The adhesion GPCR ADGRL2 engages Gα13 to enable epidermal differentiation.

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Title: The adhesion GPCR ADGRL2 engages Gα13 to enable epidermal differentiation.
Authors: Yang X; Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA 94305.; Program in Cancer Biology, Stanford University, Stanford, CA 94305., He F; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305., Lopez-Pajares V; Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA 94305., Porter DF; Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA 94305., Garbett K; Department of Pharmacology, Vanderbilt Brain Institute, Vanderbilt University, Nashville, TN 37240., Siprashvili Z; Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA 94305., Ducoli L; Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA 94305., Meyers RM; Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA 94305.; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305., Reynolds DL; Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA 94305., Lan Huong Bui D; Department of Pharmacology, Vanderbilt Brain Institute, Vanderbilt University, Nashville, TN 37240., Hong A; Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA 94305., Nguyen DT; Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA 94305., Jing Y; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305.; Department of Pediatrics, Stanford University, Stanford, CA 94305., Mondal S; Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA 94305., Ko L; Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA 94305., Tao S; Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA 94305., Singal B; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305., Sando R; Department of Pharmacology, Vanderbilt Brain Institute, Vanderbilt University, Nashville, TN 37240., Skiniotis G; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305.; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305., Khavari PA; Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA 94305.; Program in Cancer Biology, Stanford University, Stanford, CA 94305.; Veterans Affairs Palo Alto Healthcare System, Palo Alto, CA 94304.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2025 Nov 25; Vol. 122 (47), pp. e2508436122. Date of Electronic Publication: 2025 Nov 18.
Publication Type: Journal Article
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1091-6490
DOI:10.1073/pnas.2508436122