Differential protein expression and enriched pathways in pediatric sepsis: identification of novel brain-associated biomarkers revealed through proteomic profiling.

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Title: Differential protein expression and enriched pathways in pediatric sepsis: identification of novel brain-associated biomarkers revealed through proteomic profiling.
Authors: Stranges V; Maternal and Child Health and Urological Sciences, Policlinico Umberto I, Rome, Italy., Tweddell D; Computer Science, Western University, London, ON, Canada., Cela E; Physiology and Pharmacology, Western University, London, ON, Canada., Morello M; Experimental Medicine, University of Rome Tor Vergata, Rome, Italy., Daley M; Computer Science, Western University, London, ON, Canada.; Epidemiology and Biostatistics, Western University, London, ON, Canada., Cepinskas G; Medical Biophysics, Western University, London, ON, Canada.; Anatomy and Cell Biology, Western University, London, ON, Canada.; London Health Sciences Centre Research Institute, 800 Commissioners Road East, London, ON, Canada., Fraser DD; Physiology and Pharmacology, Western University, London, ON, Canada. douglas.fraser@lhsc.on.ca.; London Health Sciences Centre Research Institute, 800 Commissioners Road East, London, ON, Canada. douglas.fraser@lhsc.on.ca.; Pediatrics, Western University, London, ON, Canada. douglas.fraser@lhsc.on.ca.; Clinical Neurological Sciences, Western University, London, ON, Canada. douglas.fraser@lhsc.on.ca.; Children's Health Research Institute, London, ON, Canada. douglas.fraser@lhsc.on.ca.; GSK Chair in Clinical Pharmacology, Western University, London, ON, Canada. douglas.fraser@lhsc.on.ca.
Source: Molecular medicine (Cambridge, Mass.) [Mol Med] 2025 Nov 26; Vol. 32 (1), pp. 14. Date of Electronic Publication: 2025 Nov 26.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 9501023 Publication Model: Electronic Cited Medium: Internet ISSN: 1528-3658 (Electronic) Linking ISSN: 10761551 NLM ISO Abbreviation: Mol Med Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1528-3658
DOI:10.1186/s10020-025-01397-x