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Preclinical pharmacology, pharmacokinetics, and pharmacodynamics of veligrotug, a full antagonist antibody to the IGF-1 receptor in development for thyroid eye disease.

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Title: Preclinical pharmacology, pharmacokinetics, and pharmacodynamics of veligrotug, a full antagonist antibody to the IGF-1 receptor in development for thyroid eye disease.
Authors: Kaplan R; Department of Research, Viridian Therapeutics, Inc., Waltham, MA, USA., Zhao Y; Department of Research, Viridian Therapeutics, Inc., Waltham, MA, USA., Tsai J; Department of Research, Viridian Therapeutics, Inc., Waltham, MA, USA., Dickinson B; Department of Research, Viridian Therapeutics, Inc., Waltham, MA, USA., Swanson T; Department of Research, Viridian Therapeutics, Inc., Waltham, MA, USA., Foster K; Department of Research, Viridian Therapeutics, Inc., Waltham, MA, USA., Bedian V; Department of Research, Viridian Therapeutics, Inc., Waltham, MA, USA.
Source: MAbs [MAbs] 2025 Dec; Vol. 17 (1), pp. 2585616. Date of Electronic Publication: 2025 Nov 17.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101479829 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1942-0870 (Electronic) Linking ISSN: 19420862 NLM ISO Abbreviation: MAbs Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Preclinical pharmacology, pharmacokinetics, and pharmacodynamics of veligrotug, a full antagonist antibody to the IGF-1 receptor in development for thyroid eye disease.
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  Data: <searchLink fieldCode="AU" term="%22Kaplan+R%22">Kaplan R</searchLink>; Department of Research, Viridian Therapeutics, Inc., Waltham, MA, USA.<br /><searchLink fieldCode="AU" term="%22Zhao+Y%22">Zhao Y</searchLink>; Department of Research, Viridian Therapeutics, Inc., Waltham, MA, USA.<br /><searchLink fieldCode="AU" term="%22Tsai+J%22">Tsai J</searchLink>; Department of Research, Viridian Therapeutics, Inc., Waltham, MA, USA.<br /><searchLink fieldCode="AU" term="%22Dickinson+B%22">Dickinson B</searchLink>; Department of Research, Viridian Therapeutics, Inc., Waltham, MA, USA.<br /><searchLink fieldCode="AU" term="%22Swanson+T%22">Swanson T</searchLink>; Department of Research, Viridian Therapeutics, Inc., Waltham, MA, USA.<br /><searchLink fieldCode="AU" term="%22Foster+K%22">Foster K</searchLink>; Department of Research, Viridian Therapeutics, Inc., Waltham, MA, USA.<br /><searchLink fieldCode="AU" term="%22Bedian+V%22">Bedian V</searchLink>; Department of Research, Viridian Therapeutics, Inc., Waltham, MA, USA.
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