Germany.<br /><searchLink fieldCode="AU" term="%22Jemec+GBE%22">Jemec GBE</searchLink>; European Hidradenitis Suppurativa Foundation (EHSF) e.V., Dessau, Germany; Department of Dermatology, Herlev-Gentofte Hospital, University Hospital, Herlev, Denmark; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Kokolakis+G%22">Kokolakis G</searchLink>; Psoriasis Research and Treatment Center, Clinic of Dermatology, Venereology, and Allergology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Ingram+JR%22">Ingram JR</searchLink>; European Hidradenitis Suppurativa Foundation (EHSF) e.V., Dessau, Germany; Department of Dermatology & Academic Wound Healing, Division of Infection and Immunity, Cardiff University, Cardiff, UK.<br /><searchLink fieldCode="AU" term="%22Morita+A%22">Morita A</searchLink>; Department of Geriatric and Environmental Dermatology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.<br /><searchLink fieldCode="AU" term="%22Deherder+D%22">Deherder D</searchLink>; UCB, Braine-l'Alleud, Belgium.<br /><searchLink fieldCode="AU" term="%22Crater+C%22">Crater C</searchLink>; UCB, Morrisville, North Carolina.<br /><searchLink fieldCode="AU" term="%22Rolleri+RL%22">Rolleri RL</searchLink>; UCB, Morrisville, North Carolina.<br /><searchLink fieldCode="AU" term="%22Vaux+T%22">Vaux T</searchLink>; UCB, Slough, UK.<br /><searchLink fieldCode="AU" term="%22Lambert+J%22">Lambert J</searchLink>; UCB, Colombes, France.<br /><searchLink fieldCode="AU" term="%22Lukowski+B%22">Lukowski B</searchLink>; Vedim/UCB, Warsaw, Poland.<br /><searchLink fieldCode="AU" term="%22Bechara+FG%22">Bechara FG</searchLink>; Department of Dermatology, Venereology, and Allergology, St. Josef-Hospital, Ruhr-University Bochum, Bochum, Germany; Department of Dermatology, ICH - International Center for Hidradenitis Suppurativa/Acne Inversa, Ruhr-University Bochum, Bochum, Germany. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%227907132%22">Journal of the American Academy of Dermatology</searchLink> [J Am Acad Dermatol] 2026 Mar; Vol. 94 (3), pp. 867-878. <i>Date of Electronic Publication: </i>2025 Nov 15. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Clinical Trial, Phase III; Randomized Controlled Trial; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Mosby%22">Mosby </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7907132 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1097-6787 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201909622%22">01909622 </searchLink><i>NLM ISO Abbreviation: </i>J Am Acad Dermatol <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41248770 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.jaad.2025.11.031 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 867 Titles: – TitleFull: Bimekizumab demonstrated a favorable safety profile and high levels of efficacy with up to 2 years of treatment in patients with moderate to severe hidradenitis suppurativa: Pooled results from two phase 3 randomized, controlled trials and their open-label extension. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Sayed CJ – PersonEntity: Name: NameFull: Kirby B – PersonEntity: Name: NameFull: Garg A – PersonEntity: Name: NameFull: Naik HB – PersonEntity: Name: NameFull: Kimball AB – PersonEntity: Name: NameFull: Zouboulis CC – PersonEntity: Name: NameFull: Jemec GBE – PersonEntity: Name: NameFull: Kokolakis G – PersonEntity: Name: NameFull: Ingram JR – PersonEntity: Name: NameFull: Morita A – PersonEntity: Name: NameFull: Deherder D – PersonEntity: Name: NameFull: Crater C – PersonEntity: Name: NameFull: Rolleri RL – PersonEntity: Name: NameFull: Vaux T – PersonEntity: Name: NameFull: Lambert J – PersonEntity: Name: NameFull: Lukowski B – PersonEntity: Name: NameFull: Bechara FG IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 03 Text: 2026 Mar Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1097-6787 Numbering: – Type: volume Value: 94 – Type: issue Value: 3 Titles: – TitleFull: Journal of the American Academy of Dermatology Type: main |
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