Structural details of helix-mediated multimerization of the conserved region of TDP-43 C-terminal domain.

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Title: Structural details of helix-mediated multimerization of the conserved region of TDP-43 C-terminal domain.
Authors: Rizuan A; Artie McFerrin Department of Chemical Engineering, Texas A&M University, College Station, TX, USA., Shenoy J; Department of Molecular Biology, Cell Biology & Biochemistry, Brown University, Providence, RI, USA., Mohanty P; Artie McFerrin Department of Chemical Engineering, Texas A&M University, College Station, TX, USA., Dos Passos PM; Edward Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis, MO, USA., Mercado Ortiz JF; Department of Molecular Biology, Cell Biology & Biochemistry, Brown University, Providence, RI, USA., Bai L; Department of Molecular Biology, Cell Biology & Biochemistry, Brown University, Providence, RI, USA., Viswanathan R; Department of Molecular Biology, Cell Biology & Biochemistry, Brown University, Providence, RI, USA., Zaborowksy J; Department of Molecular Biology, Cell Biology & Biochemistry, Brown University, Providence, RI, USA., Wang SH; Department of Molecular Biology, Cell Biology & Biochemistry, Brown University, Providence, RI, USA., Johnson V; Department of Molecular Biology, Cell Biology & Biochemistry, Brown University, Providence, RI, USA., Mamede LD; Edward Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis, MO, USA., Titus AR; Edward Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis, MO, USA., Ayala YM; Edward Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis, MO, USA., Ghirlando R; Laboratory of Molecular Biology, National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA., Mittal J; Artie McFerrin Department of Chemical Engineering, Texas A&M University, College Station, TX, USA. jeetain@tamu.edu.; Department of Chemistry, Texas A&M University, College Station, TX, USA. jeetain@tamu.edu.; Interdisciplinary Graduate Program in Genetics and Genomics, Texas A&M University, College Station, TX, USA. jeetain@tamu.edu., Fawzi NL; Department of Molecular Biology, Cell Biology & Biochemistry, Brown University, Providence, RI, USA. nicolas_fawzi@brown.edu.
Source: Nature communications [Nat Commun] 2025 Nov 26; Vol. 16 (1), pp. 10528. Date of Electronic Publication: 2025 Nov 26.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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