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Targeting SERPINB3-MAPK axis-mediated cuproptosis resistance enhances the response to antitumor immunotherapy.

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Title: Targeting SERPINB3-MAPK axis-mediated cuproptosis resistance enhances the response to antitumor immunotherapy.
Authors: Huang XX; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China.; Department of Hepatobiliary Pancreatic Surgery, Fuzhou University Affiliated Provincial Hospital, Fujian Provincial Hospital, No.134 East Street, Fuzhou, 350001, China., Xie CK; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China.; Department of Hepatobiliary Pancreatic Surgery, Fuzhou University Affiliated Provincial Hospital, Fujian Provincial Hospital, No.134 East Street, Fuzhou, 350001, China., Mo YC; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China.; Affiliated Gaozhou People's Hospital, Guangdong Medical University, Gaozhou, 525200, China., Li W; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China.; Department of Vascular Surgery, The Second Hospital of Yinzhou District, Ningbo, Zhejiang Province, 315000, China., Wu YD; Department of Hepatobiliary Pancreatic Surgery, Fuzhou University Affiliated Provincial Hospital, Fujian Provincial Hospital, No.134 East Street, Fuzhou, 350001, China., Li ZY; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China.; Department of Hepatobiliary Pancreatic Surgery, Fuzhou University Affiliated Provincial Hospital, Fujian Provincial Hospital, No.134 East Street, Fuzhou, 350001, China., Zhang HX; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China.; Department of Hepatobiliary Pancreatic Surgery, Fuzhou University Affiliated Provincial Hospital, Fujian Provincial Hospital, No.134 East Street, Fuzhou, 350001, China., Li G; Department of Hepatobiliary Surgery, Fujian Institute of Hepatobiliary Surgery, Fujian Medical University Union Hospital, Fuzhou, 350001, China., Jin L; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China., Lin XQ; Department of Hepatobiliary Pancreatic Surgery, Fuzhou University Affiliated Provincial Hospital, Fujian Provincial Hospital, No.134 East Street, Fuzhou, 350001, China., Hu JF; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China.; Department of Hepatobiliary Pancreatic Surgery, Fuzhou University Affiliated Provincial Hospital, Fujian Provincial Hospital, No.134 East Street, Fuzhou, 350001, China., Chen YH; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China.; Department of Hepatobiliary Pancreatic Surgery, Fuzhou University Affiliated Provincial Hospital, Fujian Provincial Hospital, No.134 East Street, Fuzhou, 350001, China., Lin HY; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China.; Department of Hepatobiliary Pancreatic Surgery, Fuzhou University Affiliated Provincial Hospital, Fujian Provincial Hospital, No.134 East Street, Fuzhou, 350001, China., Zhu SC; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China.; Department of Hepatobiliary Pancreatic Surgery, Fuzhou University Affiliated Provincial Hospital, Fujian Provincial Hospital, No.134 East Street, Fuzhou, 350001, China., Lu JP; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China.; Department of Hepatobiliary Pancreatic Surgery, Fuzhou University Affiliated Provincial Hospital, Fujian Provincial Hospital, No.134 East Street, Fuzhou, 350001, China., Zhu HJ; Institute of Materials Research and Engineering A*STAR (Agency for Science, Technology and Research, 2 Fusionopolis Way, Innovis, Singapore, 138634, Singapore., Wang WW; Institute of Materials Research and Engineering A*STAR (Agency for Science, Technology and Research, 2 Fusionopolis Way, Innovis, Singapore, 138634, Singapore., Huang Y; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China., Wang ZW; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China.; Department of Hepatobiliary Pancreatic Surgery, Fuzhou University Affiliated Provincial Hospital, Fujian Provincial Hospital, No.134 East Street, Fuzhou, 350001, China., Huang L; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China.; Department of Hepatobiliary Pancreatic Surgery, Fuzhou University Affiliated Provincial Hospital, Fujian Provincial Hospital, No.134 East Street, Fuzhou, 350001, China., Wang DF; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China. 251487848@qq.com., Tian YF; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China.; Department of Hepatobiliary Pancreatic Surgery, Fuzhou University Affiliated Provincial Hospital, Fujian Provincial Hospital, No.134 East Street, Fuzhou, 350001, China., Liao CY; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China. Deppievic@outlook.com.; Department of Hepatobiliary Pancreatic Surgery, Fuzhou University Affiliated Provincial Hospital, Fujian Provincial Hospital, No.134 East Street, Fuzhou, 350001, China. Deppievic@outlook.com., Chen S; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China. wawljwalj@163.com.; Department of Hepatobiliary Pancreatic Surgery, Fuzhou University Affiliated Provincial Hospital, Fujian Provincial Hospital, No.134 East Street, Fuzhou, 350001, China. wawljwalj@163.com.
Source: Molecular cancer [Mol Cancer] 2025 Nov 22; Vol. 25 (1). Date of Electronic Publication: 2025 Nov 22.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101147698 Publication Model: Electronic Cited Medium: Internet ISSN: 1476-4598 (Electronic) Linking ISSN: 14764598 NLM ISO Abbreviation: Mol Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Targeting SERPINB3-MAPK axis-mediated cuproptosis resistance enhances the response to antitumor immunotherapy.
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  Data: <searchLink fieldCode="AU" term="%22Huang+XX%22">Huang XX</searchLink>; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China.; Department of Hepatobiliary Pancreatic Surgery, Fuzhou University Affiliated Provincial Hospital, Fujian Provincial Hospital, No.134 East Street, Fuzhou, 350001, China.<br /><searchLink fieldCode="AU" term="%22Xie+CK%22">Xie CK</searchLink>; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China.; Department of Hepatobiliary Pancreatic Surgery, Fuzhou University Affiliated Provincial Hospital, Fujian Provincial Hospital, No.134 East Street, Fuzhou, 350001, China.<br /><searchLink fieldCode="AU" term="%22Mo+YC%22">Mo YC</searchLink>; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China.; Affiliated Gaozhou People's Hospital, Guangdong Medical University, Gaozhou, 525200, China.<br /><searchLink fieldCode="AU" term="%22Li+W%22">Li W</searchLink>; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China.; Department of Vascular Surgery, The Second Hospital of Yinzhou District, Ningbo, Zhejiang Province, 315000, China.<br /><searchLink fieldCode="AU" term="%22Wu+YD%22">Wu YD</searchLink>; Department of Hepatobiliary Pancreatic Surgery, Fuzhou University Affiliated Provincial Hospital, Fujian Provincial Hospital, No.134 East Street, Fuzhou, 350001, China.<br /><searchLink fieldCode="AU" term="%22Li+ZY%22">Li ZY</searchLink>; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China.; Department of Hepatobiliary Pancreatic Surgery, Fuzhou University Affiliated Provincial Hospital, Fujian Provincial Hospital, No.134 East Street, Fuzhou, 350001, China.<br /><searchLink fieldCode="AU" term="%22Zhang+HX%22">Zhang HX</searchLink>; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China.; Department of Hepatobiliary Pancreatic Surgery, Fuzhou University Affiliated Provincial Hospital, Fujian Provincial Hospital, No.134 East Street, Fuzhou, 350001, China.<br /><searchLink fieldCode="AU" term="%22Li+G%22">Li G</searchLink>; Department of Hepatobiliary Surgery, Fujian Institute of Hepatobiliary Surgery, Fujian Medical University Union Hospital, Fuzhou, 350001, China.<br /><searchLink fieldCode="AU" term="%22Jin+L%22">Jin L</searchLink>; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China.<br /><searchLink fieldCode="AU" term="%22Lin+XQ%22">Lin XQ</searchLink>; Department of Hepatobiliary Pancreatic Surgery, Fuzhou University Affiliated Provincial Hospital, Fujian Provincial Hospital, No.134 East Street, Fuzhou, 350001, China.<br /><searchLink fieldCode="AU" term="%22Hu+JF%22">Hu JF</searchLink>; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China.; Department of Hepatobiliary Pancreatic Surgery, Fuzhou University Affiliated Provincial Hospital, Fujian Provincial Hospital, No.134 East Street, Fuzhou, 350001, China.<br /><searchLink fieldCode="AU" term="%22Chen+YH%22">Chen YH</searchLink>; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China.; Department of Hepatobiliary Pancreatic Surgery, Fuzhou University Affiliated Provincial Hospital, Fujian Provincial Hospital, No.134 East Street, Fuzhou, 350001, China.<br /><searchLink fieldCode="AU" term="%22Lin+HY%22">Lin HY</searchLink>; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China.; Department of Hepatobiliary Pancreatic Surgery, Fuzhou University Affiliated Provincial Hospital, Fujian Provincial Hospital, No.134 East Street, Fuzhou, 350001, China.<br /><searchLink fieldCode="AU" term="%22Zhu+SC%22">Zhu SC</searchLink>; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China.; Department of Hepatobiliary Pancreatic Surgery, Fuzhou University Affiliated Provincial Hospital, Fujian Provincial Hospital, No.134 East Street, Fuzhou, 350001, China.<br /><searchLink fieldCode="AU" term="%22Lu+JP%22">Lu JP</searchLink>; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China.; Department of Hepatobiliary Pancreatic Surgery, Fuzhou University Affiliated Provincial Hospital, Fujian Provincial Hospital, No.134 East Street, Fuzhou, 350001, China.<br /><searchLink fieldCode="AU" term="%22Zhu+HJ%22">Zhu HJ</searchLink>; Institute of Materials Research and Engineering A*STAR (Agency for Science, Technology and Research, 2 Fusionopolis Way, Innovis, Singapore, 138634, Singapore.<br /><searchLink fieldCode="AU" term="%22Wang+WW%22">Wang WW</searchLink>; Institute of Materials Research and Engineering A*STAR (Agency for Science, Technology and Research, 2 Fusionopolis Way, Innovis, Singapore, 138634, Singapore.<br /><searchLink fieldCode="AU" term="%22Huang+Y%22">Huang Y</searchLink>; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China.<br /><searchLink fieldCode="AU" term="%22Wang+ZW%22">Wang ZW</searchLink>; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China.; Department of Hepatobiliary Pancreatic Surgery, Fuzhou University Affiliated Provincial Hospital, Fujian Provincial Hospital, No.134 East Street, Fuzhou, 350001, China.<br /><searchLink fieldCode="AU" term="%22Huang+L%22">Huang L</searchLink>; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China.; Department of Hepatobiliary Pancreatic Surgery, Fuzhou University Affiliated Provincial Hospital, Fujian Provincial Hospital, No.134 East Street, Fuzhou, 350001, China.<br /><searchLink fieldCode="AU" term="%22Wang+DF%22">Wang DF</searchLink>; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China. 251487848@qq.com.<br /><searchLink fieldCode="AU" term="%22Tian+YF%22">Tian YF</searchLink>; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China.; Department of Hepatobiliary Pancreatic Surgery, Fuzhou University Affiliated Provincial Hospital, Fujian Provincial Hospital, No.134 East Street, Fuzhou, 350001, China.<br /><searchLink fieldCode="AU" term="%22Liao+CY%22">Liao CY</searchLink>; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China. Deppievic@outlook.com.; Department of Hepatobiliary Pancreatic Surgery, Fuzhou University Affiliated Provincial Hospital, Fujian Provincial Hospital, No.134 East Street, Fuzhou, 350001, China. Deppievic@outlook.com.<br /><searchLink fieldCode="AU" term="%22Chen+S%22">Chen S</searchLink>; Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China. wawljwalj@163.com.; Department of Hepatobiliary Pancreatic Surgery, Fuzhou University Affiliated Provincial Hospital, Fujian Provincial Hospital, No.134 East Street, Fuzhou, 350001, China. wawljwalj@163.com.
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  Data: <searchLink fieldCode="JN" term="%22101147698%22">Molecular cancer</searchLink> [Mol Cancer] 2025 Nov 22; Vol. 25 (1). <i>Date of Electronic Publication: </i>2025 Nov 22.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101147698 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-4598 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214764598%22">14764598 </searchLink><i>NLM ISO Abbreviation: </i>Mol Cancer <i>Subsets: </i>MEDLINE
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