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PTEN-deficient, chromosomal instability colorectal cancer is hypersensitive to STAT3 inhibition.

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Title: PTEN-deficient, chromosomal instability colorectal cancer is hypersensitive to STAT3 inhibition.
Authors: Ren G; Cancer Centre, Faculty of Health Sciences, University of Macau, Taipa, Macau SAR, China.; Institute of Cancer Research, Shenzhen Bay Laboratory, Shenzhen 518132, China., Pu Y; Cancer Centre, Faculty of Health Sciences, University of Macau, Taipa, Macau SAR, China., Zhang X; Cancer Centre, Faculty of Health Sciences, University of Macau, Taipa, Macau SAR, China., Chen J; Cancer Centre, Faculty of Health Sciences, University of Macau, Taipa, Macau SAR, China.; Laboratory Animal Center, Guangzhou Medical University, Guangzhou, China., Yang EJ; Cancer Centre, Faculty of Health Sciences, University of Macau, Taipa, Macau SAR, China., Tao S; Cancer Centre, Faculty of Health Sciences, University of Macau, Taipa, Macau SAR, China.; Institute of Cancer Research, Shenzhen Bay Laboratory, Shenzhen 518132, China., Chen LJ; Cancer Centre, Faculty of Health Sciences, University of Macau, Taipa, Macau SAR, China., Zhu W; Kiang Wu Hospital, Macau SAR, China., Chan KL; Kiang Wu Hospital, Macau SAR, China., Luo G; Kiang Wu Hospital, Macau SAR, China., Deng C; Cancer Centre, Faculty of Health Sciences, University of Macau, Taipa, Macau SAR, China.; MOE Frontiers Science Center for Precision Oncology, University of Macau, Taipa, Macau SAR, China., Shim JS; Cancer Centre, Faculty of Health Sciences, University of Macau, Taipa, Macau SAR, China.; MOE Frontiers Science Center for Precision Oncology, University of Macau, Taipa, Macau SAR, China.
Source: International journal of biological sciences [Int J Biol Sci] 2025 Oct 20; Vol. 21 (15), pp. 6633-6648. Date of Electronic Publication: 2025 Oct 20 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Ivyspring International Country of Publication: Australia NLM ID: 101235568 Publication Model: eCollection Cited Medium: Internet ISSN: 1449-2288 (Electronic) Linking ISSN: 14492288 NLM ISO Abbreviation: Int J Biol Sci Subsets: MEDLINE
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  Data: PTEN-deficient, chromosomal instability colorectal cancer is hypersensitive to STAT3 inhibition.
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  Data: <searchLink fieldCode="AU" term="%22Ren+G%22">Ren G</searchLink>; Cancer Centre, Faculty of Health Sciences, University of Macau, Taipa, Macau SAR, China.; Institute of Cancer Research, Shenzhen Bay Laboratory, Shenzhen 518132, China.<br /><searchLink fieldCode="AU" term="%22Pu+Y%22">Pu Y</searchLink>; Cancer Centre, Faculty of Health Sciences, University of Macau, Taipa, Macau SAR, China.<br /><searchLink fieldCode="AU" term="%22Zhang+X%22">Zhang X</searchLink>; Cancer Centre, Faculty of Health Sciences, University of Macau, Taipa, Macau SAR, China.<br /><searchLink fieldCode="AU" term="%22Chen+J%22">Chen J</searchLink>; Cancer Centre, Faculty of Health Sciences, University of Macau, Taipa, Macau SAR, China.; Laboratory Animal Center, Guangzhou Medical University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Yang+EJ%22">Yang EJ</searchLink>; Cancer Centre, Faculty of Health Sciences, University of Macau, Taipa, Macau SAR, China.<br /><searchLink fieldCode="AU" term="%22Tao+S%22">Tao S</searchLink>; Cancer Centre, Faculty of Health Sciences, University of Macau, Taipa, Macau SAR, China.; Institute of Cancer Research, Shenzhen Bay Laboratory, Shenzhen 518132, China.<br /><searchLink fieldCode="AU" term="%22Chen+LJ%22">Chen LJ</searchLink>; Cancer Centre, Faculty of Health Sciences, University of Macau, Taipa, Macau SAR, China.<br /><searchLink fieldCode="AU" term="%22Zhu+W%22">Zhu W</searchLink>; Kiang Wu Hospital, Macau SAR, China.<br /><searchLink fieldCode="AU" term="%22Chan+KL%22">Chan KL</searchLink>; Kiang Wu Hospital, Macau SAR, China.<br /><searchLink fieldCode="AU" term="%22Luo+G%22">Luo G</searchLink>; Kiang Wu Hospital, Macau SAR, China.<br /><searchLink fieldCode="AU" term="%22Deng+C%22">Deng C</searchLink>; Cancer Centre, Faculty of Health Sciences, University of Macau, Taipa, Macau SAR, China.; MOE Frontiers Science Center for Precision Oncology, University of Macau, Taipa, Macau SAR, China.<br /><searchLink fieldCode="AU" term="%22Shim+JS%22">Shim JS</searchLink>; Cancer Centre, Faculty of Health Sciences, University of Macau, Taipa, Macau SAR, China.; MOE Frontiers Science Center for Precision Oncology, University of Macau, Taipa, Macau SAR, China.
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  Data: <searchLink fieldCode="JN" term="%22101235568%22">International journal of biological sciences</searchLink> [Int J Biol Sci] 2025 Oct 20; Vol. 21 (15), pp. 6633-6648. <i>Date of Electronic Publication: </i>2025 Oct 20 (<i>Print Publication: </i>2025).
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