View in EDS HTML Full Text PDF Full Text

Lymphotoxin alpha eradicates acute myeloid leukemia and simultaneously promotes healthy hematopoiesis in mice.

Saved in:
Bibliographic Details
Title: Lymphotoxin alpha eradicates acute myeloid leukemia and simultaneously promotes healthy hematopoiesis in mice.
Authors: Höckendorf U; Department of Internal Medicine III, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, München, Germany., Dutta S; Clinical Division of Oncology, Department of Internal Medicine, Medical University of Graz, Graz, Austria., Kloos A; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany., Runtsch M; Clinical Division of Oncology, Department of Internal Medicine, Medical University of Graz, Graz, Austria.; Cycuria Therapeutics, Graz, Austria., Zötsch C; Clinical Division of Oncology, Department of Internal Medicine, Medical University of Graz, Graz, Austria.; Cycuria Therapeutics, Graz, Austria., Vosberg S; Clinical Division of Oncology, Department of Internal Medicine, Medical University of Graz, Graz, Austria., Wang Y; Proteomics and Cancer Cell Signaling, DKFZ and Hopp Children's Cancer Center (KiTZ), Heidelberg, Germany and Department of Pediatric Oncology, Hematology, and Immunology, University of Heidelberg, Heidelberg, Germany., Kienreich S; Clinical Division of Oncology, Department of Internal Medicine, Medical University of Graz, Graz, Austria., Flasch B; Clinical Division of Oncology, Department of Internal Medicine, Medical University of Graz, Graz, Austria., Malovan G; Clinical Division of Oncology, Department of Internal Medicine, Medical University of Graz, Graz, Austria., Jäger V; Clinical Division of Oncology, Department of Internal Medicine, Medical University of Graz, Graz, Austria., Stanzer S; Clinical Division of Oncology, Department of Internal Medicine, Medical University of Graz, Graz, Austria., Prein S; Clinical Division of Oncology, Department of Internal Medicine, Medical University of Graz, Graz, Austria., Odinius TO; Department of Internal Medicine III, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, München, Germany.; Department of Medical Oncology and Hematology, University Hospital Zürich, Zürich, Switzerland., Wagner CV; Department of Internal Medicine III, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, München, Germany., Buschhorn L; Department of Internal Medicine III, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, München, Germany.; National Center for Tumor Diseases (NCT) Heidelberg, University Hospital and German Cancer Research Center (DKFZ), Heidelberg, Germany., Dill V; Department of Internal Medicine III, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, München, Germany., Perfler B; Division of Hematology, Department of Internal Medicine, Medical University of Graz, Graz, Austria.; Division of Pharmacology, Otto Loewi Research Center for Vascular Biology, Immunology, and Inflammation, Medical University of Graz, Graz, Austria., Haferlach T; Munich Leukemia Laboratory (MLL), Munich, Germany., Döhner K; Ulm University Hospital, Department of Internal Medicine III, Ulm, Germany., Götze KS; Department of Internal Medicine III, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, München, Germany.; German Cancer Consortium (DKTK), partner site Munich, a partnership between DKFZ and TUM University Hospital, Munich, Germany.; Bavarian Cancer Research Center (BZKF), Munich, Germany., Ruland J; German Cancer Consortium (DKTK), partner site Munich, a partnership between DKFZ and TUM University Hospital, Munich, Germany.; Institute of Clinical Chemistry and Pathobiochemistry, School of Medicine and Health, Technical University of Munich, Munich, Germany.; TranslaTUM, Center for Translational Cancer Research (TranslaTUM), Technical University of Munich, Munich, Germany., Bassermann F; Department of Internal Medicine III, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, München, Germany.; German Cancer Consortium (DKTK), partner site Munich, a partnership between DKFZ and TUM University Hospital, Munich, Germany.; Bavarian Cancer Research Center (BZKF), Munich, Germany.; TranslaTUM, Center for Translational Cancer Research (TranslaTUM), Technical University of Munich, Munich, Germany., Wahida A; Institute of Metabolism and Cell Death, Helmholtz Centre Munich, Neuherberg, Germany., Heikenwälder M; Division of Chronic Inflammation and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany., Branca C; Department of Internal Medicine III, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, München, Germany., Schmöllerl J; Research Institute of Molecular Pathology, Vienna BioCenter (VBC), Vienna, Austria., Zuber J; Research Institute of Molecular Pathology, Vienna BioCenter (VBC), Vienna, Austria.; Medical University of Vienna, Vienna BioCenter (VBC), Vienna, Austria., Burk AC; Faculty of Medicine, Clinic for Internal Medicine I, Hematology, Oncology and Stem Cell Transplantation, University Medical Center Freiburg, Freiburg, Germany., Zeiser R; Faculty of Medicine, Clinic for Internal Medicine I, Hematology, Oncology and Stem Cell Transplantation, University Medical Center Freiburg, Freiburg, Germany., Sill H; Division of Hematology, Department of Internal Medicine, Medical University of Graz, Graz, Austria., Jayavelu AK; Proteomics and Cancer Cell Signaling, DKFZ and Hopp Children's Cancer Center (KiTZ), Heidelberg, Germany and Department of Pediatric Oncology, Hematology, and Immunology, University of Heidelberg, Heidelberg, Germany., Zebisch A; Division of Hematology, Department of Internal Medicine, Medical University of Graz, Graz, Austria.; Division of Pharmacology, Otto Loewi Research Center for Vascular Biology, Immunology, and Inflammation, Medical University of Graz, Graz, Austria., Heuser M; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.; Department of Internal Medicine IV, University Hospital Halle (Saale), Martin-Luther-University Halle-Wittenberg, Halle, Germany., Dengler MA; Clinical Division of Oncology, Department of Internal Medicine, Medical University of Graz, Graz, Austria., Jost PJ; Department of Internal Medicine III, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, München, Germany.; Clinical Division of Oncology, Department of Internal Medicine, Medical University of Graz, Graz, Austria.; BioTechMed, Graz and Austrian Comprehensive Cancer Network (ACCN), Graz, Austria.
Source: Science translational medicine [Sci Transl Med] 2025 Nov 26; Vol. 17 (826), pp. eadu3313. Date of Electronic Publication: 2025 Nov 26.
Publication Type: Journal Article
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 41296826
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Lymphotoxin alpha eradicates acute myeloid leukemia and simultaneously promotes healthy hematopoiesis in mice.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Höckendorf+U%22">Höckendorf U</searchLink>; Department of Internal Medicine III, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, München, Germany.<br /><searchLink fieldCode="AU" term="%22Dutta+S%22">Dutta S</searchLink>; Clinical Division of Oncology, Department of Internal Medicine, Medical University of Graz, Graz, Austria.<br /><searchLink fieldCode="AU" term="%22Kloos+A%22">Kloos A</searchLink>; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Runtsch+M%22">Runtsch M</searchLink>; Clinical Division of Oncology, Department of Internal Medicine, Medical University of Graz, Graz, Austria.; Cycuria Therapeutics, Graz, Austria.<br /><searchLink fieldCode="AU" term="%22Zötsch+C%22">Zötsch C</searchLink>; Clinical Division of Oncology, Department of Internal Medicine, Medical University of Graz, Graz, Austria.; Cycuria Therapeutics, Graz, Austria.<br /><searchLink fieldCode="AU" term="%22Vosberg+S%22">Vosberg S</searchLink>; Clinical Division of Oncology, Department of Internal Medicine, Medical University of Graz, Graz, Austria.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Proteomics and Cancer Cell Signaling, DKFZ and Hopp Children's Cancer Center (KiTZ), Heidelberg, Germany and Department of Pediatric Oncology, Hematology, and Immunology, University of Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Kienreich+S%22">Kienreich S</searchLink>; Clinical Division of Oncology, Department of Internal Medicine, Medical University of Graz, Graz, Austria.<br /><searchLink fieldCode="AU" term="%22Flasch+B%22">Flasch B</searchLink>; Clinical Division of Oncology, Department of Internal Medicine, Medical University of Graz, Graz, Austria.<br /><searchLink fieldCode="AU" term="%22Malovan+G%22">Malovan G</searchLink>; Clinical Division of Oncology, Department of Internal Medicine, Medical University of Graz, Graz, Austria.<br /><searchLink fieldCode="AU" term="%22Jäger+V%22">Jäger V</searchLink>; Clinical Division of Oncology, Department of Internal Medicine, Medical University of Graz, Graz, Austria.<br /><searchLink fieldCode="AU" term="%22Stanzer+S%22">Stanzer S</searchLink>; Clinical Division of Oncology, Department of Internal Medicine, Medical University of Graz, Graz, Austria.<br /><searchLink fieldCode="AU" term="%22Prein+S%22">Prein S</searchLink>; Clinical Division of Oncology, Department of Internal Medicine, Medical University of Graz, Graz, Austria.<br /><searchLink fieldCode="AU" term="%22Odinius+TO%22">Odinius TO</searchLink>; Department of Internal Medicine III, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, München, Germany.; Department of Medical Oncology and Hematology, University Hospital Zürich, Zürich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Wagner+CV%22">Wagner CV</searchLink>; Department of Internal Medicine III, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, München, Germany.<br /><searchLink fieldCode="AU" term="%22Buschhorn+L%22">Buschhorn L</searchLink>; Department of Internal Medicine III, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, München, Germany.; National Center for Tumor Diseases (NCT) Heidelberg, University Hospital and German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Dill+V%22">Dill V</searchLink>; Department of Internal Medicine III, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, München, Germany.<br /><searchLink fieldCode="AU" term="%22Perfler+B%22">Perfler B</searchLink>; Division of Hematology, Department of Internal Medicine, Medical University of Graz, Graz, Austria.; Division of Pharmacology, Otto Loewi Research Center for Vascular Biology, Immunology, and Inflammation, Medical University of Graz, Graz, Austria.<br /><searchLink fieldCode="AU" term="%22Haferlach+T%22">Haferlach T</searchLink>; Munich Leukemia Laboratory (MLL), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Döhner+K%22">Döhner K</searchLink>; Ulm University Hospital, Department of Internal Medicine III, Ulm, Germany.<br /><searchLink fieldCode="AU" term="%22Götze+KS%22">Götze KS</searchLink>; Department of Internal Medicine III, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, München, Germany.; German Cancer Consortium (DKTK), partner site Munich, a partnership between DKFZ and TUM University Hospital, Munich, Germany.; Bavarian Cancer Research Center (BZKF), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Ruland+J%22">Ruland J</searchLink>; German Cancer Consortium (DKTK), partner site Munich, a partnership between DKFZ and TUM University Hospital, Munich, Germany.; Institute of Clinical Chemistry and Pathobiochemistry, School of Medicine and Health, Technical University of Munich, Munich, Germany.; TranslaTUM, Center for Translational Cancer Research (TranslaTUM), Technical University of Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Bassermann+F%22">Bassermann F</searchLink>; Department of Internal Medicine III, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, München, Germany.; German Cancer Consortium (DKTK), partner site Munich, a partnership between DKFZ and TUM University Hospital, Munich, Germany.; Bavarian Cancer Research Center (BZKF), Munich, Germany.; TranslaTUM, Center for Translational Cancer Research (TranslaTUM), Technical University of Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Wahida+A%22">Wahida A</searchLink>; Institute of Metabolism and Cell Death, Helmholtz Centre Munich, Neuherberg, Germany.<br /><searchLink fieldCode="AU" term="%22Heikenwälder+M%22">Heikenwälder M</searchLink>; Division of Chronic Inflammation and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Branca+C%22">Branca C</searchLink>; Department of Internal Medicine III, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, München, Germany.<br /><searchLink fieldCode="AU" term="%22Schmöllerl+J%22">Schmöllerl J</searchLink>; Research Institute of Molecular Pathology, Vienna BioCenter (VBC), Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Zuber+J%22">Zuber J</searchLink>; Research Institute of Molecular Pathology, Vienna BioCenter (VBC), Vienna, Austria.; Medical University of Vienna, Vienna BioCenter (VBC), Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Burk+AC%22">Burk AC</searchLink>; Faculty of Medicine, Clinic for Internal Medicine I, Hematology, Oncology and Stem Cell Transplantation, University Medical Center Freiburg, Freiburg, Germany.<br /><searchLink fieldCode="AU" term="%22Zeiser+R%22">Zeiser R</searchLink>; Faculty of Medicine, Clinic for Internal Medicine I, Hematology, Oncology and Stem Cell Transplantation, University Medical Center Freiburg, Freiburg, Germany.<br /><searchLink fieldCode="AU" term="%22Sill+H%22">Sill H</searchLink>; Division of Hematology, Department of Internal Medicine, Medical University of Graz, Graz, Austria.<br /><searchLink fieldCode="AU" term="%22Jayavelu+AK%22">Jayavelu AK</searchLink>; Proteomics and Cancer Cell Signaling, DKFZ and Hopp Children's Cancer Center (KiTZ), Heidelberg, Germany and Department of Pediatric Oncology, Hematology, and Immunology, University of Heidelberg, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Zebisch+A%22">Zebisch A</searchLink>; Division of Hematology, Department of Internal Medicine, Medical University of Graz, Graz, Austria.; Division of Pharmacology, Otto Loewi Research Center for Vascular Biology, Immunology, and Inflammation, Medical University of Graz, Graz, Austria.<br /><searchLink fieldCode="AU" term="%22Heuser+M%22">Heuser M</searchLink>; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.; Department of Internal Medicine IV, University Hospital Halle (Saale), Martin-Luther-University Halle-Wittenberg, Halle, Germany.<br /><searchLink fieldCode="AU" term="%22Dengler+MA%22">Dengler MA</searchLink>; Clinical Division of Oncology, Department of Internal Medicine, Medical University of Graz, Graz, Austria.<br /><searchLink fieldCode="AU" term="%22Jost+PJ%22">Jost PJ</searchLink>; Department of Internal Medicine III, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, München, Germany.; Clinical Division of Oncology, Department of Internal Medicine, Medical University of Graz, Graz, Austria.; BioTechMed, Graz and Austrian Comprehensive Cancer Network (ACCN), Graz, Austria.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101505086%22">Science translational medicine</searchLink> [Sci Transl Med] 2025 Nov 26; Vol. 17 (826), pp. eadu3313. <i>Date of Electronic Publication: </i>2025 Nov 26.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+the+Advancement+of+Science%22">American Association for the Advancement of Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101505086 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1946-6242 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219466234%22">19466234 </searchLink><i>NLM ISO Abbreviation: </i>Sci Transl Med <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41296826
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1126/scitranslmed.adu3313
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: eadu3313
    Titles:
      – TitleFull: Lymphotoxin alpha eradicates acute myeloid leukemia and simultaneously promotes healthy hematopoiesis in mice.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Höckendorf U
      – PersonEntity:
          Name:
            NameFull: Dutta S
      – PersonEntity:
          Name:
            NameFull: Kloos A
      – PersonEntity:
          Name:
            NameFull: Runtsch M
      – PersonEntity:
          Name:
            NameFull: Zötsch C
      – PersonEntity:
          Name:
            NameFull: Vosberg S
      – PersonEntity:
          Name:
            NameFull: Wang Y
      – PersonEntity:
          Name:
            NameFull: Kienreich S
      – PersonEntity:
          Name:
            NameFull: Flasch B
      – PersonEntity:
          Name:
            NameFull: Malovan G
      – PersonEntity:
          Name:
            NameFull: Jäger V
      – PersonEntity:
          Name:
            NameFull: Stanzer S
      – PersonEntity:
          Name:
            NameFull: Prein S
      – PersonEntity:
          Name:
            NameFull: Odinius TO
      – PersonEntity:
          Name:
            NameFull: Wagner CV
      – PersonEntity:
          Name:
            NameFull: Buschhorn L
      – PersonEntity:
          Name:
            NameFull: Dill V
      – PersonEntity:
          Name:
            NameFull: Perfler B
      – PersonEntity:
          Name:
            NameFull: Haferlach T
      – PersonEntity:
          Name:
            NameFull: Döhner K
      – PersonEntity:
          Name:
            NameFull: Götze KS
      – PersonEntity:
          Name:
            NameFull: Ruland J
      – PersonEntity:
          Name:
            NameFull: Bassermann F
      – PersonEntity:
          Name:
            NameFull: Wahida A
      – PersonEntity:
          Name:
            NameFull: Heikenwälder M
      – PersonEntity:
          Name:
            NameFull: Branca C
      – PersonEntity:
          Name:
            NameFull: Schmöllerl J
      – PersonEntity:
          Name:
            NameFull: Zuber J
      – PersonEntity:
          Name:
            NameFull: Burk AC
      – PersonEntity:
          Name:
            NameFull: Zeiser R
      – PersonEntity:
          Name:
            NameFull: Sill H
      – PersonEntity:
          Name:
            NameFull: Jayavelu AK
      – PersonEntity:
          Name:
            NameFull: Zebisch A
      – PersonEntity:
          Name:
            NameFull: Heuser M
      – PersonEntity:
          Name:
            NameFull: Dengler MA
      – PersonEntity:
          Name:
            NameFull: Jost PJ
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 26
              M: 11
              Text: 2025 Nov 26
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-electronic
              Value: 1946-6242
          Numbering:
            – Type: volume
              Value: 17
            – Type: issue
              Value: 826
          Titles:
            – TitleFull: Science translational medicine
              Type: main
ResultId 1