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Clinical Complications, Mortality, and Healthcare Resource Utilization of Patients with Sickle Cell Disease with Recurrent Vaso-Occlusive Crises in Ontario, Canada: A Retrospective Cohort Study.

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Title: Clinical Complications, Mortality, and Healthcare Resource Utilization of Patients with Sickle Cell Disease with Recurrent Vaso-Occlusive Crises in Ontario, Canada: A Retrospective Cohort Study.
Authors: Lilly L; Vertex Pharmaceuticals Incorporated, 50 Northern Avenue, Boston, MA, 02210, USA. Lauren_lilly@vrtx.com., Udeze C; Vertex Pharmaceuticals Incorporated, 50 Northern Avenue, Boston, MA, 02210, USA., Nightingale N; IQVIA Solutions Canada Inc, Kanata, ON, Canada., Wang I; IQVIA Solutions Canada Inc, Kanata, ON, Canada., Murray J; IQVIA Solutions Canada Inc, Kanata, ON, Canada., Penaranda C; Vertex Pharmaceuticals Incorporated, 50 Northern Avenue, Boston, MA, 02210, USA., Neish CS; IQVIA Solutions Canada Inc, Kanata, ON, Canada., Li N; Vertex Pharmaceuticals Incorporated, 50 Northern Avenue, Boston, MA, 02210, USA., Kuo KHM; University of Toronto, Toronto, ON, Canada.
Source: Advances in therapy [Adv Ther] 2026 Jan; Vol. 43 (1), pp. 271-287. Date of Electronic Publication: 2025 Nov 21.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Health Communications Inc Country of Publication: United States NLM ID: 8611864 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1865-8652 (Electronic) Linking ISSN: 0741238X NLM ISO Abbreviation: Adv Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Clinical Complications, Mortality, and Healthcare Resource Utilization of Patients with Sickle Cell Disease with Recurrent Vaso-Occlusive Crises in Ontario, Canada: A Retrospective Cohort Study.
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  Data: <searchLink fieldCode="AU" term="%22Lilly+L%22">Lilly L</searchLink>; Vertex Pharmaceuticals Incorporated, 50 Northern Avenue, Boston, MA, 02210, USA. Lauren_lilly@vrtx.com.<br /><searchLink fieldCode="AU" term="%22Udeze+C%22">Udeze C</searchLink>; Vertex Pharmaceuticals Incorporated, 50 Northern Avenue, Boston, MA, 02210, USA.<br /><searchLink fieldCode="AU" term="%22Nightingale+N%22">Nightingale N</searchLink>; IQVIA Solutions Canada Inc, Kanata, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Wang+I%22">Wang I</searchLink>; IQVIA Solutions Canada Inc, Kanata, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Murray+J%22">Murray J</searchLink>; IQVIA Solutions Canada Inc, Kanata, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Penaranda+C%22">Penaranda C</searchLink>; Vertex Pharmaceuticals Incorporated, 50 Northern Avenue, Boston, MA, 02210, USA.<br /><searchLink fieldCode="AU" term="%22Neish+CS%22">Neish CS</searchLink>; IQVIA Solutions Canada Inc, Kanata, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Li+N%22">Li N</searchLink>; Vertex Pharmaceuticals Incorporated, 50 Northern Avenue, Boston, MA, 02210, USA.<br /><searchLink fieldCode="AU" term="%22Kuo+KHM%22">Kuo KHM</searchLink>; University of Toronto, Toronto, ON, Canada.
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  Data: <searchLink fieldCode="JN" term="%228611864%22">Advances in therapy</searchLink> [Adv Ther] 2026 Jan; Vol. 43 (1), pp. 271-287. <i>Date of Electronic Publication: </i>2025 Nov 21.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Health+Communications+Inc%22">Health Communications Inc </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>8611864 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1865-8652 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%220741238X%22">0741238X </searchLink><i>NLM ISO Abbreviation: </i>Adv Ther <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s12325-025-03411-4
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        Text: English
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        StartPage: 271
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      – TitleFull: Clinical Complications, Mortality, and Healthcare Resource Utilization of Patients with Sickle Cell Disease with Recurrent Vaso-Occlusive Crises in Ontario, Canada: A Retrospective Cohort Study.
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              Text: 2026 Jan
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