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The Histidine Kinase VraS Interacts with Vancomycin and Penicillins Through its Membrane-Anchored N-terminal Domain.

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Title: The Histidine Kinase VraS Interacts with Vancomycin and Penicillins Through its Membrane-Anchored N-terminal Domain.
Authors: Antinori MB; Instituto de Biología Molecular y Celular de Rosario (IBR), CONICET-UNR, 27 de Febrero 210 bis, Rosario, 2000, Argentina., Peralta MD; Instituto de Biología Molecular y Celular de Rosario (IBR), CONICET-UNR, 27 de Febrero 210 bis, Rosario, 2000, Argentina., Suárez IP; Instituto de Biología Molecular y Celular de Rosario (IBR), CONICET-UNR, 27 de Febrero 210 bis, Rosario, 2000, Argentina., Sychantha D; M.G. DeGroote Institute for Infectious Disease Research, McMaster University, 1280 Main St W, Hamilton, ON, L8S 4L8, Canada.; Department of Biochemistry and Biomedical Sciences, McMaster University, 1280 Main St W, Hamilton, ON, L8S 4L8, Canada., Koteva K; M.G. DeGroote Institute for Infectious Disease Research, McMaster University, 1280 Main St W, Hamilton, ON, L8S 4L8, Canada.; Department of Biochemistry and Biomedical Sciences, McMaster University, 1280 Main St W, Hamilton, ON, L8S 4L8, Canada., Méndez L; Instituto de Química Rosario (IQUIR), CONICET-UNR, 27 de Febrero 210 bis, Rosario, 2000, Argentina., Testero SA; Instituto de Química Rosario (IQUIR), CONICET-UNR, 27 de Febrero 210 bis, Rosario, 2000, Argentina.; Área Química Orgánica, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario (UNR), Suipacha 570, Rosario, 2000, Argentina., Wright GD; M.G. DeGroote Institute for Infectious Disease Research, McMaster University, 1280 Main St W, Hamilton, ON, L8S 4L8, Canada.; Department of Biochemistry and Biomedical Sciences, McMaster University, 1280 Main St W, Hamilton, ON, L8S 4L8, Canada., Llarrull LI; Instituto de Biología Molecular y Celular de Rosario (IBR), CONICET-UNR, 27 de Febrero 210 bis, Rosario, 2000, Argentina.; Área Biofísica, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario (UNR), Suipacha 570, Rosario, 2000, Argentina.
Source: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2026 Jan 16; Vol. 65 (3), pp. e16608. Date of Electronic Publication: 2025 Nov 24.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 0370543 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-3773 (Electronic) Linking ISSN: 14337851 NLM ISO Abbreviation: Angew Chem Int Ed Engl Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: The Histidine Kinase VraS Interacts with Vancomycin and Penicillins Through its Membrane-Anchored N-terminal Domain.
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  Data: <searchLink fieldCode="AU" term="%22Antinori+MB%22">Antinori MB</searchLink>; Instituto de Biología Molecular y Celular de Rosario (IBR), CONICET-UNR, 27 de Febrero 210 bis, Rosario, 2000, Argentina.<br /><searchLink fieldCode="AU" term="%22Peralta+MD%22">Peralta MD</searchLink>; Instituto de Biología Molecular y Celular de Rosario (IBR), CONICET-UNR, 27 de Febrero 210 bis, Rosario, 2000, Argentina.<br /><searchLink fieldCode="AU" term="%22Suárez+IP%22">Suárez IP</searchLink>; Instituto de Biología Molecular y Celular de Rosario (IBR), CONICET-UNR, 27 de Febrero 210 bis, Rosario, 2000, Argentina.<br /><searchLink fieldCode="AU" term="%22Sychantha+D%22">Sychantha D</searchLink>; M.G. DeGroote Institute for Infectious Disease Research, McMaster University, 1280 Main St W, Hamilton, ON, L8S 4L8, Canada.; Department of Biochemistry and Biomedical Sciences, McMaster University, 1280 Main St W, Hamilton, ON, L8S 4L8, Canada.<br /><searchLink fieldCode="AU" term="%22Koteva+K%22">Koteva K</searchLink>; M.G. DeGroote Institute for Infectious Disease Research, McMaster University, 1280 Main St W, Hamilton, ON, L8S 4L8, Canada.; Department of Biochemistry and Biomedical Sciences, McMaster University, 1280 Main St W, Hamilton, ON, L8S 4L8, Canada.<br /><searchLink fieldCode="AU" term="%22Méndez+L%22">Méndez L</searchLink>; Instituto de Química Rosario (IQUIR), CONICET-UNR, 27 de Febrero 210 bis, Rosario, 2000, Argentina.<br /><searchLink fieldCode="AU" term="%22Testero+SA%22">Testero SA</searchLink>; Instituto de Química Rosario (IQUIR), CONICET-UNR, 27 de Febrero 210 bis, Rosario, 2000, Argentina.; Área Química Orgánica, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario (UNR), Suipacha 570, Rosario, 2000, Argentina.<br /><searchLink fieldCode="AU" term="%22Wright+GD%22">Wright GD</searchLink>; M.G. DeGroote Institute for Infectious Disease Research, McMaster University, 1280 Main St W, Hamilton, ON, L8S 4L8, Canada.; Department of Biochemistry and Biomedical Sciences, McMaster University, 1280 Main St W, Hamilton, ON, L8S 4L8, Canada.<br /><searchLink fieldCode="AU" term="%22Llarrull+LI%22">Llarrull LI</searchLink>; Instituto de Biología Molecular y Celular de Rosario (IBR), CONICET-UNR, 27 de Febrero 210 bis, Rosario, 2000, Argentina.; Área Biofísica, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario (UNR), Suipacha 570, Rosario, 2000, Argentina.
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  Data: <searchLink fieldCode="JN" term="%220370543%22">Angewandte Chemie (International ed. in English)</searchLink> [Angew Chem Int Ed Engl] 2026 Jan 16; Vol. 65 (3), pp. e16608. <i>Date of Electronic Publication: </i>2025 Nov 24.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley-VCH%22">Wiley-VCH </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>0370543 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1521-3773 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214337851%22">14337851 </searchLink><i>NLM ISO Abbreviation: </i>Angew Chem Int Ed Engl <i>Subsets: </i>MEDLINE
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              Text: 2026 Jan 16
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