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Monocyte inflammation and resilience to Alzheimer's disease: novel genetic risk genes identified by transcriptome-wide association study.

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Title: Monocyte inflammation and resilience to Alzheimer's disease: novel genetic risk genes identified by transcriptome-wide association study.
Authors: Mustafa Y; Cleveland Institute for Computational Biology, Case Western Reserve University, Cleveland, OH, USA. yim2@case.edu.; Systems Biology and Bioinformatics, Department of Nutrition, Case Western Reserve University School of Medicine, Cleveland, OH, USA. yim2@case.edu., Main LR; Cleveland Institute for Computational Biology, Case Western Reserve University, Cleveland, OH, USA., Mews M; Cleveland Institute for Computational Biology, Case Western Reserve University, Cleveland, OH, USA.; Systems Biology and Bioinformatics, Department of Nutrition, Case Western Reserve University School of Medicine, Cleveland, OH, USA., Janve VA; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University Medical Center, Nashville, TN, USA., Hohman TJ; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University Medical Center, Nashville, TN, USA.; Vanderbilt Genetics Institute and Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Haines JL; Cleveland Institute for Computational Biology, Case Western Reserve University, Cleveland, OH, USA., Song YE; Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, USA., Griswold AJ; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA and The Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami Miller School of Medicine, Miami, FL, USA., Pericak-Vance MA; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA and The Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami Miller School of Medicine, Miami, FL, USA., Scott WK; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA and The Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami Miller School of Medicine, Miami, FL, USA., Naj AC; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.; Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Below JE; Vanderbilt Genetics Institute and Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Dumitrescu L; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University Medical Center, Nashville, TN, USA.; Vanderbilt Genetics Institute and Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Bush WS; Cleveland Institute for Computational Biology, Case Western Reserve University, Cleveland, OH, USA. wsb36@case.edu.
Source: Translational psychiatry [Transl Psychiatry] 2025 Nov 18; Vol. 15 (1), pp. 481. Date of Electronic Publication: 2025 Nov 18.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101562664 Publication Model: Electronic Cited Medium: Internet ISSN: 2158-3188 (Electronic) Linking ISSN: 21583188 NLM ISO Abbreviation: Transl Psychiatry Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Mustafa+Y%22">Mustafa Y</searchLink>; Cleveland Institute for Computational Biology, Case Western Reserve University, Cleveland, OH, USA. yim2@case.edu.; Systems Biology and Bioinformatics, Department of Nutrition, Case Western Reserve University School of Medicine, Cleveland, OH, USA. yim2@case.edu.<br /><searchLink fieldCode="AU" term="%22Main+LR%22">Main LR</searchLink>; Cleveland Institute for Computational Biology, Case Western Reserve University, Cleveland, OH, USA.<br /><searchLink fieldCode="AU" term="%22Mews+M%22">Mews M</searchLink>; Cleveland Institute for Computational Biology, Case Western Reserve University, Cleveland, OH, USA.; Systems Biology and Bioinformatics, Department of Nutrition, Case Western Reserve University School of Medicine, Cleveland, OH, USA.<br /><searchLink fieldCode="AU" term="%22Janve+VA%22">Janve VA</searchLink>; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Hohman+TJ%22">Hohman TJ</searchLink>; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University Medical Center, Nashville, TN, USA.; Vanderbilt Genetics Institute and Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Haines+JL%22">Haines JL</searchLink>; Cleveland Institute for Computational Biology, Case Western Reserve University, Cleveland, OH, USA.<br /><searchLink fieldCode="AU" term="%22Song+YE%22">Song YE</searchLink>; Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, USA.<br /><searchLink fieldCode="AU" term="%22Griswold+AJ%22">Griswold AJ</searchLink>; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA and The Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami Miller School of Medicine, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Pericak-Vance+MA%22">Pericak-Vance MA</searchLink>; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA and The Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami Miller School of Medicine, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Scott+WK%22">Scott WK</searchLink>; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA and The Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami Miller School of Medicine, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Naj+AC%22">Naj AC</searchLink>; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.; Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Below+JE%22">Below JE</searchLink>; Vanderbilt Genetics Institute and Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Dumitrescu+L%22">Dumitrescu L</searchLink>; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University Medical Center, Nashville, TN, USA.; Vanderbilt Genetics Institute and Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Bush+WS%22">Bush WS</searchLink>; Cleveland Institute for Computational Biology, Case Western Reserve University, Cleveland, OH, USA. wsb36@case.edu.
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  Data: <searchLink fieldCode="JN" term="%22101562664%22">Translational psychiatry</searchLink> [Transl Psychiatry] 2025 Nov 18; Vol. 15 (1), pp. 481. <i>Date of Electronic Publication: </i>2025 Nov 18.
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