Tanshinone IIA Promotes Hippocampal Neurogenesis in ApoE-/- Mice Through cAMP/PKA/CREB/BDNF Signaling Pathway.

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Title: Tanshinone IIA Promotes Hippocampal Neurogenesis in ApoE-/- Mice Through cAMP/PKA/CREB/BDNF Signaling Pathway.
Authors: Yang Z; Department of Human Anatomy, Histology and Embryology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, 76 Yanta West Road, Xi'an, Shaanxi, 710061, China.; Qide College, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, 710061, China., Peng X; Department of Human Anatomy, Histology and Embryology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, 76 Yanta West Road, Xi'an, Shaanxi, 710061, China., Zhang X; Department of Human Anatomy, Histology and Embryology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, 76 Yanta West Road, Xi'an, Shaanxi, 710061, China., Guo H; Department of Human Anatomy, Histology and Embryology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, 76 Yanta West Road, Xi'an, Shaanxi, 710061, China., Li Z; Department of Human Anatomy, Histology and Embryology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, 76 Yanta West Road, Xi'an, Shaanxi, 710061, China.; Zonglian College, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, 710061, China., Wu X; Department of Human Anatomy, Histology and Embryology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, 76 Yanta West Road, Xi'an, Shaanxi, 710061, China., Zhao M; Department of Human Anatomy, Histology and Embryology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, 76 Yanta West Road, Xi'an, Shaanxi, 710061, China.; Zonglian College, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, 710061, China., Ruganzu JB; Department of Human Anatomy, Histology and Embryology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, 76 Yanta West Road, Xi'an, Shaanxi, 710061, China., Zhai C; Department of Human Anatomy, Histology and Embryology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, 76 Yanta West Road, Xi'an, Shaanxi, 710061, China.; Qide College, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, 710061, China., Ji S; Department of Human Anatomy, Histology and Embryology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, 76 Yanta West Road, Xi'an, Shaanxi, 710061, China., Yang W; Department of Human Anatomy, Histology and Embryology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, 76 Yanta West Road, Xi'an, Shaanxi, 710061, China. wn_yang@mail.xjtu.edu.cn.
Source: Molecular neurobiology [Mol Neurobiol] 2025 Nov 22; Vol. 63 (1), pp. 144. Date of Electronic Publication: 2025 Nov 22.
Publication Type: Journal Article
Journal Info: Publisher: Humana Press Country of Publication: United States NLM ID: 8900963 Publication Model: Electronic Cited Medium: Internet ISSN: 1559-1182 (Electronic) Linking ISSN: 08937648 NLM ISO Abbreviation: Mol Neurobiol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1559-1182
DOI:10.1007/s12035-025-05467-3