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mRNA vaccination overcomes hemozoin-mediated impairment of whole parasite vaccine efficacy for malaria.

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Title: mRNA vaccination overcomes hemozoin-mediated impairment of whole parasite vaccine efficacy for malaria.
Authors: Hassert M; Department of Pathology, University of Iowa-Carver College of Medicine, Iowa City, IA, USA., Drewry LL; Department of Pathology, University of Iowa-Carver College of Medicine, Iowa City, IA, USA., Pewe LL; Department of Pathology, University of Iowa-Carver College of Medicine, Iowa City, IA, USA., Hancox LS; Department of Pathology, University of Iowa-Carver College of Medicine, Iowa City, IA, USA., He R; Department of Pharmaceutical Sciences and Experimental Therapeutics, University of Iowa-College of Pharmacy, Iowa City, IA, USA., Arumugam S; Department of Pathology, University of Iowa-Carver College of Medicine, Iowa City, IA, USA.; University of Iowa-Carver College of Medicine Interdisciplinary Graduate Program in Immunology, Iowa City, IA, USA.; University of Iowa Medical Scientist Training Program, Iowa City, IA, USA., Mix MR; Department of Pathology, University of Iowa-Carver College of Medicine, Iowa City, IA, USA.; University of Iowa-Carver College of Medicine Interdisciplinary Graduate Program in Immunology, Iowa City, IA, USA.; University of Iowa Medical Scientist Training Program, Iowa City, IA, USA., Salem AK; Department of Pharmaceutical Sciences and Experimental Therapeutics, University of Iowa-College of Pharmacy, Iowa City, IA, USA., Harty JT; Department of Pathology, University of Iowa-Carver College of Medicine, Iowa City, IA, USA.; University of Iowa-Carver College of Medicine Interdisciplinary Graduate Program in Immunology, Iowa City, IA, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Oct 29. Date of Electronic Publication: 2025 Oct 29.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 41279441
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
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  Data: mRNA vaccination overcomes hemozoin-mediated impairment of whole parasite vaccine efficacy for malaria.
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  Data: <searchLink fieldCode="AU" term="%22Hassert+M%22">Hassert M</searchLink>; Department of Pathology, University of Iowa-Carver College of Medicine, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Drewry+LL%22">Drewry LL</searchLink>; Department of Pathology, University of Iowa-Carver College of Medicine, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Pewe+LL%22">Pewe LL</searchLink>; Department of Pathology, University of Iowa-Carver College of Medicine, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Hancox+LS%22">Hancox LS</searchLink>; Department of Pathology, University of Iowa-Carver College of Medicine, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22He+R%22">He R</searchLink>; Department of Pharmaceutical Sciences and Experimental Therapeutics, University of Iowa-College of Pharmacy, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Arumugam+S%22">Arumugam S</searchLink>; Department of Pathology, University of Iowa-Carver College of Medicine, Iowa City, IA, USA.; University of Iowa-Carver College of Medicine Interdisciplinary Graduate Program in Immunology, Iowa City, IA, USA.; University of Iowa Medical Scientist Training Program, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Mix+MR%22">Mix MR</searchLink>; Department of Pathology, University of Iowa-Carver College of Medicine, Iowa City, IA, USA.; University of Iowa-Carver College of Medicine Interdisciplinary Graduate Program in Immunology, Iowa City, IA, USA.; University of Iowa Medical Scientist Training Program, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Salem+AK%22">Salem AK</searchLink>; Department of Pharmaceutical Sciences and Experimental Therapeutics, University of Iowa-College of Pharmacy, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Harty+JT%22">Harty JT</searchLink>; Department of Pathology, University of Iowa-Carver College of Medicine, Iowa City, IA, USA.; University of Iowa-Carver College of Medicine Interdisciplinary Graduate Program in Immunology, Iowa City, IA, USA.
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  Data: <searchLink fieldCode="JN" term="%22101680187%22">BioRxiv : the preprint server for biology</searchLink> [bioRxiv] 2025 Oct 29. <i>Date of Electronic Publication: </i>2025 Oct 29.
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  Data: <i>Country of Publication: </i>United States <i>NLM ID: </i>101680187 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2692-8205 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226928205%22">26928205 </searchLink><i>NLM ISO Abbreviation: </i>bioRxiv <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.1101/2025.10.29.685344
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      – Code: eng
        Text: English
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      – TitleFull: mRNA vaccination overcomes hemozoin-mediated impairment of whole parasite vaccine efficacy for malaria.
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              Text: 2025 Oct 29
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