Torsion is a dynamic regulator of DNA replication stalling and reactivation.

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Title: Torsion is a dynamic regulator of DNA replication stalling and reactivation.
Authors: Jia X; Howard Hughes Medical Institute, Cornell University, Ithaca, NY, USA.; Department of Physics & LASSP, Cornell University, Ithaca, NY, USA., Gao X; Howard Hughes Medical Institute, Cornell University, Ithaca, NY, USA.; Department of Physics & LASSP, Cornell University, Ithaca, NY, USA., Zhang S; Howard Hughes Medical Institute, Cornell University, Ithaca, NY, USA.; Department of Physics & LASSP, Cornell University, Ithaca, NY, USA., Inman JT; Howard Hughes Medical Institute, Cornell University, Ithaca, NY, USA.; Department of Physics & LASSP, Cornell University, Ithaca, NY, USA., Hong Y; Department of Electrical and Computer Engineering, Cornell University, Ithaca, NY, USA., Singh A; Department of Biochemistry and Molecular Biology, Robert Wood Johnson Medical School, Rutgers University, Piscataway, NJ, USA., Rashid F; Department of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Berger JM; Department of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Patel SS; Department of Biochemistry and Molecular Biology, Robert Wood Johnson Medical School, Rutgers University, Piscataway, NJ, USA., Wang MD; Howard Hughes Medical Institute, Cornell University, Ithaca, NY, USA. mwang@physics.cornell.edu.; Department of Physics & LASSP, Cornell University, Ithaca, NY, USA. mwang@physics.cornell.edu.
Source: Nature communications [Nat Commun] 2025 Nov 26; Vol. 16 (1), pp. 10543. Date of Electronic Publication: 2025 Nov 26.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-025-65567-5