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Management of treatment-refractory opioid use disorder: a case-series of a modified maintenance protocol.

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Title: Management of treatment-refractory opioid use disorder: a case-series of a modified maintenance protocol.
Authors: Rioux W; Department of Medicine, Faculty of Medicine & Dentistry, University of Alberta, Edmonton, Canada., Weleff J; Department of Psychiatry, Faculty of Medicine & Dentistry, University of Alberta, Edmonton, Canada.; Neuroscience and Mental Health Institute, University of Alberta, Edmonton, Canada.; Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA., Zaganelli C; Alberta Health Services., Hayer L; Department of Medicine, Faculty of Medicine & Dentistry, University of Alberta, Edmonton, Canada., Ghosh SM; Department of Medicine, Faculty of Medicine & Dentistry, University of Alberta, Edmonton, Canada.; Department of General Internal Medicine, Faculty of Medicine & Dentistry, University of Alberta, Edmonton, Canada.; Neuroscience and Mental Health Institute, University of Alberta, Edmonton, Canada.; Department of Medicine, Cumming School Of Medicine, University of Calgary, Calgary, Canada.
Source: Journal of addictive diseases [J Addict Dis] 2026 Jul-Sep; Vol. 44 (3), pp. 351-357. Date of Electronic Publication: 2025 Nov 20.
Publication Type: Journal Article; Case Reports
Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 9107051 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1545-0848 (Electronic) Linking ISSN: 10550887 NLM ISO Abbreviation: J Addict Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Rioux+W%22">Rioux W</searchLink>; Department of Medicine, Faculty of Medicine & Dentistry, University of Alberta, Edmonton, Canada.<br /><searchLink fieldCode="AU" term="%22Weleff+J%22">Weleff J</searchLink>; Department of Psychiatry, Faculty of Medicine & Dentistry, University of Alberta, Edmonton, Canada.; Neuroscience and Mental Health Institute, University of Alberta, Edmonton, Canada.; Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Zaganelli+C%22">Zaganelli C</searchLink>; Alberta Health Services.<br /><searchLink fieldCode="AU" term="%22Hayer+L%22">Hayer L</searchLink>; Department of Medicine, Faculty of Medicine & Dentistry, University of Alberta, Edmonton, Canada.<br /><searchLink fieldCode="AU" term="%22Ghosh+SM%22">Ghosh SM</searchLink>; Department of Medicine, Faculty of Medicine & Dentistry, University of Alberta, Edmonton, Canada.; Department of General Internal Medicine, Faculty of Medicine & Dentistry, University of Alberta, Edmonton, Canada.; Neuroscience and Mental Health Institute, University of Alberta, Edmonton, Canada.; Department of Medicine, Cumming School Of Medicine, University of Calgary, Calgary, Canada.
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  Data: <searchLink fieldCode="JN" term="%229107051%22">Journal of addictive diseases</searchLink> [J Addict Dis] 2026 Jul-Sep; Vol. 44 (3), pp. 351-357. <i>Date of Electronic Publication: </i>2025 Nov 20.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Informa+Healthcare%22">Informa Healthcare </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9107051 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1545-0848 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210550887%22">10550887 </searchLink><i>NLM ISO Abbreviation: </i>J Addict Dis <i>Subsets: </i>MEDLINE
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        Value: 10.1080/10550887.2025.2581489
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              Text: 2026 Jul-Sep
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