Intraspecific sequence variation and complete genomes refine the identification of rapidly evolved regions in humans.
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| Title: | Intraspecific sequence variation and complete genomes refine the identification of rapidly evolved regions in humans. |
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| Authors: | Luo Y; Department of Molecular Genetics and Microbiology, Duke University, Durham, NC 27710, USA.; Department of Cell Biology, Duke University, Durham, NC 27710, USA.; University Program in Genetics and Genomics, Duke University, Durham, NC 27710, USA.; These authors contributed equally to this work., Mangan RJ; Computer Science and Artificial Intelligence Lab, Massachusetts Institute of Technology, 32 Vassar St, Cambridge, MA 02139, USA.; The Broad Institute of MIT and Harvard, 415 Main Street, Cambridge, MA 02142, USA.; Genetics Training Program, Harvard Medical School, 25 Shattuck St, Boston MA, 02115, USA.; These authors contributed equally to this work., Weaver S; Department of Molecular Genetics and Microbiology, Duke University, Durham, NC 27710, USA.; Department of Cell Biology, Duke University, Durham, NC 27710, USA.; University Program in Genetics and Genomics, Duke University, Durham, NC 27710, USA., Zhao SA; Computer Science and Artificial Intelligence Lab, Massachusetts Institute of Technology, 32 Vassar St, Cambridge, MA 02139, USA.; The Broad Institute of MIT and Harvard, 415 Main Street, Cambridge, MA 02142, USA., Mosti F; Department of Molecular Genetics and Microbiology, Duke University, Durham, NC 27710, USA.; Department of Cell Biology, Duke University, Durham, NC 27710, USA.; Department of Neurobiology, Duke University Medical Center, Durham, NC 27710, USA., Thomas MC; Division of Cardiology, Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA., Karra R; Division of Cardiology, Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA.; Department of Pathology, Duke University Medical Center, Durham, NC 27710, USA., Silver DL; Department of Molecular Genetics and Microbiology, Duke University, Durham, NC 27710, USA.; Department of Cell Biology, Duke University, Durham, NC 27710, USA.; Duke Institute for Brain Sciences and Duke Regeneration Center, Duke University Medical Center, Durham, NC 27710, USA.; Department of Neurobiology, Duke University Medical Center, Durham, NC 27710, USA., Kellis M; Computer Science and Artificial Intelligence Lab, Massachusetts Institute of Technology, 32 Vassar St, Cambridge, MA 02139, USA.; The Broad Institute of MIT and Harvard, 415 Main Street, Cambridge, MA 02142, USA., Lowe CB; Department of Molecular Genetics and Microbiology, Duke University, Durham, NC 27710, USA.; Department of Cell Biology, Duke University, Durham, NC 27710, USA.; University Program in Genetics and Genomics, Duke University, Durham, NC 27710, USA.; Lead contact. |
| Source: | BioRxiv : the preprint server for biology [bioRxiv] 2025 Oct 21. Date of Electronic Publication: 2025 Oct 21. |
| Publication Type: | Journal Article; Preprint |
| Journal Info: | Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41279559 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Intraspecific sequence variation and complete genomes refine the identification of rapidly evolved regions in humans. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Luo+Y%22">Luo Y</searchLink>; Department of Molecular Genetics and Microbiology, Duke University, Durham, NC 27710, USA.; Department of Cell Biology, Duke University, Durham, NC 27710, USA.; University Program in Genetics and Genomics, Duke University, Durham, NC 27710, USA.; These authors contributed equally to this work.<br /><searchLink fieldCode="AU" term="%22Mangan+RJ%22">Mangan RJ</searchLink>; Computer Science and Artificial Intelligence Lab, Massachusetts Institute of Technology, 32 Vassar St, Cambridge, MA 02139, USA.; The Broad Institute of MIT and Harvard, 415 Main Street, Cambridge, MA 02142, USA.; Genetics Training Program, Harvard Medical School, 25 Shattuck St, Boston MA, 02115, USA.; These authors contributed equally to this work.<br /><searchLink fieldCode="AU" term="%22Weaver+S%22">Weaver S</searchLink>; Department of Molecular Genetics and Microbiology, Duke University, Durham, NC 27710, USA.; Department of Cell Biology, Duke University, Durham, NC 27710, USA.; University Program in Genetics and Genomics, Duke University, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Zhao+SA%22">Zhao SA</searchLink>; Computer Science and Artificial Intelligence Lab, Massachusetts Institute of Technology, 32 Vassar St, Cambridge, MA 02139, USA.; The Broad Institute of MIT and Harvard, 415 Main Street, Cambridge, MA 02142, USA.<br /><searchLink fieldCode="AU" term="%22Mosti+F%22">Mosti F</searchLink>; Department of Molecular Genetics and Microbiology, Duke University, Durham, NC 27710, USA.; Department of Cell Biology, Duke University, Durham, NC 27710, USA.; Department of Neurobiology, Duke University Medical Center, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Thomas+MC%22">Thomas MC</searchLink>; Division of Cardiology, Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Karra+R%22">Karra R</searchLink>; Division of Cardiology, Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA.; Department of Pathology, Duke University Medical Center, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Silver+DL%22">Silver DL</searchLink>; Department of Molecular Genetics and Microbiology, Duke University, Durham, NC 27710, USA.; Department of Cell Biology, Duke University, Durham, NC 27710, USA.; Duke Institute for Brain Sciences and Duke Regeneration Center, Duke University Medical Center, Durham, NC 27710, USA.; Department of Neurobiology, Duke University Medical Center, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Kellis+M%22">Kellis M</searchLink>; Computer Science and Artificial Intelligence Lab, Massachusetts Institute of Technology, 32 Vassar St, Cambridge, MA 02139, USA.; The Broad Institute of MIT and Harvard, 415 Main Street, Cambridge, MA 02142, USA.<br /><searchLink fieldCode="AU" term="%22Lowe+CB%22">Lowe CB</searchLink>; Department of Molecular Genetics and Microbiology, Duke University, Durham, NC 27710, USA.; Department of Cell Biology, Duke University, Durham, NC 27710, USA.; University Program in Genetics and Genomics, Duke University, Durham, NC 27710, USA.; Lead contact. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101680187%22">BioRxiv : the preprint server for biology</searchLink> [bioRxiv] 2025 Oct 21. <i>Date of Electronic Publication: </i>2025 Oct 21. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Preprint – Name: TitleSource Label: Journal Info Group: Src Data: <i>Country of Publication: </i>United States <i>NLM ID: </i>101680187 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2692-8205 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226928205%22">26928205 </searchLink><i>NLM ISO Abbreviation: </i>bioRxiv <i>Subsets: </i>PubMed not MEDLINE |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1101/2025.10.20.683446 Languages: – Code: eng Text: English Titles: – TitleFull: Intraspecific sequence variation and complete genomes refine the identification of rapidly evolved regions in humans. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Luo Y – PersonEntity: Name: NameFull: Mangan RJ – PersonEntity: Name: NameFull: Weaver S – PersonEntity: Name: NameFull: Zhao SA – PersonEntity: Name: NameFull: Mosti F – PersonEntity: Name: NameFull: Thomas MC – PersonEntity: Name: NameFull: Karra R – PersonEntity: Name: NameFull: Silver DL – PersonEntity: Name: NameFull: Kellis M – PersonEntity: Name: NameFull: Lowe CB IsPartOfRelationships: – BibEntity: Dates: – D: 21 M: 10 Text: 2025 Oct 21 Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 2692-8205 Titles: – TitleFull: BioRxiv : the preprint server for biology Type: main |
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