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Isolation-free manufacturing of lipophilic API-ionic liquids (API-ILs) and their solidified products for oral solid dosage formulations.

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Title: Isolation-free manufacturing of lipophilic API-ionic liquids (API-ILs) and their solidified products for oral solid dosage formulations.
Authors: Tsolaki E; School of Chemical and Bioprocess Engineering, University College Dublin, Dublin 4, Ireland; SSPC, The Research Ireland Centre for Pharmaceuticals, School of Chemical and Bioprocess Engineering, University College Dublin, Dublin 4, Ireland; EPSRC-SFI Centre for Doctoral Training in Transformative Pharmaceutical Technologies, Ireland., Mamo E; School of Chemical and Bioprocess Engineering, University College Dublin, Dublin 4, Ireland; SSPC, The Research Ireland Centre for Pharmaceuticals, School of Chemical and Bioprocess Engineering, University College Dublin, Dublin 4, Ireland., Rodriguez RL; School of Chemical and Bioprocess Engineering, University College Dublin, Dublin 4, Ireland., De Hert SC; School of Chemical and Bioprocess Engineering, University College Dublin, Dublin 4, Ireland., Healy AM; EPSRC-SFI Centre for Doctoral Training in Transformative Pharmaceutical Technologies, Ireland; SSPC, The Research Ireland Centre for Pharmaceuticals, School of Pharmacy and Pharmaceutical Sciences, Panoz Institute, Trinity College Dublin, Dublin 2, Ireland., Ferguson S; School of Chemical and Bioprocess Engineering, University College Dublin, Dublin 4, Ireland; SSPC, The Research Ireland Centre for Pharmaceuticals, School of Chemical and Bioprocess Engineering, University College Dublin, Dublin 4, Ireland; EPSRC-SFI Centre for Doctoral Training in Transformative Pharmaceutical Technologies, Ireland; National Institute for Bioprocessing Research and Training, 24 Foster's Ave, Belfield, Blackrock, Co. Dublin A94 X099, Ireland. Electronic address: steven.ferguson@ucd.ie.
Source: International journal of pharmaceutics [Int J Pharm] 2026 Jan 05; Vol. 687, pp. 126428. Date of Electronic Publication: 2025 Nov 23.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7804127 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3476 (Electronic) Linking ISSN: 03785173 NLM ISO Abbreviation: Int J Pharm Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Isolation-free manufacturing of lipophilic API-ionic liquids (API-ILs) and their solidified products for oral solid dosage formulations.
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  Data: <searchLink fieldCode="AU" term="%22Tsolaki+E%22">Tsolaki E</searchLink>; School of Chemical and Bioprocess Engineering, University College Dublin, Dublin 4, Ireland; SSPC, The Research Ireland Centre for Pharmaceuticals, School of Chemical and Bioprocess Engineering, University College Dublin, Dublin 4, Ireland; EPSRC-SFI Centre for Doctoral Training in Transformative Pharmaceutical Technologies, Ireland.<br /><searchLink fieldCode="AU" term="%22Mamo+E%22">Mamo E</searchLink>; School of Chemical and Bioprocess Engineering, University College Dublin, Dublin 4, Ireland; SSPC, The Research Ireland Centre for Pharmaceuticals, School of Chemical and Bioprocess Engineering, University College Dublin, Dublin 4, Ireland.<br /><searchLink fieldCode="AU" term="%22Rodriguez+RL%22">Rodriguez RL</searchLink>; School of Chemical and Bioprocess Engineering, University College Dublin, Dublin 4, Ireland.<br /><searchLink fieldCode="AU" term="%22De+Hert+SC%22">De Hert SC</searchLink>; School of Chemical and Bioprocess Engineering, University College Dublin, Dublin 4, Ireland.<br /><searchLink fieldCode="AU" term="%22Healy+AM%22">Healy AM</searchLink>; EPSRC-SFI Centre for Doctoral Training in Transformative Pharmaceutical Technologies, Ireland; SSPC, The Research Ireland Centre for Pharmaceuticals, School of Pharmacy and Pharmaceutical Sciences, Panoz Institute, Trinity College Dublin, Dublin 2, Ireland.<br /><searchLink fieldCode="AU" term="%22Ferguson+S%22">Ferguson S</searchLink>; School of Chemical and Bioprocess Engineering, University College Dublin, Dublin 4, Ireland; SSPC, The Research Ireland Centre for Pharmaceuticals, School of Chemical and Bioprocess Engineering, University College Dublin, Dublin 4, Ireland; EPSRC-SFI Centre for Doctoral Training in Transformative Pharmaceutical Technologies, Ireland; National Institute for Bioprocessing Research and Training, 24 Foster's Ave, Belfield, Blackrock, Co. Dublin A94 X099, Ireland. Electronic address: steven.ferguson@ucd.ie.
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