Arginine Metabolism Supports De Novo Pyrimidine Biosynthesis to Block DNA Damage and Maintain Epstein-Barr Virus Latency.

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Title: Arginine Metabolism Supports De Novo Pyrimidine Biosynthesis to Block DNA Damage and Maintain Epstein-Barr Virus Latency.
Authors: White S; Division of Infectious Diseases, Department of Medicine, Brigham and Women's Hospital, 181 Longwood Avenue, Boston, MA 02115, USA.; Broad Institute, Cambridge, MA 02142, USA., Liao Y; Division of Infectious Diseases, Department of Medicine, Brigham and Women's Hospital, 181 Longwood Avenue, Boston, MA 02115, USA.; Broad Institute, Cambridge, MA 02142, USA., Burton EM; Division of Infectious Diseases, Department of Medicine, Brigham and Women's Hospital, 181 Longwood Avenue, Boston, MA 02115, USA.; Broad Institute, Cambridge, MA 02142, USA., Asara JM; Division of Signal Transduction, Beth Israel Deaconess Medical Center and Department of Medicine, Boston, MA 02215, USA., Gewurz BE; Division of Infectious Diseases, Department of Medicine, Brigham and Women's Hospital, 181 Longwood Avenue, Boston, MA 02115, USA.; Broad Institute, Cambridge, MA 02142, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Oct 21. Date of Electronic Publication: 2025 Oct 21.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22White+S%22">White S</searchLink>; Division of Infectious Diseases, Department of Medicine, Brigham and Women's Hospital, 181 Longwood Avenue, Boston, MA 02115, USA.; Broad Institute, Cambridge, MA 02142, USA.<br /><searchLink fieldCode="AU" term="%22Liao+Y%22">Liao Y</searchLink>; Division of Infectious Diseases, Department of Medicine, Brigham and Women's Hospital, 181 Longwood Avenue, Boston, MA 02115, USA.; Broad Institute, Cambridge, MA 02142, USA.<br /><searchLink fieldCode="AU" term="%22Burton+EM%22">Burton EM</searchLink>; Division of Infectious Diseases, Department of Medicine, Brigham and Women's Hospital, 181 Longwood Avenue, Boston, MA 02115, USA.; Broad Institute, Cambridge, MA 02142, USA.<br /><searchLink fieldCode="AU" term="%22Asara+JM%22">Asara JM</searchLink>; Division of Signal Transduction, Beth Israel Deaconess Medical Center and Department of Medicine, Boston, MA 02215, USA.<br /><searchLink fieldCode="AU" term="%22Gewurz+BE%22">Gewurz BE</searchLink>; Division of Infectious Diseases, Department of Medicine, Brigham and Women's Hospital, 181 Longwood Avenue, Boston, MA 02115, USA.; Broad Institute, Cambridge, MA 02142, USA.
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        Value: 10.1101/2025.10.21.683727
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              Text: 2025 Oct 21
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