Persistent interferon signaling and clonal expansion mark early events in DNA methylation damage-induced liver cancer.

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Title: Persistent interferon signaling and clonal expansion mark early events in DNA methylation damage-induced liver cancer.
Authors: Pribyl LJ; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., Kay JE; Silent Spring Institute, Newton, MA, 02460, USA., Corrigan JJ; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., Volk LB; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., Norales M; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., Owiti NA; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., Kowal EA; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., Kohale IN; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., Nazari IS; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., Swanson MR; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., Moise AC; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., Ma D; David H. Koch Institute for Integrative Cancer Research, Bioinformatics and Computing Facility of Swanson Biotechnology Center, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., Levine SS; BioMicro Center, Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., Michelsen E; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., Croy RG; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., Ragan T; TissueVision, Newton, MA, 02458, USA., Torous DK; Litron Laboratories, Rochester, NY, 14623, USA., Avlasevich SL; Litron Laboratories, Rochester, NY, 14623, USA., Dertinger SD; Litron Laboratories, Rochester, NY, 14623, USA., Carrasco SE; Laboratory of Comparative Pathology, Weill Cornell Medicine, Memorial Sloan Kettering Cancer Center and Rockefeller University, New York, NY, 10065, USA., Samson LD; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., Essigmann JM; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., White FM; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., Engelward BP; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Oct 03. Date of Electronic Publication: 2025 Oct 03.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Persistent interferon signaling and clonal expansion mark early events in DNA methylation damage-induced liver cancer.
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  Data: <searchLink fieldCode="AU" term="%22Pribyl+LJ%22">Pribyl LJ</searchLink>; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.<br /><searchLink fieldCode="AU" term="%22Kay+JE%22">Kay JE</searchLink>; Silent Spring Institute, Newton, MA, 02460, USA.<br /><searchLink fieldCode="AU" term="%22Corrigan+JJ%22">Corrigan JJ</searchLink>; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.<br /><searchLink fieldCode="AU" term="%22Volk+LB%22">Volk LB</searchLink>; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.<br /><searchLink fieldCode="AU" term="%22Norales+M%22">Norales M</searchLink>; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.<br /><searchLink fieldCode="AU" term="%22Owiti+NA%22">Owiti NA</searchLink>; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.<br /><searchLink fieldCode="AU" term="%22Kowal+EA%22">Kowal EA</searchLink>; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.<br /><searchLink fieldCode="AU" term="%22Kohale+IN%22">Kohale IN</searchLink>; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.<br /><searchLink fieldCode="AU" term="%22Nazari+IS%22">Nazari IS</searchLink>; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.<br /><searchLink fieldCode="AU" term="%22Swanson+MR%22">Swanson MR</searchLink>; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.<br /><searchLink fieldCode="AU" term="%22Moise+AC%22">Moise AC</searchLink>; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.<br /><searchLink fieldCode="AU" term="%22Ma+D%22">Ma D</searchLink>; David H. Koch Institute for Integrative Cancer Research, Bioinformatics and Computing Facility of Swanson Biotechnology Center, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.<br /><searchLink fieldCode="AU" term="%22Levine+SS%22">Levine SS</searchLink>; BioMicro Center, Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.<br /><searchLink fieldCode="AU" term="%22Michelsen+E%22">Michelsen E</searchLink>; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.<br /><searchLink fieldCode="AU" term="%22Croy+RG%22">Croy RG</searchLink>; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.<br /><searchLink fieldCode="AU" term="%22Ragan+T%22">Ragan T</searchLink>; TissueVision, Newton, MA, 02458, USA.<br /><searchLink fieldCode="AU" term="%22Torous+DK%22">Torous DK</searchLink>; Litron Laboratories, Rochester, NY, 14623, USA.<br /><searchLink fieldCode="AU" term="%22Avlasevich+SL%22">Avlasevich SL</searchLink>; Litron Laboratories, Rochester, NY, 14623, USA.<br /><searchLink fieldCode="AU" term="%22Dertinger+SD%22">Dertinger SD</searchLink>; Litron Laboratories, Rochester, NY, 14623, USA.<br /><searchLink fieldCode="AU" term="%22Carrasco+SE%22">Carrasco SE</searchLink>; Laboratory of Comparative Pathology, Weill Cornell Medicine, Memorial Sloan Kettering Cancer Center and Rockefeller University, New York, NY, 10065, USA.<br /><searchLink fieldCode="AU" term="%22Samson+LD%22">Samson LD</searchLink>; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.<br /><searchLink fieldCode="AU" term="%22Essigmann+JM%22">Essigmann JM</searchLink>; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.<br /><searchLink fieldCode="AU" term="%22White+FM%22">White FM</searchLink>; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.<br /><searchLink fieldCode="AU" term="%22Engelward+BP%22">Engelward BP</searchLink>; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
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