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Combining inter-eye differences enhances detection of optic nerve involvement in multiple sclerosis.

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Title: Combining inter-eye differences enhances detection of optic nerve involvement in multiple sclerosis.
Authors: Lin TY; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; Experimental and Clinical Research Center, Max Delbrück Center for Molecular Medicine and Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 13125 Berlin, Germany.; Neuroscience Clinical Research Center, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 10117 Berlin, Germany., McCormack B; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Bacchetti A; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Inserra M; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Filippatou A; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Pellegrini N; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Davis S; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Kim A; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Newsome SD; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Mowry EM; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Nourbakhsh B; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Bhargava P; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Pardo CA; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Kornberg MD; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Probasco JC; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Venkatesan A; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Dewey BE; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Balcer LJ; Department of Neurology, NYU Grossman School of Medicine, New York, NY 10017, USA.; Department of Population Health, NYU Grossman School of Medicine, New York, NY 10016, USA.; Department of Ophthalmology, NYU Grossman School of Medicine, New York, NY 10016, USA., Kenney RC; Department of Neurology, NYU Grossman School of Medicine, New York, NY 10017, USA.; Department of Population Health, NYU Grossman School of Medicine, New York, NY 10016, USA., Zimmermann HG; Experimental and Clinical Research Center, Max Delbrück Center for Molecular Medicine and Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 13125 Berlin, Germany.; Neuroscience Clinical Research Center, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 10117 Berlin, Germany.; Einstein Center Digital Future, 10117 Berlin, Germany., Oertel FC; Experimental and Clinical Research Center, Max Delbrück Center for Molecular Medicine and Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 13125 Berlin, Germany.; Neuroscience Clinical Research Center, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 10117 Berlin, Germany., Fitzgerald KC; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21287, USA., Sotirchos ES; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Paul F; Experimental and Clinical Research Center, Max Delbrück Center for Molecular Medicine and Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 13125 Berlin, Germany.; Neuroscience Clinical Research Center, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 10117 Berlin, Germany.; Einstein Center Digital Future, 10117 Berlin, Germany., Calabresi PA; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Saidha S; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
Source: Brain : a journal of neurology [Brain] 2025 Nov 26. Date of Electronic Publication: 2025 Nov 26.
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0372537 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2156 (Electronic) Linking ISSN: 00068950 NLM ISO Abbreviation: Brain Subsets: MEDLINE
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  Data: Combining inter-eye differences enhances detection of optic nerve involvement in multiple sclerosis.
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  Data: <searchLink fieldCode="AU" term="%22Lin+TY%22">Lin TY</searchLink>; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; Experimental and Clinical Research Center, Max Delbrück Center for Molecular Medicine and Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 13125 Berlin, Germany.; Neuroscience Clinical Research Center, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 10117 Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22McCormack+B%22">McCormack B</searchLink>; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.<br /><searchLink fieldCode="AU" term="%22Bacchetti+A%22">Bacchetti A</searchLink>; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.<br /><searchLink fieldCode="AU" term="%22Inserra+M%22">Inserra M</searchLink>; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.<br /><searchLink fieldCode="AU" term="%22Filippatou+A%22">Filippatou A</searchLink>; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.<br /><searchLink fieldCode="AU" term="%22Pellegrini+N%22">Pellegrini N</searchLink>; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.<br /><searchLink fieldCode="AU" term="%22Davis+S%22">Davis S</searchLink>; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.<br /><searchLink fieldCode="AU" term="%22Kim+A%22">Kim A</searchLink>; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.<br /><searchLink fieldCode="AU" term="%22Newsome+SD%22">Newsome SD</searchLink>; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.<br /><searchLink fieldCode="AU" term="%22Mowry+EM%22">Mowry EM</searchLink>; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.<br /><searchLink fieldCode="AU" term="%22Nourbakhsh+B%22">Nourbakhsh B</searchLink>; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.<br /><searchLink fieldCode="AU" term="%22Bhargava+P%22">Bhargava P</searchLink>; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.<br /><searchLink fieldCode="AU" term="%22Pardo+CA%22">Pardo CA</searchLink>; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.<br /><searchLink fieldCode="AU" term="%22Kornberg+MD%22">Kornberg MD</searchLink>; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.<br /><searchLink fieldCode="AU" term="%22Probasco+JC%22">Probasco JC</searchLink>; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.<br /><searchLink fieldCode="AU" term="%22Venkatesan+A%22">Venkatesan A</searchLink>; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.<br /><searchLink fieldCode="AU" term="%22Dewey+BE%22">Dewey BE</searchLink>; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.<br /><searchLink fieldCode="AU" term="%22Balcer+LJ%22">Balcer LJ</searchLink>; Department of Neurology, NYU Grossman School of Medicine, New York, NY 10017, USA.; Department of Population Health, NYU Grossman School of Medicine, New York, NY 10016, USA.; Department of Ophthalmology, NYU Grossman School of Medicine, New York, NY 10016, USA.<br /><searchLink fieldCode="AU" term="%22Kenney+RC%22">Kenney RC</searchLink>; Department of Neurology, NYU Grossman School of Medicine, New York, NY 10017, USA.; Department of Population Health, NYU Grossman School of Medicine, New York, NY 10016, USA.<br /><searchLink fieldCode="AU" term="%22Zimmermann+HG%22">Zimmermann HG</searchLink>; Experimental and Clinical Research Center, Max Delbrück Center for Molecular Medicine and Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 13125 Berlin, Germany.; Neuroscience Clinical Research Center, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 10117 Berlin, Germany.; Einstein Center Digital Future, 10117 Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Oertel+FC%22">Oertel FC</searchLink>; Experimental and Clinical Research Center, Max Delbrück Center for Molecular Medicine and Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 13125 Berlin, Germany.; Neuroscience Clinical Research Center, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 10117 Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Fitzgerald+KC%22">Fitzgerald KC</searchLink>; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21287, USA.<br /><searchLink fieldCode="AU" term="%22Sotirchos+ES%22">Sotirchos ES</searchLink>; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.<br /><searchLink fieldCode="AU" term="%22Paul+F%22">Paul F</searchLink>; Experimental and Clinical Research Center, Max Delbrück Center for Molecular Medicine and Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 13125 Berlin, Germany.; Neuroscience Clinical Research Center, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 10117 Berlin, Germany.; Einstein Center Digital Future, 10117 Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Calabresi+PA%22">Calabresi PA</searchLink>; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.<br /><searchLink fieldCode="AU" term="%22Saidha+S%22">Saidha S</searchLink>; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
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