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WNK kinase regulates plasma membrane levels of the WNT inhibitor RNF43: A WNK-RNF43 circuit regulates WNT signal suppression.

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Title: WNK kinase regulates plasma membrane levels of the WNT inhibitor RNF43: A WNK-RNF43 circuit regulates WNT signal suppression.
Authors: Colozza G; Department of Biology, Unit of Cell and Developmental Biology, University of Pisa, S.S. 12 Abetone e Brennero 4, 56127 Pisa, Italy.; Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna Biocenter Campus (VBC), Dr. Bohr Gasse 3, 1030 Vienna, Austria., Jordens I; Oncode Institute and Centre for Molecular Medicine, University Medical Centre Utrecht, Utrecht, Netherlands., Sosa E; Department of Genetics, Albert Einstein College of Medicine, Bronx, NY, 10461, USA., Ha J; Center for Genome Engineering, Institute for Basic Science, Daejeon 34126, Republic of Korea., Sam Wu SH; Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna Biocenter Campus (VBC), Dr. Bohr Gasse 3, 1030 Vienna, Austria.; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland., Tavernini K; Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna Biocenter Campus (VBC), Dr. Bohr Gasse 3, 1030 Vienna, Austria.; Vienna BioCenter PhD Program, Doctoral School of the University of Vienna and Medical University of Vienna, 1030 Vienna, Austria., Català-Bordes A; Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna Biocenter Campus (VBC), Dr. Bohr Gasse 3, 1030 Vienna, Austria., Farnhammer F; Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna Biocenter Campus (VBC), Dr. Bohr Gasse 3, 1030 Vienna, Austria.; Division of Metabolism and Division of Oncology, University Children's Hospital Zurich and Children's Research Center, University of Zurich, 8032 Zurich, Switzerland., Urbán N; Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna Biocenter Campus (VBC), Dr. Bohr Gasse 3, 1030 Vienna, Austria., Maurice MM; Oncode Institute and Centre for Molecular Medicine, University Medical Centre Utrecht, Utrecht, Netherlands., Koo BK; Center for Genome Engineering, Institute for Basic Science, Daejeon 34126, Republic of Korea.; Graduate School of Stem Cell & Regenerative Biology, KAIST, Daejeon 34141, Republic of Korea.; Department of Life Science, Pohang University of Science and Technology (POSTECH), Pohang 37673, Republic of Korea.; Department of Integrative Biotechnology, Sungkyunkwan University, Suwon, 16419, Republic of Korea.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Oct 08. Date of Electronic Publication: 2025 Oct 08.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: WNK kinase regulates plasma membrane levels of the WNT inhibitor RNF43: A WNK-RNF43 circuit regulates WNT signal suppression.
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  Data: <searchLink fieldCode="AU" term="%22Colozza+G%22">Colozza G</searchLink>; Department of Biology, Unit of Cell and Developmental Biology, University of Pisa, S.S. 12 Abetone e Brennero 4, 56127 Pisa, Italy.; Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna Biocenter Campus (VBC), Dr. Bohr Gasse 3, 1030 Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Jordens+I%22">Jordens I</searchLink>; Oncode Institute and Centre for Molecular Medicine, University Medical Centre Utrecht, Utrecht, Netherlands.<br /><searchLink fieldCode="AU" term="%22Sosa+E%22">Sosa E</searchLink>; Department of Genetics, Albert Einstein College of Medicine, Bronx, NY, 10461, USA.<br /><searchLink fieldCode="AU" term="%22Ha+J%22">Ha J</searchLink>; Center for Genome Engineering, Institute for Basic Science, Daejeon 34126, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Sam+Wu+SH%22">Sam Wu SH</searchLink>; Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna Biocenter Campus (VBC), Dr. Bohr Gasse 3, 1030 Vienna, Austria.; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Tavernini+K%22">Tavernini K</searchLink>; Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna Biocenter Campus (VBC), Dr. Bohr Gasse 3, 1030 Vienna, Austria.; Vienna BioCenter PhD Program, Doctoral School of the University of Vienna and Medical University of Vienna, 1030 Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Català-Bordes+A%22">Català-Bordes A</searchLink>; Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna Biocenter Campus (VBC), Dr. Bohr Gasse 3, 1030 Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Farnhammer+F%22">Farnhammer F</searchLink>; Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna Biocenter Campus (VBC), Dr. Bohr Gasse 3, 1030 Vienna, Austria.; Division of Metabolism and Division of Oncology, University Children's Hospital Zurich and Children's Research Center, University of Zurich, 8032 Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Urbán+N%22">Urbán N</searchLink>; Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna Biocenter Campus (VBC), Dr. Bohr Gasse 3, 1030 Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Maurice+MM%22">Maurice MM</searchLink>; Oncode Institute and Centre for Molecular Medicine, University Medical Centre Utrecht, Utrecht, Netherlands.<br /><searchLink fieldCode="AU" term="%22Koo+BK%22">Koo BK</searchLink>; Center for Genome Engineering, Institute for Basic Science, Daejeon 34126, Republic of Korea.; Graduate School of Stem Cell & Regenerative Biology, KAIST, Daejeon 34141, Republic of Korea.; Department of Life Science, Pohang University of Science and Technology (POSTECH), Pohang 37673, Republic of Korea.; Department of Integrative Biotechnology, Sungkyunkwan University, Suwon, 16419, Republic of Korea.
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  Data: <searchLink fieldCode="JN" term="%22101680187%22">BioRxiv : the preprint server for biology</searchLink> [bioRxiv] 2025 Oct 08. <i>Date of Electronic Publication: </i>2025 Oct 08.
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  Data: <i>Country of Publication: </i>United States <i>NLM ID: </i>101680187 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2692-8205 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226928205%22">26928205 </searchLink><i>NLM ISO Abbreviation: </i>bioRxiv <i>Subsets: </i>PubMed not MEDLINE
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              Text: 2025 Oct 08
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