Heat-killed Lacticaseibacillus paracasei GMNL-346 exerts anti-oral cancer effect by suppressing cancer stem cell activity and rebalancing gut microbiota dysbiosis.
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| Title: | Heat-killed Lacticaseibacillus paracasei GMNL-346 exerts anti-oral cancer effect by suppressing cancer stem cell activity and rebalancing gut microbiota dysbiosis. |
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| Authors: | Chen YF; Institute of Clinical Medicine, School of Medicine, National Yang Ming Chiao Tung University, Taipei City, 112304, Taiwan; Division of Plastic and Reconstructive Surgery, Department of Surgery, Mackay Memorial Hospital, Taipei City, 104217, Taiwan. Electronic address: vanadium29@gmail.com., Fan CS; National Institute of Cancer Research, National Health Research Institutes, Miaoli County, 35053, Taiwan. Electronic address: change0935693367@hotmail.com., Hung YC; Department of Biomedical Sciences, Chung Shan Medical University, Taichung City, 402306, Taiwan. Electronic address: jackyhung1012@gmail.com., Chien PJ; Department of Biomedical Sciences, Chung Shan Medical University, Taichung City, 402306, Taiwan; Division of Thoracic Surgery, Department of Surgery, Changhua Christian Hospital, Changhua, Taiwan. Electronic address: chienpengju@gmail.com., Tsai WH; Research and Development Department, GenMont Biotech Incorporation, Tainan City, 741014, Taiwan. Electronic address: twh@genmont.com.tw., Yeh YT; Aging and Disease Prevention Research Center, Fooyin University, Kaohsiung City, 831301, Taiwan. Electronic address: glycosamine@yahoo.com.tw., Jhong JH; Department of Computer Science and Engineering, Yuan Ze University, Taoyuan City, 320315, Taiwan. Electronic address: jhihua.tw@gmail.com., Hsieh YN; Department of Biomedical Sciences, Chung Shan Medical University, Taichung City, 402306, Taiwan. Electronic address: xyun0615@gmail.com., Huang YH; Department of Biomedical Sciences, Chung Shan Medical University, Taichung City, 402306, Taiwan. Electronic address: bms0217062@gmail.com., Jan MS; Department of Microbiology and Immunology, School of Medicine, Chung Shan Medical University, Taichung City, 402306, Taiwan. Electronic address: msjan@csmu.edu.tw., Chang CF; Rayon Clinic, Taichung City, 412018, Taiwan; Department of Otorhinolaryngology, Head and Neck Surgery, Taichung Hospital Ministry of Health and Welfare, Taichung City, 403301, Taiwan; Rong Hsing Research Center For Translational Medicine, National Chung Hsing University, Taichung City, 402202, Taiwan. Electronic address: benglung@hotmail.com., Yang CY; Institute of Clinical Medicine, School of Medicine, National Yang Ming Chiao Tung University, Taipei City, 112304, Taiwan; Division of Nephrology, Department of Medicine, Taipei Veterans General Hospital, Taipei City, 112201, Taiwan; Center for Intelligent Drug Systems and Smart Bio-devices, National Yang Ming Chiao Tung University, Hsinchu 300193, Taiwan; Stem Cell Research Center, National Yang Ming Chiao Tung University, Taipei 112304, Taiwan. Electronic address: cyyang3@vghtpe.gov.tw., Chang WW; Department of Biomedical Sciences, Chung Shan Medical University, Taichung City, 402306, Taiwan; Department of Medical Research, Chung Shan Medical University Hospital, Taichung City, 402306, Taiwan. Electronic address: changww@csmu.edu.tw. |
| Source: | International journal of biological macromolecules [Int J Biol Macromol] 2025 Dec; Vol. 334 (Pt 1), pp. 149033. Date of Electronic Publication: 2025 Nov 17. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41260449 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Heat-killed Lacticaseibacillus paracasei GMNL-346 exerts anti-oral cancer effect by suppressing cancer stem cell activity and rebalancing gut microbiota dysbiosis. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Chen+YF%22">Chen YF</searchLink>; Institute of Clinical Medicine, School of Medicine, National Yang Ming Chiao Tung University, Taipei City, 112304, Taiwan; Division of Plastic and Reconstructive Surgery, Department of Surgery, Mackay Memorial Hospital, Taipei City, 104217, Taiwan. Electronic address: vanadium29@gmail.com.<br /><searchLink fieldCode="AU" term="%22Fan+CS%22">Fan CS</searchLink>; National Institute of Cancer Research, National Health Research Institutes, Miaoli County, 35053, Taiwan. Electronic address: change0935693367@hotmail.com.<br /><searchLink fieldCode="AU" term="%22Hung+YC%22">Hung YC</searchLink>; Department of Biomedical Sciences, Chung Shan Medical University, Taichung City, 402306, Taiwan. Electronic address: jackyhung1012@gmail.com.<br /><searchLink fieldCode="AU" term="%22Chien+PJ%22">Chien PJ</searchLink>; Department of Biomedical Sciences, Chung Shan Medical University, Taichung City, 402306, Taiwan; Division of Thoracic Surgery, Department of Surgery, Changhua Christian Hospital, Changhua, Taiwan. Electronic address: chienpengju@gmail.com.<br /><searchLink fieldCode="AU" term="%22Tsai+WH%22">Tsai WH</searchLink>; Research and Development Department, GenMont Biotech Incorporation, Tainan City, 741014, Taiwan. Electronic address: twh@genmont.com.tw.<br /><searchLink fieldCode="AU" term="%22Yeh+YT%22">Yeh YT</searchLink>; Aging and Disease Prevention Research Center, Fooyin University, Kaohsiung City, 831301, Taiwan. Electronic address: glycosamine@yahoo.com.tw.<br /><searchLink fieldCode="AU" term="%22Jhong+JH%22">Jhong JH</searchLink>; Department of Computer Science and Engineering, Yuan Ze University, Taoyuan City, 320315, Taiwan. Electronic address: jhihua.tw@gmail.com.<br /><searchLink fieldCode="AU" term="%22Hsieh+YN%22">Hsieh YN</searchLink>; Department of Biomedical Sciences, Chung Shan Medical University, Taichung City, 402306, Taiwan. Electronic address: xyun0615@gmail.com.<br /><searchLink fieldCode="AU" term="%22Huang+YH%22">Huang YH</searchLink>; Department of Biomedical Sciences, Chung Shan Medical University, Taichung City, 402306, Taiwan. Electronic address: bms0217062@gmail.com.<br /><searchLink fieldCode="AU" term="%22Jan+MS%22">Jan MS</searchLink>; Department of Microbiology and Immunology, School of Medicine, Chung Shan Medical University, Taichung City, 402306, Taiwan. Electronic address: msjan@csmu.edu.tw.<br /><searchLink fieldCode="AU" term="%22Chang+CF%22">Chang CF</searchLink>; Rayon Clinic, Taichung City, 412018, Taiwan; Department of Otorhinolaryngology, Head and Neck Surgery, Taichung Hospital Ministry of Health and Welfare, Taichung City, 403301, Taiwan; Rong Hsing Research Center For Translational Medicine, National Chung Hsing University, Taichung City, 402202, Taiwan. Electronic address: benglung@hotmail.com.<br /><searchLink fieldCode="AU" term="%22Yang+CY%22">Yang CY</searchLink>; Institute of Clinical Medicine, School of Medicine, National Yang Ming Chiao Tung University, Taipei City, 112304, Taiwan; Division of Nephrology, Department of Medicine, Taipei Veterans General Hospital, Taipei City, 112201, Taiwan; Center for Intelligent Drug Systems and Smart Bio-devices, National Yang Ming Chiao Tung University, Hsinchu 300193, Taiwan; Stem Cell Research Center, National Yang Ming Chiao Tung University, Taipei 112304, Taiwan. Electronic address: cyyang3@vghtpe.gov.tw.<br /><searchLink fieldCode="AU" term="%22Chang+WW%22">Chang WW</searchLink>; Department of Biomedical Sciences, Chung Shan Medical University, Taichung City, 402306, Taiwan; Department of Medical Research, Chung Shan Medical University Hospital, Taichung City, 402306, Taiwan. Electronic address: changww@csmu.edu.tw. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%227909578%22">International journal of biological macromolecules</searchLink> [Int J Biol Macromol] 2025 Dec; Vol. 334 (Pt 1), pp. 149033. <i>Date of Electronic Publication: </i>2025 Nov 17. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>7909578 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1879-0003 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201418130%22">01418130 </searchLink><i>NLM ISO Abbreviation: </i>Int J Biol Macromol <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41260449 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.ijbiomac.2025.149033 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 149033 Titles: – TitleFull: Heat-killed Lacticaseibacillus paracasei GMNL-346 exerts anti-oral cancer effect by suppressing cancer stem cell activity and rebalancing gut microbiota dysbiosis. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Chen YF – PersonEntity: Name: NameFull: Fan CS – PersonEntity: Name: NameFull: Hung YC – PersonEntity: Name: NameFull: Chien PJ – PersonEntity: Name: NameFull: Tsai WH – PersonEntity: Name: NameFull: Yeh YT – PersonEntity: Name: NameFull: Jhong JH – PersonEntity: Name: NameFull: Hsieh YN – PersonEntity: Name: NameFull: Huang YH – PersonEntity: Name: NameFull: Jan MS – PersonEntity: Name: NameFull: Chang CF – PersonEntity: Name: NameFull: Yang CY – PersonEntity: Name: NameFull: Chang WW IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 12 Text: 2025 Dec Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 1879-0003 Numbering: – Type: volume Value: 334 – Type: issue Value: Pt 1 Titles: – TitleFull: International journal of biological macromolecules Type: main |
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