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Metabolic Rigidity as a Mechanical Barrier to Malaria: Flickering Loss in PKLR-Deficient Erythrocytes.

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Title: Metabolic Rigidity as a Mechanical Barrier to Malaria: Flickering Loss in PKLR-Deficient Erythrocytes.
Authors: Hernando-Ospina N; Department of Physical Chemistry, Complutense University of Madrid, Madrid, Spain., Calero M; Department of Physical Chemistry, Complutense University of Madrid, Madrid, Spain.; Translational Biophysics (imas12), Hospital Universitario 12 De Octubre, Madrid, Spain.; Faculty of Health Sciences - HM Hospitals, University Camilo José Cela, Madrid, Spain.; HM Hospitals Health Research Institute, Madrid, Spain., Solís G; Department of Physical Chemistry, Complutense University of Madrid, Madrid, Spain.; Translational Biophysics (imas12), Hospital Universitario 12 De Octubre, Madrid, Spain., Azcárate IG; Faculty of Health Sciences, Rey Juan Carlos University, Madrid, Spain.; Translational Malaria Unit, 12 De Octubre Health Research Institute (imas12), Madrid, Spain., Herráez-Aguilar D; Translational Biophysics (imas12), Hospital Universitario 12 De Octubre, Madrid, Spain.; Faculty of Experimental Sciences, University Francisco De Vitoria, Madrid, Spain., Caselli N; Department of Physical Chemistry, Complutense University of Madrid, Madrid, Spain.; Translational Biophysics (imas12), Hospital Universitario 12 De Octubre, Madrid, Spain., Moleiro LH; Department of Physical Chemistry, Complutense University of Madrid, Madrid, Spain.; Translational Biophysics (imas12), Hospital Universitario 12 De Octubre, Madrid, Spain., Segovia JC; Cell Technology Division, Biomedical Innovation Unit. Centro de Investigaciones Energéticas Medioambientales Y Tecnológicas and Centro De Investigación Biomédica En Red De Enfermedades Raras (CIEMAT/CIBERER), Madrid, Spain.; Advanced Therapies Unit, Instituto De Investigación Sanitaria Fundación Jiménez Díaz (IIS-FJD, UAM), Madrid, Spain., Bautista JM; Translational Malaria Unit, 12 De Octubre Health Research Institute (imas12), Madrid, Spain.; Department of Biochemistry and Molecular Biology, Universidad Complutense De Madrid, Madrid, Spain., Monroy F; Department of Physical Chemistry, Complutense University of Madrid, Madrid, Spain.; Translational Biophysics (imas12), Hospital Universitario 12 De Octubre, Madrid, Spain.
Source: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2025 Nov 30; Vol. 39 (22), pp. e71234.
Publication Type: Journal Article
Journal Info: Publisher: Federation of American Societies for Experimental Biology Country of Publication: United States NLM ID: 8804484 Publication Model: Print Cited Medium: Internet ISSN: 1530-6860 (Electronic) Linking ISSN: 08926638 NLM ISO Abbreviation: FASEB J Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Hernando-Ospina+N%22">Hernando-Ospina N</searchLink>; Department of Physical Chemistry, Complutense University of Madrid, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Calero+M%22">Calero M</searchLink>; Department of Physical Chemistry, Complutense University of Madrid, Madrid, Spain.; Translational Biophysics (imas12), Hospital Universitario 12 De Octubre, Madrid, Spain.; Faculty of Health Sciences - HM Hospitals, University Camilo José Cela, Madrid, Spain.; HM Hospitals Health Research Institute, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Solís+G%22">Solís G</searchLink>; Department of Physical Chemistry, Complutense University of Madrid, Madrid, Spain.; Translational Biophysics (imas12), Hospital Universitario 12 De Octubre, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Azcárate+IG%22">Azcárate IG</searchLink>; Faculty of Health Sciences, Rey Juan Carlos University, Madrid, Spain.; Translational Malaria Unit, 12 De Octubre Health Research Institute (imas12), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Herráez-Aguilar+D%22">Herráez-Aguilar D</searchLink>; Translational Biophysics (imas12), Hospital Universitario 12 De Octubre, Madrid, Spain.; Faculty of Experimental Sciences, University Francisco De Vitoria, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Caselli+N%22">Caselli N</searchLink>; Department of Physical Chemistry, Complutense University of Madrid, Madrid, Spain.; Translational Biophysics (imas12), Hospital Universitario 12 De Octubre, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Moleiro+LH%22">Moleiro LH</searchLink>; Department of Physical Chemistry, Complutense University of Madrid, Madrid, Spain.; Translational Biophysics (imas12), Hospital Universitario 12 De Octubre, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Segovia+JC%22">Segovia JC</searchLink>; Cell Technology Division, Biomedical Innovation Unit. Centro de Investigaciones Energéticas Medioambientales Y Tecnológicas and Centro De Investigación Biomédica En Red De Enfermedades Raras (CIEMAT/CIBERER), Madrid, Spain.; Advanced Therapies Unit, Instituto De Investigación Sanitaria Fundación Jiménez Díaz (IIS-FJD, UAM), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Bautista+JM%22">Bautista JM</searchLink>; Translational Malaria Unit, 12 De Octubre Health Research Institute (imas12), Madrid, Spain.; Department of Biochemistry and Molecular Biology, Universidad Complutense De Madrid, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Monroy+F%22">Monroy F</searchLink>; Department of Physical Chemistry, Complutense University of Madrid, Madrid, Spain.; Translational Biophysics (imas12), Hospital Universitario 12 De Octubre, Madrid, Spain.
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