Artificial intelligence for TNM staging in NSCLC: a critical appraisal of segmentation utility in [1⁸F]FDG PET/CT.

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Title: Artificial intelligence for TNM staging in NSCLC: a critical appraisal of segmentation utility in [1⁸F]FDG PET/CT.
Authors: Heimer MM; Department of Radiology, LMU University Hospital, LMU Munich, Munich, Germany. maurice.heimer@med.uni-muenchen.de., Dexl J; Department of Radiology, LMU University Hospital, LMU Munich, Munich, Germany.; Munich Center for Machine Learning (MCML), Munich, Germany., Ta J; Department of Radiology, LMU University Hospital, LMU Munich, Munich, Germany., Ebner R; Department of Radiology, LMU University Hospital, LMU Munich, Munich, Germany., Herr FL; Department of Radiology, LMU University Hospital, LMU Munich, Munich, Germany., Orasanin L; Department of Radiology, LMU University Hospital, LMU Munich, Munich, Germany.; Munich Center for Machine Learning (MCML), Munich, Germany., Jeblick K; Department of Radiology, LMU University Hospital, LMU Munich, Munich, Germany.; Munich Center for Machine Learning (MCML), Munich, Germany.; Comprehensive Pneumology Center (CPC-M), Member of the German Center for Lung Research (DZL), Munich, Germany., Adams LC; Department of Radiology, TUM University Hospital, TU Munich, Munich, Germany., Sundar LKS; Department of Radiology, LMU University Hospital, LMU Munich, Munich, Germany., Tufman A; Comprehensive Pneumology Center (CPC-M), Member of the German Center for Lung Research (DZL), Munich, Germany.; Department of Medicine V, LMU University Hospital, LMU Munich, Munich, Germany, and Bavarian Center for Cancer Research (BZKF), Munich, Germany., Werner RA; Department of Nuclear Medicine, LMU University Hospital, LMU Munich, Munich, Germany.; The Russell H. Morgan Department of Radiology and Radiological Sciences, Division of Nuclear Medicine and Molecular Imaging, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Sheikh G; Department of Nuclear Medicine, LMU University Hospital, LMU Munich, Munich, Germany., Ricke J; Department of Radiology, LMU University Hospital, LMU Munich, Munich, Germany., Ingrisch M; Department of Radiology, LMU University Hospital, LMU Munich, Munich, Germany.; Munich Center for Machine Learning (MCML), Munich, Germany., Fabritius MP; Department of Radiology, LMU University Hospital, LMU Munich, Munich, Germany., Cyran CC; Department of Radiology, LMU University Hospital, LMU Munich, Munich, Germany.
Source: European journal of nuclear medicine and molecular imaging [Eur J Nucl Med Mol Imaging] 2026 Apr; Vol. 53 (5), pp. 3117-3127. Date of Electronic Publication: 2025 Nov 23.
Publication Type: Journal Article
Journal Info: Publisher: Springer-Verlag Berlin Country of Publication: Germany NLM ID: 101140988 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1619-7089 (Electronic) Linking ISSN: 16197070 NLM ISO Abbreviation: Eur J Nucl Med Mol Imaging Subsets: MEDLINE
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  Data: Artificial intelligence for TNM staging in NSCLC: a critical appraisal of segmentation utility in [<superscript>1</superscript>⁸F]FDG PET/CT.
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  Data: <searchLink fieldCode="AU" term="%22Heimer+MM%22">Heimer MM</searchLink>; Department of Radiology, LMU University Hospital, LMU Munich, Munich, Germany. maurice.heimer@med.uni-muenchen.de.<br /><searchLink fieldCode="AU" term="%22Dexl+J%22">Dexl J</searchLink>; Department of Radiology, LMU University Hospital, LMU Munich, Munich, Germany.; Munich Center for Machine Learning (MCML), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Ta+J%22">Ta J</searchLink>; Department of Radiology, LMU University Hospital, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Ebner+R%22">Ebner R</searchLink>; Department of Radiology, LMU University Hospital, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Herr+FL%22">Herr FL</searchLink>; Department of Radiology, LMU University Hospital, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Orasanin+L%22">Orasanin L</searchLink>; Department of Radiology, LMU University Hospital, LMU Munich, Munich, Germany.; Munich Center for Machine Learning (MCML), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Jeblick+K%22">Jeblick K</searchLink>; Department of Radiology, LMU University Hospital, LMU Munich, Munich, Germany.; Munich Center for Machine Learning (MCML), Munich, Germany.; Comprehensive Pneumology Center (CPC-M), Member of the German Center for Lung Research (DZL), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Adams+LC%22">Adams LC</searchLink>; Department of Radiology, TUM University Hospital, TU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Sundar+LKS%22">Sundar LKS</searchLink>; Department of Radiology, LMU University Hospital, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Tufman+A%22">Tufman A</searchLink>; Comprehensive Pneumology Center (CPC-M), Member of the German Center for Lung Research (DZL), Munich, Germany.; Department of Medicine V, LMU University Hospital, LMU Munich, Munich, Germany, and Bavarian Center for Cancer Research (BZKF), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Werner+RA%22">Werner RA</searchLink>; Department of Nuclear Medicine, LMU University Hospital, LMU Munich, Munich, Germany.; The Russell H. Morgan Department of Radiology and Radiological Sciences, Division of Nuclear Medicine and Molecular Imaging, Johns Hopkins University School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Sheikh+G%22">Sheikh G</searchLink>; Department of Nuclear Medicine, LMU University Hospital, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Ricke+J%22">Ricke J</searchLink>; Department of Radiology, LMU University Hospital, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Ingrisch+M%22">Ingrisch M</searchLink>; Department of Radiology, LMU University Hospital, LMU Munich, Munich, Germany.; Munich Center for Machine Learning (MCML), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Fabritius+MP%22">Fabritius MP</searchLink>; Department of Radiology, LMU University Hospital, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Cyran+CC%22">Cyran CC</searchLink>; Department of Radiology, LMU University Hospital, LMU Munich, Munich, Germany.
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      – TitleFull: Artificial intelligence for TNM staging in NSCLC: a critical appraisal of segmentation utility in [1⁸F]FDG PET/CT.
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