View in EDS

Random forest model improves annotation and discovery of variants of uncertain significance in Alzheimer's and other neurological disorders.

Saved in:
Bibliographic Details
Title: Random forest model improves annotation and discovery of variants of uncertain significance in Alzheimer's and other neurological disorders.
Authors: Jonson C; Center for Alzheimer's and Related Dementias, Bethesda, MD, USA 20892.; DataTecnica LLC, Washington, DC, USA 20037.; Memory and Aging Center, Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco, CA, USA., Makarious MB; Center for Alzheimer's and Related Dementias, Bethesda, MD, USA 20892.; DataTecnica LLC, Washington, DC, USA 20037., Koretsky MJ; Center for Alzheimer's and Related Dementias, Bethesda, MD, USA 20892.; DataTecnica LLC, Washington, DC, USA 20037., Vitale D; Center for Alzheimer's and Related Dementias, Bethesda, MD, USA 20892.; DataTecnica LLC, Washington, DC, USA 20037., Rabkina L; Memory and Aging Center, Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco, CA, USA., Lago AL; Memory and Aging Center, Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco, CA, USA., Eslami-Amirabadi M; Memory and Aging Center, Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco, CA, USA.; University of Washington, School of Medicine, Memory and Brain Wellness Center at Harborview, Seattle, WA, 98104., Ramos EM; Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA., Narayan P; Center for Alzheimer's and Related Dementias, Bethesda, MD, USA 20892., Yokoyama JS; Memory and Aging Center, Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco, CA, USA.; Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA., Singleton AB; Center for Alzheimer's and Related Dementias, Bethesda, MD, USA 20892., Blauwendraat C; Coalition for Aligning Science, Chevy Chase, MD, USA; Global Parkinson's Genetics Program, Chevy Chase, MD, USA; Aligning Science Across Parkinson's (ASAP), Chevy Chase, MD, USA., Cookson MR; Center for Alzheimer's and Related Dementias, Bethesda, MD, USA 20892.; Laboratory of Neurogenetics, NIA, NIH, Bethesda, MD, USA 20892., Nalls MA; Center for Alzheimer's and Related Dementias, Bethesda, MD, USA 20892.; DataTecnica LLC, Washington, DC, USA 20037.; Laboratory of Neurogenetics, NIA, NIH, Bethesda, MD, USA 20892., Leonard HL; Center for Alzheimer's and Related Dementias, Bethesda, MD, USA 20892.; DataTecnica LLC, Washington, DC, USA 20037.; Laboratory of Neurogenetics, NIA, NIH, Bethesda, MD, USA 20892.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Oct 02. Date of Electronic Publication: 2025 Oct 02.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 41256702
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Random forest model improves annotation and discovery of variants of uncertain significance in Alzheimer's and other neurological disorders.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Jonson+C%22">Jonson C</searchLink>; Center for Alzheimer's and Related Dementias, Bethesda, MD, USA 20892.; DataTecnica LLC, Washington, DC, USA 20037.; Memory and Aging Center, Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Makarious+MB%22">Makarious MB</searchLink>; Center for Alzheimer's and Related Dementias, Bethesda, MD, USA 20892.; DataTecnica LLC, Washington, DC, USA 20037.<br /><searchLink fieldCode="AU" term="%22Koretsky+MJ%22">Koretsky MJ</searchLink>; Center for Alzheimer's and Related Dementias, Bethesda, MD, USA 20892.; DataTecnica LLC, Washington, DC, USA 20037.<br /><searchLink fieldCode="AU" term="%22Vitale+D%22">Vitale D</searchLink>; Center for Alzheimer's and Related Dementias, Bethesda, MD, USA 20892.; DataTecnica LLC, Washington, DC, USA 20037.<br /><searchLink fieldCode="AU" term="%22Rabkina+L%22">Rabkina L</searchLink>; Memory and Aging Center, Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Lago+AL%22">Lago AL</searchLink>; Memory and Aging Center, Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Eslami-Amirabadi+M%22">Eslami-Amirabadi M</searchLink>; Memory and Aging Center, Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco, CA, USA.; University of Washington, School of Medicine, Memory and Brain Wellness Center at Harborview, Seattle, WA, 98104.<br /><searchLink fieldCode="AU" term="%22Ramos+EM%22">Ramos EM</searchLink>; Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Narayan+P%22">Narayan P</searchLink>; Center for Alzheimer's and Related Dementias, Bethesda, MD, USA 20892.<br /><searchLink fieldCode="AU" term="%22Yokoyama+JS%22">Yokoyama JS</searchLink>; Memory and Aging Center, Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco, CA, USA.; Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Singleton+AB%22">Singleton AB</searchLink>; Center for Alzheimer's and Related Dementias, Bethesda, MD, USA 20892.<br /><searchLink fieldCode="AU" term="%22Blauwendraat+C%22">Blauwendraat C</searchLink>; Coalition for Aligning Science, Chevy Chase, MD, USA; Global Parkinson's Genetics Program, Chevy Chase, MD, USA; Aligning Science Across Parkinson's (ASAP), Chevy Chase, MD, USA.<br /><searchLink fieldCode="AU" term="%22Cookson+MR%22">Cookson MR</searchLink>; Center for Alzheimer's and Related Dementias, Bethesda, MD, USA 20892.; Laboratory of Neurogenetics, NIA, NIH, Bethesda, MD, USA 20892.<br /><searchLink fieldCode="AU" term="%22Nalls+MA%22">Nalls MA</searchLink>; Center for Alzheimer's and Related Dementias, Bethesda, MD, USA 20892.; DataTecnica LLC, Washington, DC, USA 20037.; Laboratory of Neurogenetics, NIA, NIH, Bethesda, MD, USA 20892.<br /><searchLink fieldCode="AU" term="%22Leonard+HL%22">Leonard HL</searchLink>; Center for Alzheimer's and Related Dementias, Bethesda, MD, USA 20892.; DataTecnica LLC, Washington, DC, USA 20037.; Laboratory of Neurogenetics, NIA, NIH, Bethesda, MD, USA 20892.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101680187%22">BioRxiv : the preprint server for biology</searchLink> [bioRxiv] 2025 Oct 02. <i>Date of Electronic Publication: </i>2025 Oct 02.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Preprint
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Country of Publication: </i>United States <i>NLM ID: </i>101680187 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2692-8205 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226928205%22">26928205 </searchLink><i>NLM ISO Abbreviation: </i>bioRxiv <i>Subsets: </i>PubMed not MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41256702
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1101/2025.10.02.680068
    Languages:
      – Code: eng
        Text: English
    Titles:
      – TitleFull: Random forest model improves annotation and discovery of variants of uncertain significance in Alzheimer's and other neurological disorders.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Jonson C
      – PersonEntity:
          Name:
            NameFull: Makarious MB
      – PersonEntity:
          Name:
            NameFull: Koretsky MJ
      – PersonEntity:
          Name:
            NameFull: Vitale D
      – PersonEntity:
          Name:
            NameFull: Rabkina L
      – PersonEntity:
          Name:
            NameFull: Lago AL
      – PersonEntity:
          Name:
            NameFull: Eslami-Amirabadi M
      – PersonEntity:
          Name:
            NameFull: Ramos EM
      – PersonEntity:
          Name:
            NameFull: Narayan P
      – PersonEntity:
          Name:
            NameFull: Yokoyama JS
      – PersonEntity:
          Name:
            NameFull: Singleton AB
      – PersonEntity:
          Name:
            NameFull: Blauwendraat C
      – PersonEntity:
          Name:
            NameFull: Cookson MR
      – PersonEntity:
          Name:
            NameFull: Nalls MA
      – PersonEntity:
          Name:
            NameFull: Leonard HL
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 02
              M: 10
              Text: 2025 Oct 02
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-electronic
              Value: 2692-8205
          Titles:
            – TitleFull: BioRxiv : the preprint server for biology
              Type: main
ResultId 1