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Divergent T Cell Phenotypes Define Pediatric Crohn's Disease and Ulcerative Colitis.

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Title: Divergent T Cell Phenotypes Define Pediatric Crohn's Disease and Ulcerative Colitis.
Authors: Nettey L; Program in Immunology, Harvard Medical School, Boston, MA 02115, USA.; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA 02142, USA.; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Zheng HB; Division of Gastroenterology and Hepatology, Seattle Children's Hospital and University of Washington, Seattle, WA 98105, USA., Devlin JC; Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., Horowitz JE; Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., Rosenbaum S; Division of Gastroenterology, Hepatology, and Nutrition, Boston Children's Hospital, Boston, MA 02115, USA., Fiaschi N; Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., Lim WK; Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., Kimler K; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA 02142, USA.; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Division of Gastroenterology, Hepatology, and Nutrition, Boston Children's Hospital, Boston, MA 02115, USA.; Division of Pediatric Hematology/Oncology, Boston Children's Hospital, Boston, MA 02115, USA., Adler C; Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., Lee A; Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., Ni M; Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., Wei Y; Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., Ehmann PJ; Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., McCarthy SE; Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., Ferreira MAR; Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., Galbavy W; Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., Stahl E; Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., Haxhinasto S; Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., Coetzee S; Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., Yabe Y; Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., Dobosz M; Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., Keskula P; Division of Pediatric Hematology/Oncology, Boston Children's Hospital, Boston, MA 02115, USA., Zavistaski J; Division of Pediatric Hematology/Oncology, Boston Children's Hospital, Boston, MA 02115, USA., Albanese A; Division of Pediatric Hematology/Oncology, Boston Children's Hospital, Boston, MA 02115, USA., Steier Z; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA 02142, USA.; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., de Sousa Casal J; Program in Immunology, Harvard Medical School, Boston, MA 02115, USA.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Division of Gastroenterology, Hepatology, and Nutrition, Boston Children's Hospital, Boston, MA 02115, USA., Niederlova V; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Division of Gastroenterology, Hepatology, and Nutrition, Boston Children's Hospital, Boston, MA 02115, USA.; Laboratory of Adaptive Immunity, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic., Ambartsumyan L; Division of Gastroenterology and Hepatology, Seattle Children's Hospital and University of Washington, Seattle, WA 98105, USA., Wahbeh G; Division of Gastroenterology and Hepatology, Seattle Children's Hospital and University of Washington, Seattle, WA 98105, USA., Suskind DL; Division of Gastroenterology and Hepatology, Seattle Children's Hospital and University of Washington, Seattle, WA 98105, USA., Mitsialis V; Division of Gastroenterology, Hepatology, and Nutrition, Boston Children's Hospital, Boston, MA 02115, USA.; Brigham and Women's Hospital Department of Medicine, Division of Gastroenterology, Hepatology, and Endoscopy, Boston, MA 02115, USA., Hamon S; Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., Carpenter SM; Division of Infectious Diseases and HIV Medicine, Department of Medicine, University Hospitals, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA., Hamilton JD; Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., Shalek AK; Program in Immunology, Harvard Medical School, Boston, MA 02115, USA.; Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA 02142, USA.; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Harvard Medical School, Boston, MA 02115, USA.; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Snapper SB; Division of Gastroenterology, Hepatology, and Nutrition, Boston Children's Hospital, Boston, MA 02115, USA.; Brigham and Women's Hospital Department of Medicine, Division of Gastroenterology, Hepatology, and Endoscopy, Boston, MA 02115, USA.; Harvard Medical School, Boston, MA 02115, USA., Sleeman MA; Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., Kalliolias GD; Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., Hooper AT; Regeneron Pharmaceuticals Inc., Tarrytown, NY 10591, USA., Ordovas-Montanes J; Program in Immunology, Harvard Medical School, Boston, MA 02115, USA.; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Division of Gastroenterology, Hepatology, and Nutrition, Boston Children's Hospital, Boston, MA 02115, USA.; Harvard Stem Cell Institute, Cambridge, MA 02138, USA., Kean LS; Division of Pediatric Hematology/Oncology, Boston Children's Hospital, Boston, MA 02115, USA.; Dana Farber Cancer Institute, Boston, MA 02215, USA.
Source: MedRxiv : the preprint server for health sciences [medRxiv] 2025 Oct 17. Date of Electronic Publication: 2025 Oct 17.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101767986 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: medRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
FullText Text:
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An: 41282815
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PubType: Academic Journal
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