The scaffold protein PRR14L links the PP2A-TACC3 axis to mitotic fidelity and sensitivity to MPS1 inhibition.
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| Title: | The scaffold protein PRR14L links the PP2A-TACC3 axis to mitotic fidelity and sensitivity to MPS1 inhibition. |
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| Authors: | Liu AZ; Department of Cell Biology, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.; Mechanobiology Institute, National University of Singapore, Singapore 117411, Singapore., Narkar A; Department of Cell Biology, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA., Li K; Mechanobiology Institute, National University of Singapore, Singapore 117411, Singapore., Bertomeu T; The ChemoGenix CRISPR screening facility of the Institute for Research in Immunology and Cancer, University of Montreal, 2950 Chemin de Polytechnique, Montréal, QC H3T 1J4, Canada., Johnson BA; Department of Cell Biology, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA., Coulombe-Huntington J; Department of Bioengineering, McGill University, Montreal, QC H3A 0E9, Canada., Dong Y; Department of Cell Biology, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA., Zhu J; Mechanobiology Institute, National University of Singapore, Singapore 117411, Singapore., Tyers M; Department of Molecular Genetics, University of Toronto; Toronto, Ontario M5S 1A8, Canada.; Program in Molecular Medicine, Peter Gilgan Centre for Research and Learning, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada., Li R; Department of Cell Biology, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.; Mechanobiology Institute, National University of Singapore, Singapore 117411, Singapore.; Department of Biological Sciences, National University of Singapore, Singapore 117558, Singapore. |
| Source: | BioRxiv : the preprint server for biology [bioRxiv] 2025 Dec 29. Date of Electronic Publication: 2025 Dec 29. |
| Publication Type: | Journal Article; Preprint |
| Journal Info: | Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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