Isotopic H/D Exchange in Hydrogen Bonds Between the Nitrogenous Bases of the CAG Repeat Tract Makes It Possible to Stabilize Its Expansion in the ATXN2 Gene.

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Title: Isotopic H/D Exchange in Hydrogen Bonds Between the Nitrogenous Bases of the CAG Repeat Tract Makes It Possible to Stabilize Its Expansion in the ATXN2 Gene.
Authors: Dorohova A; Scientific Department, Kuban State University, 350040 Krasnodar, Russia.; Laboratory of Problems of Stable Isotope Spreading in Living Systems, Southern Scientific Center of the Russian Academy of Sciences, 344006 Rostov-on-Don, Russia., Velázquez-Pérez L; President's Office, Cuban Academy of Sciences, La Habana 10100, Cuba., Drobotenko M; Scientific Department, Kuban State University, 350040 Krasnodar, Russia.; Laboratory of Problems of Stable Isotope Spreading in Living Systems, Southern Scientific Center of the Russian Academy of Sciences, 344006 Rostov-on-Don, Russia., Lyasota O; Scientific Department, Kuban State University, 350040 Krasnodar, Russia.; Laboratory of Problems of Stable Isotope Spreading in Living Systems, Southern Scientific Center of the Russian Academy of Sciences, 344006 Rostov-on-Don, Russia., Hernandez-Caceres JL; Neurodevelopment Branch, Cuban Center for Neurosciences, La Habana 11600, Cuba.; Joint Institute of Nuclear Research, 141980 Dubna, Russia., Rodriguez-Labrada R; Neurodevelopment Branch, Cuban Center for Neurosciences, La Habana 11600, Cuba., Svidlov A; Scientific Department, Kuban State University, 350040 Krasnodar, Russia., Leontyeva O; Scientific Department, Kuban State University, 350040 Krasnodar, Russia.; Laboratory of Problems of Stable Isotope Spreading in Living Systems, Southern Scientific Center of the Russian Academy of Sciences, 344006 Rostov-on-Don, Russia., Nechipurenko Y; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia., Dzhimak S; Scientific Department, Kuban State University, 350040 Krasnodar, Russia.; Laboratory of Problems of Stable Isotope Spreading in Living Systems, Southern Scientific Center of the Russian Academy of Sciences, 344006 Rostov-on-Don, Russia.
Source: Biomedicines [Biomedicines] 2025 Nov 04; Vol. 13 (11). Date of Electronic Publication: 2025 Nov 04.
Publication Type: Journal Article
Journal Info: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101691304 Publication Model: Electronic Cited Medium: Print ISSN: 2227-9059 (Print) Linking ISSN: 22279059 NLM ISO Abbreviation: Biomedicines Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:2227-9059
DOI:10.3390/biomedicines13112708