Remodeling of the immune microenvironment is linked to adverse outcome in pediatric T cell acute lymphoblastic leukemia.
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| Title: | Remodeling of the immune microenvironment is linked to adverse outcome in pediatric T cell acute lymphoblastic leukemia. |
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| Authors: | Wiggers CRM; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Cho EY; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Ozdemir M; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Bamgbose G; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA., Hegel J; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Frede J; Harvard Medical School, Boston, MA, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Warlitz F; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Heavican-Foral TB; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Pop I; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA., Shraim R; Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Pölönen P; Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA., Koch V; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Tran TH; Division of Pediatric Hematology-Oncology, Charles-Bruneau Cancer Center, Centre Hospitalier Universitaire Sainte-Justine, Montreal, QC, Canada., Mullighan CG; Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA., Teachey DT; Division of Oncology, Department of Pediatrics, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Bledsoe JR; Department of Pathology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA., Pikman Y; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.; Department of Hematology/Oncology, Boston Children's Hospital, Boston, MA, USA., Harris MH; Department of Pathology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA., Place AE; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.; Department of Hematology/Oncology, Boston Children's Hospital, Boston, MA, USA., Silverman LB; Division of Pediatric Hematology, Oncology and Stem Cell Transplantation, Columbia University Irving Medical Center, New York, NY, USA., Lohr JG; Harvard Medical School, Boston, MA, USA. jens.lohr@hci.utah.edu.; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA. jens.lohr@hci.utah.edu.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. jens.lohr@hci.utah.edu.; Broad Institute of MIT and Harvard, Cambridge, MA, USA. jens.lohr@hci.utah.edu., Knoechel B; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. birgit.knoechel@hci.utah.edu.; Harvard Medical School, Boston, MA, USA. birgit.knoechel@hci.utah.edu.; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA. birgit.knoechel@hci.utah.edu.; Department of Hematology/Oncology, Boston Children's Hospital, Boston, MA, USA. birgit.knoechel@hci.utah.edu.; Broad Institute of MIT and Harvard, Cambridge, MA, USA. birgit.knoechel@hci.utah.edu. |
| Source: | Nature communications [Nat Commun] 2025 Nov 21; Vol. 16 (1), pp. 10263. Date of Electronic Publication: 2025 Nov 21. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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