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Decadelong low basal ganglia NAA/tCr from elevated tCr supports ATP depletion from mitochondrial dysfunction and neuroinflammation in Gulf War illness.

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Title: Decadelong low basal ganglia NAA/tCr from elevated tCr supports ATP depletion from mitochondrial dysfunction and neuroinflammation in Gulf War illness.
Authors: Cheshkov S; Department of Radiology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX, 75390-9113, USA.; Center for BrainHealth, University of Texas at Dallas, 2200 W. Mockingbird Lane, Dallas, TX, 75235-5451, USA., Krishnamurthy LC; Advanced Imaging Research Center (AIRC), University of Texas Southwestern Medical Center, 2201 Inwood Road, Dallas, TX, 75390-8568, USA.; Joseph Maxwell Cleland Atlanta VA Medical Center, 1670 Clairmont Road, Decatur, GA, 30033, USA.; Department of Radiology and Imaging Sciences, Emory University School of Medicine, 1364 Clifton Rd N E, Atlanta, GA, 30322, USA.; Center for Translational Research in Neuroimaging and Data Science, 55 Park Place NE, Atlanta, GA, 30303, USA., Chang A; Department of Radiology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX, 75390-9113, USA., Baek HM; Department of Radiology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX, 75390-9113, USA.; Lee Gil Ya Cancer and Diabetes Institute, Gachon University School of Medicine, 191 Hambakmoe-ro, Yeonsu-gu, Incheon Metropolitan City, 21936, South Korea., Ganji S; Department of Radiology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX, 75390-9113, USA.; Philips, Cambridge, MA, USA.; Department of Radiology, Mayo Clinic College of Medicine, Rochester, MN, USA., Babcock E; Department of Radiology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX, 75390-9113, USA., Spence JS; Department of Clinical Sciences, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX, 75390-8874, USA.; Center for BrainHealth, University of Texas at Dallas, 2200 W. Mockingbird Lane, Dallas, TX, 75235-5451, USA., Briggs RW; Department of Radiology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX, 75390-9113, USA.; Division of Epidemiology, Department of Internal Medicine, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX, 75390-8874, USA., Haley RW; Division of Epidemiology, Department of Internal Medicine, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX, 75390-8874, USA. Robert.Haley@UTSouthwestern.edu.; Epidemiology Unit, Division of Infectious Diseases and Geographic Medicine, Department of Internal Medicine, and Epidemiology Department, O'Donnell School of Public Health, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX, 75390-9113, USA. Robert.Haley@UTSouthwestern.edu.
Source: Scientific reports [Sci Rep] 2025 Nov 20; Vol. 15 (1), pp. 39741. Date of Electronic Publication: 2025 Nov 20.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Cheshkov+S%22">Cheshkov S</searchLink>; Department of Radiology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX, 75390-9113, USA.; Center for BrainHealth, University of Texas at Dallas, 2200 W. Mockingbird Lane, Dallas, TX, 75235-5451, USA.<br /><searchLink fieldCode="AU" term="%22Krishnamurthy+LC%22">Krishnamurthy LC</searchLink>; Advanced Imaging Research Center (AIRC), University of Texas Southwestern Medical Center, 2201 Inwood Road, Dallas, TX, 75390-8568, USA.; Joseph Maxwell Cleland Atlanta VA Medical Center, 1670 Clairmont Road, Decatur, GA, 30033, USA.; Department of Radiology and Imaging Sciences, Emory University School of Medicine, 1364 Clifton Rd N E, Atlanta, GA, 30322, USA.; Center for Translational Research in Neuroimaging and Data Science, 55 Park Place NE, Atlanta, GA, 30303, USA.<br /><searchLink fieldCode="AU" term="%22Chang+A%22">Chang A</searchLink>; Department of Radiology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX, 75390-9113, USA.<br /><searchLink fieldCode="AU" term="%22Baek+HM%22">Baek HM</searchLink>; Department of Radiology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX, 75390-9113, USA.; Lee Gil Ya Cancer and Diabetes Institute, Gachon University School of Medicine, 191 Hambakmoe-ro, Yeonsu-gu, Incheon Metropolitan City, 21936, South Korea.<br /><searchLink fieldCode="AU" term="%22Ganji+S%22">Ganji S</searchLink>; Department of Radiology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX, 75390-9113, USA.; Philips, Cambridge, MA, USA.; Department of Radiology, Mayo Clinic College of Medicine, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Babcock+E%22">Babcock E</searchLink>; Department of Radiology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX, 75390-9113, USA.<br /><searchLink fieldCode="AU" term="%22Spence+JS%22">Spence JS</searchLink>; Department of Clinical Sciences, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX, 75390-8874, USA.; Center for BrainHealth, University of Texas at Dallas, 2200 W. Mockingbird Lane, Dallas, TX, 75235-5451, USA.<br /><searchLink fieldCode="AU" term="%22Briggs+RW%22">Briggs RW</searchLink>; Department of Radiology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX, 75390-9113, USA.; Division of Epidemiology, Department of Internal Medicine, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX, 75390-8874, USA.<br /><searchLink fieldCode="AU" term="%22Haley+RW%22">Haley RW</searchLink>; Division of Epidemiology, Department of Internal Medicine, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX, 75390-8874, USA. Robert.Haley@UTSouthwestern.edu.; Epidemiology Unit, Division of Infectious Diseases and Geographic Medicine, Department of Internal Medicine, and Epidemiology Department, O'Donnell School of Public Health, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX, 75390-9113, USA. Robert.Haley@UTSouthwestern.edu.
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              Text: 2025 Nov 20
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