View in EDS

Helixer: ab initio prediction of primary eukaryotic gene models combining deep learning and a hidden Markov model.

Saved in:
Bibliographic Details
Title: Helixer: ab initio prediction of primary eukaryotic gene models combining deep learning and a hidden Markov model.
Authors: Holst F; Institute of Plant Biochemistry, Heinrich Heine University, Düsseldorf, Germany., Bolger AM; IBG-4 Bioinformatics, Forschungszentrum Jülich, Jülich, Germany., Kindel F; Institute of Plant Biochemistry, Heinrich Heine University, Düsseldorf, Germany.; IBG-4 Bioinformatics, Forschungszentrum Jülich, Jülich, Germany., Günther C; Institute of Plant Biochemistry, Heinrich Heine University, Düsseldorf, Germany., Maß J; Institute of Quantitative and Theoretical Biology, Heinrich Heine University, Düsseldorf, Germany., Triesch S; Institute of Plant Biochemistry, Heinrich Heine University, Düsseldorf, Germany.; Cluster of Excellence on Plant Sciences, Heinrich Heine University, Düsseldorf, Germany., Kiel N; Institute of Plant Biochemistry, Heinrich Heine University, Düsseldorf, Germany.; Cluster of Excellence on Plant Sciences, Heinrich Heine University, Düsseldorf, Germany., Saadat N; Institute of Quantitative and Theoretical Biology, Heinrich Heine University, Düsseldorf, Germany.; Cluster of Excellence on Plant Sciences, Heinrich Heine University, Düsseldorf, Germany., Ebenhöh O; Institute of Quantitative and Theoretical Biology, Heinrich Heine University, Düsseldorf, Germany.; Cluster of Excellence on Plant Sciences, Heinrich Heine University, Düsseldorf, Germany., Usadel B; IBG-4 Bioinformatics, Forschungszentrum Jülich, Jülich, Germany.; Cluster of Excellence on Plant Sciences, Heinrich Heine University, Düsseldorf, Germany.; Institute for Biological Data Science, Heinrich Heine University, Düsseldorf, Germany., Schwacke R; IBG-4 Bioinformatics, Forschungszentrum Jülich, Jülich, Germany., Weber APM; Institute of Plant Biochemistry, Heinrich Heine University, Düsseldorf, Germany.; Cluster of Excellence on Plant Sciences, Heinrich Heine University, Düsseldorf, Germany., Bolger ME; IBG-4 Bioinformatics, Forschungszentrum Jülich, Jülich, Germany. m.bolger@fz-juelich.de., Denton AK; Institute of Plant Biochemistry, Heinrich Heine University, Düsseldorf, Germany.; Cluster of Excellence on Plant Sciences, Heinrich Heine University, Düsseldorf, Germany.; Recursion, Valence Labs, Montreal, Quebec, Canada.
Source: Nature methods [Nat Methods] 2026 Apr; Vol. 23 (4), pp. 732-739. Date of Electronic Publication: 2025 Nov 24.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101215604 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1548-7105 (Electronic) Linking ISSN: 15487091 NLM ISO Abbreviation: Nat Methods Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 41286201
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Helixer: ab initio prediction of primary eukaryotic gene models combining deep learning and a hidden Markov model.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Holst+F%22">Holst F</searchLink>; Institute of Plant Biochemistry, Heinrich Heine University, Düsseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22Bolger+AM%22">Bolger AM</searchLink>; IBG-4 Bioinformatics, Forschungszentrum Jülich, Jülich, Germany.<br /><searchLink fieldCode="AU" term="%22Kindel+F%22">Kindel F</searchLink>; Institute of Plant Biochemistry, Heinrich Heine University, Düsseldorf, Germany.; IBG-4 Bioinformatics, Forschungszentrum Jülich, Jülich, Germany.<br /><searchLink fieldCode="AU" term="%22Günther+C%22">Günther C</searchLink>; Institute of Plant Biochemistry, Heinrich Heine University, Düsseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22Maß+J%22">Maß J</searchLink>; Institute of Quantitative and Theoretical Biology, Heinrich Heine University, Düsseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22Triesch+S%22">Triesch S</searchLink>; Institute of Plant Biochemistry, Heinrich Heine University, Düsseldorf, Germany.; Cluster of Excellence on Plant Sciences, Heinrich Heine University, Düsseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22Kiel+N%22">Kiel N</searchLink>; Institute of Plant Biochemistry, Heinrich Heine University, Düsseldorf, Germany.; Cluster of Excellence on Plant Sciences, Heinrich Heine University, Düsseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22Saadat+N%22">Saadat N</searchLink>; Institute of Quantitative and Theoretical Biology, Heinrich Heine University, Düsseldorf, Germany.; Cluster of Excellence on Plant Sciences, Heinrich Heine University, Düsseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22Ebenhöh+O%22">Ebenhöh O</searchLink>; Institute of Quantitative and Theoretical Biology, Heinrich Heine University, Düsseldorf, Germany.; Cluster of Excellence on Plant Sciences, Heinrich Heine University, Düsseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22Usadel+B%22">Usadel B</searchLink>; IBG-4 Bioinformatics, Forschungszentrum Jülich, Jülich, Germany.; Cluster of Excellence on Plant Sciences, Heinrich Heine University, Düsseldorf, Germany.; Institute for Biological Data Science, Heinrich Heine University, Düsseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22Schwacke+R%22">Schwacke R</searchLink>; IBG-4 Bioinformatics, Forschungszentrum Jülich, Jülich, Germany.<br /><searchLink fieldCode="AU" term="%22Weber+APM%22">Weber APM</searchLink>; Institute of Plant Biochemistry, Heinrich Heine University, Düsseldorf, Germany.; Cluster of Excellence on Plant Sciences, Heinrich Heine University, Düsseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22Bolger+ME%22">Bolger ME</searchLink>; IBG-4 Bioinformatics, Forschungszentrum Jülich, Jülich, Germany. m.bolger@fz-juelich.de.<br /><searchLink fieldCode="AU" term="%22Denton+AK%22">Denton AK</searchLink>; Institute of Plant Biochemistry, Heinrich Heine University, Düsseldorf, Germany.; Cluster of Excellence on Plant Sciences, Heinrich Heine University, Düsseldorf, Germany.; Recursion, Valence Labs, Montreal, Quebec, Canada.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101215604%22">Nature methods</searchLink> [Nat Methods] 2026 Apr; Vol. 23 (4), pp. 732-739. <i>Date of Electronic Publication: </i>2025 Nov 24.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. Group </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101215604 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1548-7105 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215487091%22">15487091 </searchLink><i>NLM ISO Abbreviation: </i>Nat Methods <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41286201
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1038/s41592-025-02939-1
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 732
    Titles:
      – TitleFull: Helixer: ab initio prediction of primary eukaryotic gene models combining deep learning and a hidden Markov model.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Holst F
      – PersonEntity:
          Name:
            NameFull: Bolger AM
      – PersonEntity:
          Name:
            NameFull: Kindel F
      – PersonEntity:
          Name:
            NameFull: Günther C
      – PersonEntity:
          Name:
            NameFull: Maß J
      – PersonEntity:
          Name:
            NameFull: Triesch S
      – PersonEntity:
          Name:
            NameFull: Kiel N
      – PersonEntity:
          Name:
            NameFull: Saadat N
      – PersonEntity:
          Name:
            NameFull: Ebenhöh O
      – PersonEntity:
          Name:
            NameFull: Usadel B
      – PersonEntity:
          Name:
            NameFull: Schwacke R
      – PersonEntity:
          Name:
            NameFull: Weber APM
      – PersonEntity:
          Name:
            NameFull: Bolger ME
      – PersonEntity:
          Name:
            NameFull: Denton AK
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 04
              Text: 2026 Apr
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1548-7105
          Numbering:
            – Type: volume
              Value: 23
            – Type: issue
              Value: 4
          Titles:
            – TitleFull: Nature methods
              Type: main
ResultId 1