Leveraging in vitro Tumor Cell Killing and Cytokine Release to Predict Cytokine Release Syndrome Associated with CD3 T-cell Bispecifics in Oncology: a Retrospective Analysis.
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| Title: | Leveraging in vitro Tumor Cell Killing and Cytokine Release to Predict Cytokine Release Syndrome Associated with CD3 T-cell Bispecifics in Oncology: a Retrospective Analysis. |
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| Authors: | Lefèvre A; Roche Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., Grenzacherstrasse 124, Basel, 4070, Switzerland. apolline.lefevre@roche.com.; Pharmacometrics & Systems Pharmacology, Department of Pharmaceutical Science. School of Pharmacy and Nutrition, University of Navarra, Pamplona, 31009, Spain. apolline.lefevre@roche.com., Parra-Guillen ZP; Pharmacometrics & Systems Pharmacology, Department of Pharmaceutical Science. School of Pharmacy and Nutrition, University of Navarra, Pamplona, 31009, Spain.; Navarra Institute for Health Research (IdiSNA), Pamplona, 31009, Spain., Trocóniz IF; Pharmacometrics & Systems Pharmacology, Department of Pharmaceutical Science. School of Pharmacy and Nutrition, University of Navarra, Pamplona, 31009, Spain.; Navarra Institute for Health Research (IdiSNA), Pamplona, 31009, Spain.; Institute of Data Science and Artificial Intelligence, DATAI, University of Navarra, Pamplona, 31009, Spain., Boetsch C; Roche Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., Grenzacherstrasse 124, Basel, 4070, Switzerland., Frances N; Roche Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., Grenzacherstrasse 124, Basel, 4070, Switzerland. |
| Source: | The AAPS journal [AAPS J] 2025 Nov 18; Vol. 28 (1), pp. 20. Date of Electronic Publication: 2025 Nov 18. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Association of Pharmaceutical Scientists Country of Publication: United States NLM ID: 101223209 Publication Model: Electronic Cited Medium: Internet ISSN: 1550-7416 (Electronic) Linking ISSN: 15507416 NLM ISO Abbreviation: AAPS J Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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