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The adhesion GPCR ADGRL2 engages Gα13 to enable epidermal differentiation.

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Title: The adhesion GPCR ADGRL2 engages Gα13 to enable epidermal differentiation.
Authors: Yang X; Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA 94305.; Program in Cancer Biology, Stanford University, Stanford, CA 94305., He F; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305., Lopez-Pajares V; Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA 94305., Porter DF; Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA 94305., Garbett K; Department of Pharmacology, Vanderbilt Brain Institute, Vanderbilt University, Nashville, TN 37240., Siprashvili Z; Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA 94305., Ducoli L; Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA 94305., Meyers RM; Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA 94305.; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305., Reynolds DL; Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA 94305., Lan Huong Bui D; Department of Pharmacology, Vanderbilt Brain Institute, Vanderbilt University, Nashville, TN 37240., Hong A; Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA 94305., Nguyen DT; Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA 94305., Jing Y; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305.; Department of Pediatrics, Stanford University, Stanford, CA 94305., Mondal S; Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA 94305., Ko L; Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA 94305., Tao S; Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA 94305., Singal B; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305., Sando R; Department of Pharmacology, Vanderbilt Brain Institute, Vanderbilt University, Nashville, TN 37240., Skiniotis G; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305.; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305., Khavari PA; Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA 94305.; Program in Cancer Biology, Stanford University, Stanford, CA 94305.; Veterans Affairs Palo Alto Healthcare System, Palo Alto, CA 94304.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2025 Nov 25; Vol. 122 (47), pp. e2508436122. Date of Electronic Publication: 2025 Nov 18.
Publication Type: Journal Article
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Yang+X%22">Yang X</searchLink>; Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA 94305.; Program in Cancer Biology, Stanford University, Stanford, CA 94305.<br /><searchLink fieldCode="AU" term="%22He+F%22">He F</searchLink>; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305.<br /><searchLink fieldCode="AU" term="%22Lopez-Pajares+V%22">Lopez-Pajares V</searchLink>; Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA 94305.<br /><searchLink fieldCode="AU" term="%22Porter+DF%22">Porter DF</searchLink>; Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA 94305.<br /><searchLink fieldCode="AU" term="%22Garbett+K%22">Garbett K</searchLink>; Department of Pharmacology, Vanderbilt Brain Institute, Vanderbilt University, Nashville, TN 37240.<br /><searchLink fieldCode="AU" term="%22Siprashvili+Z%22">Siprashvili Z</searchLink>; Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA 94305.<br /><searchLink fieldCode="AU" term="%22Ducoli+L%22">Ducoli L</searchLink>; Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA 94305.<br /><searchLink fieldCode="AU" term="%22Meyers+RM%22">Meyers RM</searchLink>; Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA 94305.; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305.<br /><searchLink fieldCode="AU" term="%22Reynolds+DL%22">Reynolds DL</searchLink>; Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA 94305.<br /><searchLink fieldCode="AU" term="%22Lan+Huong+Bui+D%22">Lan Huong Bui D</searchLink>; Department of Pharmacology, Vanderbilt Brain Institute, Vanderbilt University, Nashville, TN 37240.<br /><searchLink fieldCode="AU" term="%22Hong+A%22">Hong A</searchLink>; Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA 94305.<br /><searchLink fieldCode="AU" term="%22Nguyen+DT%22">Nguyen DT</searchLink>; Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA 94305.<br /><searchLink fieldCode="AU" term="%22Jing+Y%22">Jing Y</searchLink>; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305.; Department of Pediatrics, Stanford University, Stanford, CA 94305.<br /><searchLink fieldCode="AU" term="%22Mondal+S%22">Mondal S</searchLink>; Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA 94305.<br /><searchLink fieldCode="AU" term="%22Ko+L%22">Ko L</searchLink>; Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA 94305.<br /><searchLink fieldCode="AU" term="%22Tao+S%22">Tao S</searchLink>; Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA 94305.<br /><searchLink fieldCode="AU" term="%22Singal+B%22">Singal B</searchLink>; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305.<br /><searchLink fieldCode="AU" term="%22Sando+R%22">Sando R</searchLink>; Department of Pharmacology, Vanderbilt Brain Institute, Vanderbilt University, Nashville, TN 37240.<br /><searchLink fieldCode="AU" term="%22Skiniotis+G%22">Skiniotis G</searchLink>; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305.; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305.<br /><searchLink fieldCode="AU" term="%22Khavari+PA%22">Khavari PA</searchLink>; Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA 94305.; Program in Cancer Biology, Stanford University, Stanford, CA 94305.; Veterans Affairs Palo Alto Healthcare System, Palo Alto, CA 94304.
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  Data: <searchLink fieldCode="JN" term="%227505876%22">Proceedings of the National Academy of Sciences of the United States of America</searchLink> [Proc Natl Acad Sci U S A] 2025 Nov 25; Vol. 122 (47), pp. e2508436122. <i>Date of Electronic Publication: </i>2025 Nov 18.
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