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Disproportionate impairment in diffusing capacity predicts pulmonary hypertension with an elevated pulmonary vascular resistance in COPD.

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Title: Disproportionate impairment in diffusing capacity predicts pulmonary hypertension with an elevated pulmonary vascular resistance in COPD.
Authors: Balasubramanian A; Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, Maryland, USA., Hemnes AR; Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Brittain EL; Division of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Annis J; Division of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Fawzy A; Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, Maryland, USA., Putcha N; Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, Maryland, USA., Singh A; Division of Pulmonary and Critical Care Medicine, Alleghany Health Network, Pittsburgh, Pennsylvania, USA., Wise RA; Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, Maryland, USA., Hansel NN; Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, Maryland, USA., Simpson C; Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, Maryland, USA., Kolb TM; Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, Maryland, USA., Hassoun PM; Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, Maryland, USA., McCormack MC; Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, Maryland, USA., Mathai SC; Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, Maryland, USA smathai4@jhmi.edu.
Source: Thorax [Thorax] 2026 May 14; Vol. 81 (6), pp. 524-532. Date of Electronic Publication: 2026 May 14.
Publication Type: Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: British Medical Assn Country of Publication: England NLM ID: 0417353 Publication Model: Electronic Cited Medium: Internet ISSN: 1468-3296 (Electronic) Linking ISSN: 00406376 NLM ISO Abbreviation: Thorax Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Balasubramanian+A%22">Balasubramanian A</searchLink>; Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Hemnes+AR%22">Hemnes AR</searchLink>; Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.<br /><searchLink fieldCode="AU" term="%22Brittain+EL%22">Brittain EL</searchLink>; Division of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.<br /><searchLink fieldCode="AU" term="%22Annis+J%22">Annis J</searchLink>; Division of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.<br /><searchLink fieldCode="AU" term="%22Fawzy+A%22">Fawzy A</searchLink>; Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Putcha+N%22">Putcha N</searchLink>; Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Singh+A%22">Singh A</searchLink>; Division of Pulmonary and Critical Care Medicine, Alleghany Health Network, Pittsburgh, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Wise+RA%22">Wise RA</searchLink>; Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Hansel+NN%22">Hansel NN</searchLink>; Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Simpson+C%22">Simpson C</searchLink>; Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Kolb+TM%22">Kolb TM</searchLink>; Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Hassoun+PM%22">Hassoun PM</searchLink>; Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22McCormack+MC%22">McCormack MC</searchLink>; Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Mathai+SC%22">Mathai SC</searchLink>; Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, Maryland, USA smathai4@jhmi.edu.
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  Data: <searchLink fieldCode="JN" term="%220417353%22">Thorax</searchLink> [Thorax] 2026 May 14; Vol. 81 (6), pp. 524-532. <i>Date of Electronic Publication: </i>2026 May 14.
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              Text: 2026 May 14
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