mRNA delivery of circumsporozoite protein epitope-based malaria vaccines induces protection in a mouse model.
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| Title: | mRNA delivery of circumsporozoite protein epitope-based malaria vaccines induces protection in a mouse model. |
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| Authors: | Wu NR; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Beutler N; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA., Hu X; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; Moderna Inc., Cambridge, MA, USA., Skog PD; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA., Liguori A; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA., Flores-Garcia Y; Johns Hopkins Malaria Research Institute, Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA., Maiorino L; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.; Howard Hughes Medical Institute, Chevy Chase, MD, USA., Terada S; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA., Lu D; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA., Lai YC; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; Division of Infectious Diseases, Department of Medicine, University of California, San Diego, La Jolla, CA, USA., Ndihokubwayo J; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; Division of Infectious Diseases, Department of Medicine, University of California, San Diego, La Jolla, CA, USA., Schiffner T; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA., Cottrell CA; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA., Eskandarzadeh S; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA., Alavi N; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA., Kubitz M; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA., Phelps N; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA., Tingle R; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA., Hodges S; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA., Youhanna JE; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA., Amirzehni S; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA., Irvine DJ; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.; Howard Hughes Medical Institute, Chevy Chase, MD, USA.; The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA., Himansu S; Moderna Inc., Cambridge, MA, USA., Zavala F; Johns Hopkins Malaria Research Institute, Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA., Rogers TF; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA. trogers@scripps.edu.; Division of Infectious Diseases, Department of Medicine, University of California, San Diego, La Jolla, CA, USA. trogers@scripps.edu., Burton DR; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA. burton@scripps.edu.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA. burton@scripps.edu.; The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA. burton@scripps.edu., Schief WR; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA. schief@scripps.edu.; Moderna Inc., Cambridge, MA, USA. schief@scripps.edu.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA. schief@scripps.edu. |
| Source: | NPJ vaccines [NPJ Vaccines] 2025 Nov 18; Vol. 10 (1), pp. 238. Date of Electronic Publication: 2025 Nov 18. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer Nature in partnership with the Sealy Center for Vaccine Development Country of Publication: England NLM ID: 101699863 Publication Model: Electronic Cited Medium: Internet ISSN: 2059-0105 (Electronic) Linking ISSN: 20590105 NLM ISO Abbreviation: NPJ Vaccines Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41253879 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: mRNA delivery of circumsporozoite protein epitope-based malaria vaccines induces protection in a mouse model. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Wu+NR%22">Wu NR</searchLink>; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Beutler+N%22">Beutler N</searchLink>; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Hu+X%22">Hu X</searchLink>; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; Moderna Inc., Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Skog+PD%22">Skog PD</searchLink>; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Liguori+A%22">Liguori A</searchLink>; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Flores-Garcia+Y%22">Flores-Garcia Y</searchLink>; Johns Hopkins Malaria Research Institute, Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Maiorino+L%22">Maiorino L</searchLink>; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.; Howard Hughes Medical Institute, Chevy Chase, MD, USA.<br /><searchLink fieldCode="AU" term="%22Terada+S%22">Terada S</searchLink>; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Lu+D%22">Lu D</searchLink>; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Lai+YC%22">Lai YC</searchLink>; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; Division of Infectious Diseases, Department of Medicine, University of California, San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Ndihokubwayo+J%22">Ndihokubwayo J</searchLink>; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; Division of Infectious Diseases, Department of Medicine, University of California, San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Schiffner+T%22">Schiffner T</searchLink>; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Cottrell+CA%22">Cottrell CA</searchLink>; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Eskandarzadeh+S%22">Eskandarzadeh S</searchLink>; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Alavi+N%22">Alavi N</searchLink>; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Kubitz+M%22">Kubitz M</searchLink>; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Phelps+N%22">Phelps N</searchLink>; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Tingle+R%22">Tingle R</searchLink>; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Hodges+S%22">Hodges S</searchLink>; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Youhanna+JE%22">Youhanna JE</searchLink>; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Amirzehni+S%22">Amirzehni S</searchLink>; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Irvine+DJ%22">Irvine DJ</searchLink>; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.; Howard Hughes Medical Institute, Chevy Chase, MD, USA.; The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Himansu+S%22">Himansu S</searchLink>; Moderna Inc., Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Zavala+F%22">Zavala F</searchLink>; Johns Hopkins Malaria Research Institute, Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Rogers+TF%22">Rogers TF</searchLink>; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA. trogers@scripps.edu.; Division of Infectious Diseases, Department of Medicine, University of California, San Diego, La Jolla, CA, USA. trogers@scripps.edu.<br /><searchLink fieldCode="AU" term="%22Burton+DR%22">Burton DR</searchLink>; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA. burton@scripps.edu.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA. burton@scripps.edu.; The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA. burton@scripps.edu.<br /><searchLink fieldCode="AU" term="%22Schief+WR%22">Schief WR</searchLink>; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USA. schief@scripps.edu.; Moderna Inc., Cambridge, MA, USA. schief@scripps.edu.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA, USA. schief@scripps.edu. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101699863%22">NPJ vaccines</searchLink> [NPJ Vaccines] 2025 Nov 18; Vol. 10 (1), pp. 238. <i>Date of Electronic Publication: </i>2025 Nov 18. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Nature+in+partnership+with+the+Sealy+Center+for+Vaccine+Development%22">Springer Nature in partnership with the Sealy Center for Vaccine Development </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101699863 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2059-0105 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220590105%22">20590105 </searchLink><i>NLM ISO Abbreviation: </i>NPJ Vaccines <i>Subsets: </i>PubMed not MEDLINE |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/s41541-025-01296-6 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 238 Titles: – TitleFull: mRNA delivery of circumsporozoite protein epitope-based malaria vaccines induces protection in a mouse model. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Wu NR – PersonEntity: Name: NameFull: Beutler N – PersonEntity: Name: NameFull: Hu X – PersonEntity: Name: NameFull: Skog PD – PersonEntity: Name: NameFull: Liguori A – PersonEntity: Name: NameFull: Flores-Garcia Y – PersonEntity: Name: NameFull: Maiorino L – PersonEntity: Name: NameFull: Terada S – PersonEntity: Name: NameFull: Lu D – PersonEntity: Name: NameFull: Lai YC – PersonEntity: Name: NameFull: Ndihokubwayo J – PersonEntity: Name: NameFull: Schiffner T – PersonEntity: Name: NameFull: Cottrell CA – PersonEntity: Name: NameFull: Eskandarzadeh S – PersonEntity: Name: NameFull: Alavi N – PersonEntity: Name: NameFull: Kubitz M – PersonEntity: Name: NameFull: Phelps N – PersonEntity: Name: NameFull: Tingle R – PersonEntity: Name: NameFull: Hodges S – PersonEntity: Name: NameFull: Youhanna JE – PersonEntity: Name: NameFull: Amirzehni S – PersonEntity: Name: NameFull: Irvine DJ – PersonEntity: Name: NameFull: Himansu S – PersonEntity: Name: NameFull: Zavala F – PersonEntity: Name: NameFull: Rogers TF – PersonEntity: Name: NameFull: Burton DR – PersonEntity: Name: NameFull: Schief WR IsPartOfRelationships: – BibEntity: Dates: – D: 18 M: 11 Text: 2025 Nov 18 Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 2059-0105 Numbering: – Type: volume Value: 10 – Type: issue Value: 1 Titles: – TitleFull: NPJ vaccines Type: main |
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