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MITF, TFEB, and TFE3 drive distinct adaptive gene expression programs and immune infiltration in melanoma.

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Title: MITF, TFEB, and TFE3 drive distinct adaptive gene expression programs and immune infiltration in melanoma.
Authors: Dias D; Ludwig Institute for Cancer Research, Nuffield Department of Clinical Medicine, University of Oxford, Old Road Campus Research Building, Old Road Campus, Headington, Oxford OX3 7DQ, UK., Oliveira E; Ludwig Institute for Cancer Research, Nuffield Department of Clinical Medicine, University of Oxford, Old Road Campus Research Building, Old Road Campus, Headington, Oxford OX3 7DQ, UK., Martí-Díaz R; Department of Biochemistry and Molecular Biology A, School of Biology, University of Murcia, Instituto Murciano de Investigación Biosanitaria (IMIB), 30120 Murcia, Spain., Andrews S; Ludwig Institute for Cancer Research, Nuffield Department of Clinical Medicine, University of Oxford, Old Road Campus Research Building, Old Road Campus, Headington, Oxford OX3 7DQ, UK., Chocarro-Calvo A; Area of Physiology, Faculty Health Sciences, University Rey Juan Carlos, Alcorcón, 28922 Madrid, Spain., Bellini A; Ludwig Institute for Cancer Research, Nuffield Department of Clinical Medicine, University of Oxford, Old Road Campus Research Building, Old Road Campus, Headington, Oxford OX3 7DQ, UK., Mosteo L; Ludwig Institute for Cancer Research, Nuffield Department of Clinical Medicine, University of Oxford, Old Road Campus Research Building, Old Road Campus, Headington, Oxford OX3 7DQ, UK., García YV; Ludwig Institute for Cancer Research, Nuffield Department of Clinical Medicine, University of Oxford, Old Road Campus Research Building, Old Road Campus, Headington, Oxford OX3 7DQ, UK., Chauhan J; Ludwig Institute for Cancer Research, Nuffield Department of Clinical Medicine, University of Oxford, Old Road Campus Research Building, Old Road Campus, Headington, Oxford OX3 7DQ, UK., Li L; Ludwig Institute for Cancer Research, Nuffield Department of Clinical Medicine, University of Oxford, Old Road Campus Research Building, Old Road Campus, Headington, Oxford OX3 7DQ, UK., García-Martinez JM; Area of Physiology, Faculty Health Sciences, University Rey Juan Carlos, Alcorcón, 28922 Madrid, Spain., Rodriguez-López JN; Department of Biochemistry and Molecular Biology A, School of Biology, University of Murcia, Instituto Murciano de Investigación Biosanitaria (IMIB), 30120 Murcia, Spain., Maria-Engler SS; Department of Clinical and Toxicological Analysis School of Pharmaceutical Sciences, University of São Paulo, São Paulo 05508-000, Brazil., Kenny C; Department of Surgery, Carver College of Medicine, University of Iowa, Iowa City, IA, USA; Holden Comprehensive Cancer Center, Carver College of Medicine, University of Iowa, Iowa City, IA, USA., Martínez-Useros J; Area of Physiology, Faculty Health Sciences, University Rey Juan Carlos, Alcorcón, 28922 Madrid, Spain., García-Jiménez C; Area of Physiology, Faculty Health Sciences, University Rey Juan Carlos, Alcorcón, 28922 Madrid, Spain., Sanchez-Del-Campo L; Department of Biochemistry and Molecular Biology A, School of Biology, University of Murcia, Instituto Murciano de Investigación Biosanitaria (IMIB), 30120 Murcia, Spain., Louphrasitthiphol P; Ludwig Institute for Cancer Research, Nuffield Department of Clinical Medicine, University of Oxford, Old Road Campus Research Building, Old Road Campus, Headington, Oxford OX3 7DQ, UK. Electronic address: pakavarin.louphrasitthiphol@ludwig.ox.ac.uk., Goding CR; Ludwig Institute for Cancer Research, Nuffield Department of Clinical Medicine, University of Oxford, Old Road Campus Research Building, Old Road Campus, Headington, Oxford OX3 7DQ, UK. Electronic address: colin.goding@ludwig.ox.ac.uk.
Source: Cell reports [Cell Rep] 2025 Dec 23; Vol. 44 (12), pp. 116499. Date of Electronic Publication: 2025 Nov 22.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE
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  Data: MITF, TFEB, and TFE3 drive distinct adaptive gene expression programs and immune infiltration in melanoma.
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  Data: <searchLink fieldCode="AU" term="%22Dias+D%22">Dias D</searchLink>; Ludwig Institute for Cancer Research, Nuffield Department of Clinical Medicine, University of Oxford, Old Road Campus Research Building, Old Road Campus, Headington, Oxford OX3 7DQ, UK.<br /><searchLink fieldCode="AU" term="%22Oliveira+E%22">Oliveira E</searchLink>; Ludwig Institute for Cancer Research, Nuffield Department of Clinical Medicine, University of Oxford, Old Road Campus Research Building, Old Road Campus, Headington, Oxford OX3 7DQ, UK.<br /><searchLink fieldCode="AU" term="%22Martí-Díaz+R%22">Martí-Díaz R</searchLink>; Department of Biochemistry and Molecular Biology A, School of Biology, University of Murcia, Instituto Murciano de Investigación Biosanitaria (IMIB), 30120 Murcia, Spain.<br /><searchLink fieldCode="AU" term="%22Andrews+S%22">Andrews S</searchLink>; Ludwig Institute for Cancer Research, Nuffield Department of Clinical Medicine, University of Oxford, Old Road Campus Research Building, Old Road Campus, Headington, Oxford OX3 7DQ, UK.<br /><searchLink fieldCode="AU" term="%22Chocarro-Calvo+A%22">Chocarro-Calvo A</searchLink>; Area of Physiology, Faculty Health Sciences, University Rey Juan Carlos, Alcorcón, 28922 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Bellini+A%22">Bellini A</searchLink>; Ludwig Institute for Cancer Research, Nuffield Department of Clinical Medicine, University of Oxford, Old Road Campus Research Building, Old Road Campus, Headington, Oxford OX3 7DQ, UK.<br /><searchLink fieldCode="AU" term="%22Mosteo+L%22">Mosteo L</searchLink>; Ludwig Institute for Cancer Research, Nuffield Department of Clinical Medicine, University of Oxford, Old Road Campus Research Building, Old Road Campus, Headington, Oxford OX3 7DQ, UK.<br /><searchLink fieldCode="AU" term="%22García+YV%22">García YV</searchLink>; Ludwig Institute for Cancer Research, Nuffield Department of Clinical Medicine, University of Oxford, Old Road Campus Research Building, Old Road Campus, Headington, Oxford OX3 7DQ, UK.<br /><searchLink fieldCode="AU" term="%22Chauhan+J%22">Chauhan J</searchLink>; Ludwig Institute for Cancer Research, Nuffield Department of Clinical Medicine, University of Oxford, Old Road Campus Research Building, Old Road Campus, Headington, Oxford OX3 7DQ, UK.<br /><searchLink fieldCode="AU" term="%22Li+L%22">Li L</searchLink>; Ludwig Institute for Cancer Research, Nuffield Department of Clinical Medicine, University of Oxford, Old Road Campus Research Building, Old Road Campus, Headington, Oxford OX3 7DQ, UK.<br /><searchLink fieldCode="AU" term="%22García-Martinez+JM%22">García-Martinez JM</searchLink>; Area of Physiology, Faculty Health Sciences, University Rey Juan Carlos, Alcorcón, 28922 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Rodriguez-López+JN%22">Rodriguez-López JN</searchLink>; Department of Biochemistry and Molecular Biology A, School of Biology, University of Murcia, Instituto Murciano de Investigación Biosanitaria (IMIB), 30120 Murcia, Spain.<br /><searchLink fieldCode="AU" term="%22Maria-Engler+SS%22">Maria-Engler SS</searchLink>; Department of Clinical and Toxicological Analysis School of Pharmaceutical Sciences, University of São Paulo, São Paulo 05508-000, Brazil.<br /><searchLink fieldCode="AU" term="%22Kenny+C%22">Kenny C</searchLink>; Department of Surgery, Carver College of Medicine, University of Iowa, Iowa City, IA, USA; Holden Comprehensive Cancer Center, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Martínez-Useros+J%22">Martínez-Useros J</searchLink>; Area of Physiology, Faculty Health Sciences, University Rey Juan Carlos, Alcorcón, 28922 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22García-Jiménez+C%22">García-Jiménez C</searchLink>; Area of Physiology, Faculty Health Sciences, University Rey Juan Carlos, Alcorcón, 28922 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Sanchez-Del-Campo+L%22">Sanchez-Del-Campo L</searchLink>; Department of Biochemistry and Molecular Biology A, School of Biology, University of Murcia, Instituto Murciano de Investigación Biosanitaria (IMIB), 30120 Murcia, Spain.<br /><searchLink fieldCode="AU" term="%22Louphrasitthiphol+P%22">Louphrasitthiphol P</searchLink>; Ludwig Institute for Cancer Research, Nuffield Department of Clinical Medicine, University of Oxford, Old Road Campus Research Building, Old Road Campus, Headington, Oxford OX3 7DQ, UK. Electronic address: pakavarin.louphrasitthiphol@ludwig.ox.ac.uk.<br /><searchLink fieldCode="AU" term="%22Goding+CR%22">Goding CR</searchLink>; Ludwig Institute for Cancer Research, Nuffield Department of Clinical Medicine, University of Oxford, Old Road Campus Research Building, Old Road Campus, Headington, Oxford OX3 7DQ, UK. Electronic address: colin.goding@ludwig.ox.ac.uk.
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