A framework for the rigorous assessment of heterogeneous treatment effects from a single randomized controlled trial.

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Title: A framework for the rigorous assessment of heterogeneous treatment effects from a single randomized controlled trial.
Authors: Liang JW; Quantitative Sciences Unit, Section of Biostatistics, Department of Medicine, Stanford University School of Medicine, Stanford, CA, United States.; Division of Research, Kaiser Permanente Northern California, Pleasanton, CA, United States., Tian L; Department of Biomedical Data Science, Stanford University School of Medicine, Stanford, CA, United States., Tamura MK; Division of Nephrology, Department of Medicine, Stanford University School of Medicine, Stanford, CA, United States.; Geriatric Research and Education Clinical Center, Veterans Affairs Palo Alto Health Care System, Palo Alto, CA, United States., Montez-Rath M; Quantitative Sciences Unit, Section of Biostatistics, Department of Medicine, Stanford University School of Medicine, Stanford, CA, United States.; Division of Nephrology, Department of Medicine, Stanford University School of Medicine, Stanford, CA, United States., Frangakis C; Department of Biostatistics, Johns Hopkins School of Public Health, Baltimore, MD, United States., Charu V; Quantitative Sciences Unit, Section of Biostatistics, Department of Medicine, Stanford University School of Medicine, Stanford, CA, United States.; Department of Pathology, Stanford University School of Medicine, Stanford, CA, United States.
Source: American journal of epidemiology [Am J Epidemiol] 2026 Mar 17; Vol. 195 (4), pp. 1098-1107.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 7910653 Publication Model: Print Cited Medium: Internet ISSN: 1476-6256 (Electronic) Linking ISSN: 00029262 NLM ISO Abbreviation: Am J Epidemiol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1476-6256
DOI:10.1093/aje/kwaf253