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Benchtop NMR urine metabolomics for diagnosing pulmonary tuberculosis.

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Title: Benchtop NMR urine metabolomics for diagnosing pulmonary tuberculosis.
Authors: Comella-Del-Barrio P; Institut d'Investigació Germans Trias i Pujol, 08916, Badalona, Barcelona, Spain.; Paediatric Infectious Diseases Unit, Gregorio Marañón Mother and Child Hospital, 28009, Madrid, Spain.; Tropical Medicine and International Health Unit, Infectious Diseases Department, Vall Hebron Research Institute (VHIR), 08035, Barcelona, Spain.; CIBER de Enfermedades Infecciosas (CIBERINFEC), Instituto de Salud Carlos III, 28029, Madrid, Spain., Rodríguez I; Department of Chemistry in Pharmaceutical Sciences, Pharmacy School, Universidad Complutense de Madrid, 28040, Madrid, Spain.; NMR and Imaging in Biomedicine Group, Instituto Pluridisciplinar, Universidad Complutense de Madrid, 28040, Madrid, Spain.; CIBER de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, 28029, Madrid, Spain., Bimba JS; Zankli Research Centre and Department of Community Medicine, Bingham University, Karu, 961105, Nigeria., Osazuwa O; Zankli Research Centre and Department of Community Medicine, Bingham University, Karu, 961105, Nigeria., Alaran R; Centre for Drugs and Diagnostics, Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, L3 5QA, UK., Alonso-Moreno P; Department of Chemistry in Pharmaceutical Sciences, Pharmacy School, Universidad Complutense de Madrid, 28040, Madrid, Spain.; NMR and Imaging in Biomedicine Group, Instituto Pluridisciplinar, Universidad Complutense de Madrid, 28040, Madrid, Spain., Blasco-Iturri Z; CIBER de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, 28029, Madrid, Spain.; CIC biomaGUNE, Basque Research and Technology Alliance (BRTA), 20014, Donostia San Sebastián, Spain.; German Center for Lung Research (DZL), Institute for Lung Health (ILH), Justus-Liebig University, Universities of Giessen and Marburg Lung Center (UGMLC), Giessen, Germany.; Cardio-Pulmonary Institute (CPI), Justus-Liebig University, Giessen, Germany., Miguel-Coello AB; CIBER de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, 28029, Madrid, Spain.; CIC biomaGUNE, Basque Research and Technology Alliance (BRTA), 20014, Donostia San Sebastián, Spain., Cuevas LE; Centre for Drugs and Diagnostics, Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, L3 5QA, UK., Ruiz-Cabello J; Department of Chemistry in Pharmaceutical Sciences, Pharmacy School, Universidad Complutense de Madrid, 28040, Madrid, Spain.; CIBER de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, 28029, Madrid, Spain.; CIC biomaGUNE, Basque Research and Technology Alliance (BRTA), 20014, Donostia San Sebastián, Spain.; Ikerbasque, Basque Foundation for Science, 48009, Bilbao, Spain., Izquierdo-Garcia JL; Department of Chemistry in Pharmaceutical Sciences, Pharmacy School, Universidad Complutense de Madrid, 28040, Madrid, Spain. jlizquierdo@ucm.es.; NMR and Imaging in Biomedicine Group, Instituto Pluridisciplinar, Universidad Complutense de Madrid, 28040, Madrid, Spain. jlizquierdo@ucm.es.; CIBER de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, 28029, Madrid, Spain. jlizquierdo@ucm.es., Domínguez J; Institut d'Investigació Germans Trias i Pujol, 08916, Badalona, Barcelona, Spain. jadominguez@igtp.cat.; CIBER de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, 28029, Madrid, Spain. jadominguez@igtp.cat.; Department of Genetics and Microbiology, Biosciences Faculty, Universitat Autònoma de Barcelona, Bellaterra, Barcelona, Spain. jadominguez@igtp.cat.
Source: Scientific reports [Sci Rep] 2025 Nov 19; Vol. 15 (1), pp. 40881. Date of Electronic Publication: 2025 Nov 19.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
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  Data: Benchtop NMR urine metabolomics for diagnosing pulmonary tuberculosis.
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  Data: <searchLink fieldCode="AU" term="%22Comella-Del-Barrio+P%22">Comella-Del-Barrio P</searchLink>; Institut d'Investigació Germans Trias i Pujol, 08916, Badalona, Barcelona, Spain.; Paediatric Infectious Diseases Unit, Gregorio Marañón Mother and Child Hospital, 28009, Madrid, Spain.; Tropical Medicine and International Health Unit, Infectious Diseases Department, Vall Hebron Research Institute (VHIR), 08035, Barcelona, Spain.; CIBER de Enfermedades Infecciosas (CIBERINFEC), Instituto de Salud Carlos III, 28029, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Rodríguez+I%22">Rodríguez I</searchLink>; Department of Chemistry in Pharmaceutical Sciences, Pharmacy School, Universidad Complutense de Madrid, 28040, Madrid, Spain.; NMR and Imaging in Biomedicine Group, Instituto Pluridisciplinar, Universidad Complutense de Madrid, 28040, Madrid, Spain.; CIBER de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, 28029, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Bimba+JS%22">Bimba JS</searchLink>; Zankli Research Centre and Department of Community Medicine, Bingham University, Karu, 961105, Nigeria.<br /><searchLink fieldCode="AU" term="%22Osazuwa+O%22">Osazuwa O</searchLink>; Zankli Research Centre and Department of Community Medicine, Bingham University, Karu, 961105, Nigeria.<br /><searchLink fieldCode="AU" term="%22Alaran+R%22">Alaran R</searchLink>; Centre for Drugs and Diagnostics, Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, L3 5QA, UK.<br /><searchLink fieldCode="AU" term="%22Alonso-Moreno+P%22">Alonso-Moreno P</searchLink>; Department of Chemistry in Pharmaceutical Sciences, Pharmacy School, Universidad Complutense de Madrid, 28040, Madrid, Spain.; NMR and Imaging in Biomedicine Group, Instituto Pluridisciplinar, Universidad Complutense de Madrid, 28040, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Blasco-Iturri+Z%22">Blasco-Iturri Z</searchLink>; CIBER de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, 28029, Madrid, Spain.; CIC biomaGUNE, Basque Research and Technology Alliance (BRTA), 20014, Donostia San Sebastián, Spain.; German Center for Lung Research (DZL), Institute for Lung Health (ILH), Justus-Liebig University, Universities of Giessen and Marburg Lung Center (UGMLC), Giessen, Germany.; Cardio-Pulmonary Institute (CPI), Justus-Liebig University, Giessen, Germany.<br /><searchLink fieldCode="AU" term="%22Miguel-Coello+AB%22">Miguel-Coello AB</searchLink>; CIBER de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, 28029, Madrid, Spain.; CIC biomaGUNE, Basque Research and Technology Alliance (BRTA), 20014, Donostia San Sebastián, Spain.<br /><searchLink fieldCode="AU" term="%22Cuevas+LE%22">Cuevas LE</searchLink>; Centre for Drugs and Diagnostics, Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, L3 5QA, UK.<br /><searchLink fieldCode="AU" term="%22Ruiz-Cabello+J%22">Ruiz-Cabello J</searchLink>; Department of Chemistry in Pharmaceutical Sciences, Pharmacy School, Universidad Complutense de Madrid, 28040, Madrid, Spain.; CIBER de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, 28029, Madrid, Spain.; CIC biomaGUNE, Basque Research and Technology Alliance (BRTA), 20014, Donostia San Sebastián, Spain.; Ikerbasque, Basque Foundation for Science, 48009, Bilbao, Spain.<br /><searchLink fieldCode="AU" term="%22Izquierdo-Garcia+JL%22">Izquierdo-Garcia JL</searchLink>; Department of Chemistry in Pharmaceutical Sciences, Pharmacy School, Universidad Complutense de Madrid, 28040, Madrid, Spain. jlizquierdo@ucm.es.; NMR and Imaging in Biomedicine Group, Instituto Pluridisciplinar, Universidad Complutense de Madrid, 28040, Madrid, Spain. jlizquierdo@ucm.es.; CIBER de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, 28029, Madrid, Spain. jlizquierdo@ucm.es.<br /><searchLink fieldCode="AU" term="%22Domínguez+J%22">Domínguez J</searchLink>; Institut d'Investigació Germans Trias i Pujol, 08916, Badalona, Barcelona, Spain. jadominguez@igtp.cat.; CIBER de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, 28029, Madrid, Spain. jadominguez@igtp.cat.; Department of Genetics and Microbiology, Biosciences Faculty, Universitat Autònoma de Barcelona, Bellaterra, Barcelona, Spain. jadominguez@igtp.cat.
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