Macro-scale, scaffold-assisted model of the human bone marrow endosteal niche using hiPSC-vascularized osteoblastic organoids.

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Title: Macro-scale, scaffold-assisted model of the human bone marrow endosteal niche using hiPSC-vascularized osteoblastic organoids.
Authors: Li Q; Department of Biomedicine, University Hospital Basel, University of Basel, 4031 Basel, Switzerland; Department of Ophthalmology, The Affiliated Hospital of Guizhou Medical University, Guiyang, China., Nikolova MT; Department of Biosystems Science and Engineering, ETH Zürich, 4058 Basel, Switzerland., Zhang G; Department of Biomedicine, University Hospital Basel, University of Basel, 4031 Basel, Switzerland; Department of Biomedical Engineering, University of Basel, 4031 Basel, Switzerland., Cervenka I; Department of Biomedicine, University Hospital Basel, University of Basel, 4031 Basel, Switzerland; Swiss Institute of Bioinformatics, Basel, Switzerland., Valigi F; Department of Biomedicine, University Children's Hospital, University of Basel, 4031 Basel, Switzerland., Burri D; Department of Biomedicine, University Hospital Basel, University of Basel, 4031 Basel, Switzerland; Swiss Institute of Bioinformatics, Basel, Switzerland., Plantier E; Department of Biomedicine, University Hospital Basel, University of Basel, 4031 Basel, Switzerland., Mazzoleni A; Department of Biomedicine, University Hospital Basel, University of Basel, 4031 Basel, Switzerland; Department of Biomedical Engineering, University of Basel, 4031 Basel, Switzerland., Lamouline A; Department of Biomedicine, University Hospital Basel, University of Basel, 4031 Basel, Switzerland., Schwaller J; Department of Biomedicine, University Children's Hospital, University of Basel, 4031 Basel, Switzerland., Treutlein B; Department of Biosystems Science and Engineering, ETH Zürich, 4058 Basel, Switzerland., Martin I; Department of Biomedicine, University Hospital Basel, University of Basel, 4031 Basel, Switzerland; Department of Biomedical Engineering, University of Basel, 4031 Basel, Switzerland. Electronic address: ivan.martin@usb.ch., García-García A; Department of Biomedicine, University Hospital Basel, University of Basel, 4031 Basel, Switzerland. Electronic address: andres.garcia-garcia@unibas.ch.
Source: Cell stem cell [Cell Stem Cell] 2025 Dec 04; Vol. 32 (12), pp. 1941-1958.e8. Date of Electronic Publication: 2025 Nov 18.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101311472 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1875-9777 (Electronic) Linking ISSN: 18759777 NLM ISO Abbreviation: Cell Stem Cell Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1875-9777
DOI:10.1016/j.stem.2025.10.009